Protein Alignment myo and Tgfb3

DIOPT Version :10

• Sequence 1: NP_726604.1
• Gene: myo / 43811
• FlyBaseID: FBgn0026199
• Length: 598
• Species: Drosophila melanogaster
• Sequence 2: NP_037306.1
• Gene: Tgfb3 / 25717
• RGDID: 3851
• Length: 412
• Species: Rattus norvegicus
• Alignment Length: 511
• Identity: 101/511 - (19%)
• Similarity: 168/511 - (32%)
• Gaps: 198/511 - (38%)

  Fly   174 LSRVQSVSLYRNTLINIESMLQRQLREKAKVDSIESIKMHILMRLNLKKLPNITKPISVPQNIID 238
            |..:.:|||..:|...::.   ..:::|    .:|:|:..||.:|.|...|..:....||..::
  Rat    14 LLNLATVSLSLSTCTTLDF---GHIKKK----RVEAIRGQILSKLRLTSPPEPSVMTHVPYQVL- 70

  Fly   239 NFYRDYNASSKTTVWNRMESIDESHLSINDTYGDHIMTDFFDESSSSQMQGDDANTVNEFLIDLN 303
               ..||::        .|.::|.|       |:.       |...:|
  Rat    71 ---ALYNST--------RELLEEMH-------GER-------EEGCTQ----------------- 93

  Fly   304 KNQAKKSDIPINTNDEEYESILSHISSIYIFPEEIQPHVRHNRKV--------DVFRFQIDSSYS 360
                       .|::.||     :...|:.| :.||....||...        .||||.:.|
  Rat    94 -----------ETSESEY-----YAKEIHKF-DMIQGLAEHNELAVCPKGITSKVFRFNVSS--- 138

  Fly   361 DLSYATLHLYLRGWDWISAHQPGLLEEIKKQPRKDIVVTIHRAIRVANTTS--FNPKVKMFEF-- 421
                    :...|.:...|.                    .|.:||.|.:|  ...::::|:.
  Rat   139 --------VEKNGTNLFRAE--------------------FRVLRVPNPSSKRTEQRIELFQILR 175

  Fly   422 --RH----------SIPS-GLGQWVAVDLKSLL--------GNLGSNMT---------------- 449
              .|          ::|: |..:|::.|:...:        .|||..::
  Rat   176 PDEHIAKQRYIGGKNLPTRGTAEWLSFDVTDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILE 240

  Fly   450 -----QEILIKGAETWMKSLVVTTDNTSKNPLTVHIEIGSQKKH--------------------- 488
                 .||..||.:        ..|:..:..|.   .:..||.|
  Rat   241 NVHEVMEIKFKGVD--------NEDDHGRGDLG---RLKKQKDHHNPHLILMMIPPHRLDSPGQG 294

  Fly   489 --RRKRSVYMDCTENDHDMRCCRYPLKVNF-TSFGWHFVVAPTSFDAYFCSGDCKVGYLEQYPHT 550
              |:||::..:....:.:..||..||.::| ...||.:|..|..:.|.||||.|.  ||.....|
  Rat   295 GQRKKRALDTNYCFRNLEENCCVRPLYIDFRQDLGWKWVHEPKGYYANFCSGPCP--YLRSSDTT 357

  Fly   551 HLAAL--------TTSATPCCSPTKMSSLSLLYFDDNHNLVLSVIPNMSVEGCSCS 598
            |...|        ..||:|||.|..:..|::||:......| ..:.||.|:.|.||
  Rat   358 HSTVLGLYNTLNPEASASPCCVPQDLEPLTILYYVGRTPKV-EQLSNMVVKSCKCS 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
myo	NP_726604.1	TGF_beta_GDF8_like	506..597	CDD:381629	34/99 (34%)
Tgfb3	NP_037306.1	TGFb_propeptide	24..231	CDD:459906	49/304 (16%)
		Cell attachment site. /evidence=ECO:0000250|UniProtKB:P01137	261..263		0/1 (0%)
		TGF_beta_TGFB3	312..412	CDD:381656	34/102 (33%)