Protein Alignment myo and GDF10

DIOPT Version :10

• Sequence 1: NP_726604.1
• Gene: myo / 43811
• FlyBaseID: FBgn0026199
• Length: 598
• Species: Drosophila melanogaster
• Sequence 2: NP_004953.1
• Gene: GDF10 / 2662
• HGNCID: 4215
• Length: 478
• Species: Homo sapiens
• Alignment Length: 314
• Identity: 80/314 - (25%)
• Similarity: 126/314 - (40%)
• Gaps: 92/314 - (29%)

  Fly   336 EEIQPHVRHNRKVD--VFRFQIDSSYSD-------------LSYA---------TLHLYLRGWDW 376
            ::|.|.|:..|:..  :...|:||...|             |.||         ::.:.|:.:|.
Human   204 KDISPIVKAARRDGELLLSAQLDSEERDPGVPRPSPYAPYILVYANDLAISEPNSVAVTLQRYDP 268

  Fly   377 ISAHQPGLLEEIKKQPRKDIVVTIHRAIRVANTTSFN---------PKVKMFEF-RHSIPSGLGQ 431
            ..|..|    |.:..|.......:.||.:.......|         |:.....| :|.:
Human   269 FPAGDP----EPRAAPNNSADPRVRRAAQATGPLQDNELPGLDERPPRAHAQHFHKHQL------ 323

  Fly   432 WVAVDLKSLLGNLGSNMTQEILIKGAETWM-KSLVVTTDNTSKNPLTVHIEIGSQKKHRRKRSVY 495
            |.: ..::|....|....::   ||.|.:| .|.|:..|..            :.:|.|||
Human   324 WPS-PFRALKPRPGRKDRRK---KGQEVFMAASQVLDFDEK------------TMQKARRK---- 368

  Fly   496 MDCTENDHDMRCCRYPLKVNFTSFGWH-FVVAPTSFDAYFCSGDCKVGYLEQYPHTHLAALTTSA 559
                :.|....|.|..|||:|...||: ::::|.|||||:|:|.|      ::|...:...:..|
Human   369 ----QWDEPRVCSRRYLKVDFADIGWNEWIISPKSFDAYYCAGAC------EFPMPKIVRPSNHA 423

  Fly   560 T----------------PCCSPTKMSSLSLLYFDDNHNLVLSVIPNMSVEGCSC 597
            |                |||.|.||:||.:|:.|:|.|:||.|.|||||:.|:|
Human   424 TIQSIVRAVGIIPGIPEPCCVPDKMNSLGVLFLDENRNVVLKVYPNMSVDTCAC 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
myo	NP_726604.1	TGF_beta_GDF8_like	506..597	CDD:381629	41/107 (38%)
GDF10	NP_004953.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	266..319		9/56 (16%)
		TGF_beta_GDF10	367..478	CDD:381664	45/125 (36%)