Protein Alignment myo and Inhba

DIOPT Version :10

• Sequence 1: NP_726604.1
• Gene: myo / 43811
• FlyBaseID: FBgn0026199
• Length: 598
• Species: Drosophila melanogaster
• Sequence 2: NP_058824.1
• Gene: Inhba / 29200
• RGDID: 62074
• Length: 424
• Species: Rattus norvegicus
• Alignment Length: 445
• Identity: 94/445 - (21%)
• Similarity: 168/445 - (37%)
• Gaps: 124/445 - (27%)

  Fly   205 DSIESIKMHILMRLNLKKLPNITKPISVPQNIIDNFYRDYNASSKTTVWNRMESIDESHLSINDT 269
            :.:|::|.|||..|:|||.|::|:|  ||:..:.|..|..:.....         :..::.|.|.
  Rat    53 EMVEAVKKHILNMLHLKKRPDVTQP--VPKAALLNAIRKLHVGKVG---------ENGYVEIEDD 106

  Fly   270 YGDHIMTDFFDESSSSQMQGDDANTVNEFL-IDLNKNQAKKSDIPINTNDEEYESILSHISSIYI 333
            .|.....:...|.:|..:...::.|..:.| .:::|   :.||:.:....|           :::
  Rat   107 IGRRAEMNELMEQTSEIITFAESGTARKTLHFEISK---EGSDLSVVERAE-----------VWL 157

  Fly   334 FPEEIQPHVRHNR-KVDVFRFQIDSSYSDLSYATLHLYLRGWDWISAHQPGLL------EEIKKQ 391
            |.:  .|.....| ||.:..||...                      |..|.|      ||:..:
  Rat   158 FLK--VPKANRTRTKVTIRLFQQQK----------------------HPQGSLDMGDEAEEMGLK 198

  Fly   392 PRKDIVVTIHRAIRVANTTSFNPKVKMFEFRHSIPSGLGQWVAVDLKSLLGNLGSNMTQEILIKG 456
            ..:..::...:.:....:|           .|..|      |:..::.||....|::...|..:.
  Rat   199 GERSELLLSEKVVDARKST-----------WHIFP------VSSSIQRLLDQGKSSLDVRIACEQ 246

  Fly   457 AETWMKSLV---------VTTDNTSKNPLTVHIEIGSQKKHR---------------RKRSVYMD 497
            .:....|||         |..|...|:.....:|...::.||               |:|...::
  Rat   247 CQESGASLVLLGKKKKKEVDGDGKKKDGSDGGLEEEKEQSHRPFLMLQARQSEDHPHRRRRRGLE 311

  Fly   498 CTENDHDMR-CCRYPLKVNFTSFGWH-FVVAPTSFDAYFCSGDCK-----------------VGY 543
            |   |..:. ||:....|:|...||: :::||:.:.|.:|.|:|.                 :.:
  Rat   312 C---DGKVNICCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINH 373

  Fly   544 LEQYPHTHLAALTTSATPCCSPTKMSSLSLLYFDDNHNLVLSVIPNMSVEGCSCS 598
            .....|:..|.|.:    ||.|||:..:|:||:||..|::...|.||.||.|.||
  Rat   374 YRMRGHSPFANLKS----CCVPTKLRPMSMLYYDDGQNIIKKDIQNMIVEECGCS 424

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
myo	NP_726604.1	TGF_beta_GDF8_like	506..597	CDD:381629	32/109 (29%)
Inhba	NP_058824.1	TGFb_propeptide	56..291	CDD:480997	56/300 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	264..306		7/41 (17%)
		TGF_beta_INHBA	317..424	CDD:381674	32/110 (29%)