DRSC/TRiP Functional Genomics Resources

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Protein Alignment myo and Gdf7

DIOPT Version :9

Sequence 1:NP_726604.1 Gene:myo / 43811 FlyBaseID:FBgn0026199 Length:598 Species:Drosophila melanogaster
Sequence 2:XP_006239940.1 Gene:Gdf7 / 252833 RGDID:620105 Length:456 Species:Rattus norvegicus


Alignment Length:430 Identity:88/430 - (20%)
Similarity:152/430 - (35%) Gaps:121/430 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   232 VPQNIIDNFYRDYNA---SSKTTVWNRMESIDESHLSINDTYGDHIMTDFFDESSSSQMQGDDAN 293
            ||.:.:.:.||....   ::.|:...|:::|                |.|.|:::..:...:...
  Rat    83 VPHHFMMSLYRSLAGRAPAAATSGHGRVDTI----------------TGFTDQATQEESAAEPGQ 131

  Fly   294 TVNEFLIDLNKNQAKKSDIPINT----------NDEEYESILSHISSIYIFPEEI-QPHVRHNRK 347
            :   ||.|:  :....||..:|.          ..:...:.|..:..:...|:|. ..|:.|:|.
  Rat   132 S---FLFDV--SSLSDSDEVVNAELRVLRRRSPEPDRDSATLPPLLLLSTCPDEAGTAHLLHSRA 191

  Fly   348 VDVFRFQIDSSYSDLSYATLHLYLRGWDWISAHQPGLLEEIKKQPRKDIVVTIHRAIRVANTTSF 412
            .:    .:||:..:....|        |.:.:|:     ...:..||..:|.  ||:..|.::..
  Rat   192 AE----PLDSARWEAFDVT--------DAVQSHR-----RWPRTSRKFCLVL--RAVTGAESSPL 237

  Fly   413 NPKVKMFEFRHSIPSGLGQWVAVDLKSLLGNLGSNMTQE--ILIKGAETWMKSLVVTTDNTSKNP 475
            ..:...|.:    |.|             |:.|....:|  :|:..:.|..|..:..........
  Rat   238 ALRRLGFGW----PGG-------------GDGGGTAAEERALLVISSRTHRKESLFREIRAQARA 285

  Fly   476 LTVHIEI--------GSQKK---HRRKRSVYMDCTENDHD------------------------- 504
            |....|:        ||:|.   .||:|...:..|.....                         
  Rat   286 LRAAAELPPDPGLGAGSRKATPGGRRRRRTALAGTRGAQGSGGGGGGGGGGGGGGGGAGRGHGRR 350

  Fly   505 --MRCCRYPLKVNFTSFGW-HFVVAPTSFDAYFCSGDCKV---GYLEQYPHTHLAALTTSATP-- 561
              .||.|.||.|:|...|| .:::||..::||.|.|.|..   .:||...|..:..|..|..|  
  Rat   351 GRSRCSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGVCDFPLRSHLEPTNHAIIQTLLNSMAPDA 415

  Fly   562 ----CCSPTKMSSLSLLYFDDNHNLVLSVIPNMSVEGCSC 597
                ||.|.::|.:|:||.|..:|:|.....:|.||.|.|
  Rat   416 APASCCVPARLSPISILYIDAANNVVYKQYEDMVVEACGC 455

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
myoNP_726604.1 TGF_beta 506..597 CDD:278448 36/100 (36%)
Gdf7XP_006239940.1 TGFb_propeptide <87..230 CDD:279078 30/182 (16%)
TGF_beta 358..455 CDD:278448 33/96 (34%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
21.910

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