DRSC/TRiP Functional Genomics Resources

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Protein Alignment myo and Tgfb3

DIOPT Version :9

Sequence 1:NP_726604.1 Gene:myo / 43811 FlyBaseID:FBgn0026199 Length:598 Species:Drosophila melanogaster
Sequence 2:NP_033394.2 Gene:Tgfb3 / 21809 MGIID:98727 Length:412 Species:Mus musculus


Alignment Length:476 Identity:101/476 - (21%)
Similarity:158/476 - (33%) Gaps:179/476 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly   203 KVDSIESIKMHILMRLNLKKLPNITKPISVPQNIIDNFYRDYNASSKTTVWNRMESIDESHLSIN 267
            |...:|:|:..||.:|.|...|..:....||..::    ..||::        .|.::|.|    
Mouse    36 KKKRVEAIRGQILSKLRLTSPPEPSVMTHVPYQVL----ALYNST--------RELLEEMH---- 84

  Fly   268 DTYGDHIMTDFFDESSSSQMQGDDANTVNEFLIDLNKNQAKKSDIPINTNDEEYESILSHISSIY 332
               |:.       |...:|                            .|::.||     :...|:
Mouse    85 ---GER-------EEGCTQ----------------------------ETSESEY-----YAKEIH 106

  Fly   333 IFPEEIQPHVRHNRKV--------DVFRFQIDSSYSDLSYATLHLYLRGWDWISAHQPGLLEEIK 389
            .| :.||....||...        .||||.:.|           :...|.:...|.         
Mouse   107 KF-DMIQGLAEHNELAVCPKGITSKVFRFNVSS-----------VEKNGTNLFRAE--------- 150

  Fly   390 KQPRKDIVVTIHRAIRVANTTS--FNPKVKMFEF----RH----------SIPS-GLGQWVAVDL 437
                       .|.:||.|.:|  ...::::|:.    .|          ::|: |..:|::.|:
Mouse   151 -----------FRVLRVPNPSSKRTEQRIELFQILRPDEHIAKQRYIGGKNLPTRGTAEWLSFDV 204

  Fly   438 KSLL--------GNLGSNMT---------------------QEILIKGAETW-------MKSLVV 466
            ...:        .|||..::                     .||..||.:..       :..|..
Mouse   205 TDTVREWLLRRESNLGLEISIHCPCHTFQPNGDILENVHEVMEIKFKGVDNEDDHGRGDLGRLKK 269

  Fly   467 TTDNTSKNPLTVHIEI----------GSQKKHRRKRSVYMDCTENDHDMRCCRYPLKVNF-TSFG 520
            ..|:  .||..:.:.|          |||:|.|...:.|  |..|..: .||..||.::| ...|
Mouse   270 QKDH--HNPHLILMMIPPHRLDSPGQGSQRKKRALDTNY--CFRNLEE-NCCVRPLYIDFRQDLG 329

  Fly   521 WHFVVAPTSFDAYFCSGDCKVGYLEQYPHTHLAAL--------TTSATPCCSPTKMSSLSLLYFD 577
            |.:|..|..:.|.||||.|.  ||.....||...|        ..||:|||.|..:..|::||:.
Mouse   330 WKWVHEPKGYYANFCSGPCP--YLRSADTTHSTVLGLYNTLNPEASASPCCVPQDLEPLTILYYV 392

  Fly   578 DNHNLVLSVIPNMSVEGCSCS 598
            .....| ..:.||.|:.|.||
Mouse   393 GRTPKV-EQLSNMVVKSCKCS 412

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
myoNP_726604.1 TGF_beta 506..597 CDD:278448 34/99 (34%)
Tgfb3NP_033394.2 TGFb_propeptide 24..230 CDD:366248 48/284 (17%)
TGF_beta_TGFB3 312..412 CDD:381656 34/103 (33%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11848
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.010

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