DRSC/TRiP Functional Genomics Resources

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Protein Alignment myo and Gdf2

DIOPT Version :9

Sequence 1:NP_726604.1 Gene:myo / 43811 FlyBaseID:FBgn0026199 Length:598 Species:Drosophila melanogaster
Sequence 2:NP_001099566.1 Gene:Gdf2 / 290921 RGDID:1586196 Length:430 Species:Rattus norvegicus


Alignment Length:462 Identity:107/462 - (23%)
Similarity:168/462 - (36%) Gaps:142/462 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   199 REKAKVD---SIESIKMHILMRLNLKKLPNITKP-ISVPQNIIDNFYRDYNASSKTTVWNRMESI 259
            ||:...|   .:|::|:..|..|||..:|:..|. ...||.:||.:.|.....|.|...|.:.| 
  Rat    47 REEGVFDLKMFLENMKVDFLRSLNLSGIPSQDKTRAEPPQYMIDLYNRYTTDKSSTPASNIVRS- 110

  Fly   260 DESHLSINDTYGDHIMTDF-FDESSSSQMQGDDANTVNEFLIDLNKN-QAKKSDIPINTNDEEYE 322
                .|:.|........|| |.:.            :..|.|.:.:: |..::::.:      |.
  Rat   111 ----FSVEDAISTAATEDFPFQKH------------ILIFNISIPRHEQITRAELRL------YV 153

  Fly   323 SILSHISSIYIFPEEIQPHVRHNRKVDVFRFQIDSSYSDLSYATLHLYLR-----GWDWISAHQP 382
            |..:|:.|         .|......|......:|.::...|.....|..:     ||:.:     
  Rat   154 SCQNHVDS---------THGLEGNMVVYDVLDVDETWDSASGTKTFLVSQDIQDEGWETL----- 204

  Fly   383 GLLEEIKKQPRKDIVVTIHRAIRVANTTSFNPKVKMFEFRH---------SIPSG---LGQWVA- 434
                        ::...:.|.:|..:||:.| |:::...||         |:|.|   |..:|. 
  Rat   205 ------------EVSSAVKRWVRADSTTNKN-KLEVTVQRHREGCSTLDISVPPGSQNLPFFVVF 256

  Fly   435 ------------VDLKSLLGNLGSNMTQE-ILIKGAETWMKSLVVTTDNTSKNPLTVHIEIGSQK 486
                        ::||.::|:     .|| :|:|               ||||   .:.|.|..:
  Rat   257 SNDRSNGTKETRLELKEMIGH-----EQETVLVK---------------TSKN---AYQEAGESR 298

  Fly   487 KH---------------RRKRSVYMDCTENDHDMRCCRYPLKVNFTSFGW-HFVVAPTSFDAYFC 535
            :.               |||||.   ...:.|   |.:..|:|||...|| .:::||..:|||.|
  Rat   299 EEEERIDGYTAVGPLLARRKRST---GAASSH---CQKTSLRVNFEDIGWDSWIIAPKEYDAYEC 357

  Fly   536 SGDCKVGYLEQYPHT---------HLAALTTSATPCCSPTKMSSLSLLYFDDNHNLVLSV-IPNM 590
            .|.|.....:....|         ||...|.....||.|||:|.:|:||.||.....|.. ...|
  Rat   358 KGGCFFPLADDVTPTKHAIVQTLVHLKFPTKVGKACCVPTKLSPISILYKDDMGVPTLKYHYEGM 422

  Fly   591 SVEGCSC 597
            ||..|.|
  Rat   423 SVAECGC 429

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
myoNP_726604.1 TGF_beta 506..597 CDD:278448 35/101 (35%)
Gdf2NP_001099566.1 TGFb_propeptide 75..256 CDD:279078 43/230 (19%)
TGF_beta 327..429 CDD:278448 36/104 (35%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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