Protein Alignment myo and Tgfb1

DIOPT Version :9

• Sequence 1: NP_726604.1
• Gene: myo / 43811
• FlyBaseID: FBgn0026199
• Length: 598
• Species: Drosophila melanogaster
• Sequence 2: NP_035707.1
• Gene: Tgfb1 / 21803
• MGIID: 98725
• Length: 390
• Species: Mus musculus
• Alignment Length: 449
• Identity: 89/449 - (19%)
• Similarity: 149/449 - (33%)
• Gaps: 147/449 - (32%)

  Fly   200 EKAKVDSIESIKMHILMRLNLKKLPN--ITKPISVPQNIID--NFYRDYNASSKTTVWNRMESID 260
            |..|...||:|:..||.:|.|...|:  ...|..:|:.::.  |..||..|.         ||.|
Mouse    39 ELVKRKRIEAIRGQILSKLRLASPPSQGEVPPGPLPEAVLALYNSTRDRVAG---------ESAD 94

  Fly   261 ESHLSINDTYGDHIMTDFFDESSSSQMQGDDANTVNEFLIDLNKNQAKKSDIPINTNDEEYESI- 324
            .......|.|                     |..|...|:             ::.|:..||..
Mouse    95 PEPEPEADYY---------------------AKEVTRVLM-------------VDRNNAIYEKTK 125

  Fly   325 -LSHISSIYIFPEEIQPHVRHNRKVDVFRFQIDSSYSDLSYATLHLYLRGWDWISAHQPGLLE-- 386
             :||  |||:|                      .:.||:..|             ..:|.||.
Mouse   126 DISH--SIYMF----------------------FNTSDIREA-------------VPEPPLLSRA 153

  Fly   387 EIKKQPRKDIVVTIHRAIRVANTTSFNPKVKMFEFRHSIPSGLGQWVAVDLKSLLG---NLGSNM 448
            |::.|..|.   ::.:.:.:....| |...:....|...|:...:|::.|:..::.   |.|.
Mouse   154 ELRLQRLKS---SVEQHVELYQKYS-NNSWRYLGNRLLTPTDTPEWLSFDVTGVVRQWLNQGD-- 212

  Fly   449 TQEILIKGAETWMKSLVVTTDNTSKNPLTVHIEIG------------------------------ 483
                   |.:.:..|...:.|:....   :|:||.
Mouse   213 -------GIQGFRFSAHCSCDSKDNK---LHVEINGISPKRRGDLGTIHDMNRPFLLLMATPLER 267

  Fly   484 SQKKH--RRKRSVYMDCTENDHDMRCCRYPLKVNF-TSFGWHFVVAPTSFDAYFCSGDCKVGYLE 545
            :|..|  |.:|::..:...:..:..||...|.::| ...||.::..|..:.|.||.|.|...:..
Mouse   268 AQHLHSSRHRRALDTNYCFSSTEKNCCVRQLYIDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSL 332

  Fly   546 QYPHTHLAAL------TTSATPCCSPTKMSSLSLLYFDDNHNLVLSVIPNMSVEGCSCS 598
            ...::.:.||      ..||:|||.|..:..|.::|:......| ..:.||.|..|.||
Mouse   333 DTQYSKVLALYNQHNPGASASPCCVPQALEPLPIVYYVGRKPKV-EQLSNMIVRSCKCS 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
myo	NP_726604.1	TGF_beta	506..597	CDD:278448	27/97 (28%)
Tgfb1	NP_035707.1	TGFb_propeptide	30..261	CDD:366248	56/317 (18%)
		Straightjacket domain. /evidence=ECO:0000250|UniProtKB:P07200	30..74		11/34 (32%)
		Arm domain. /evidence=ECO:0000250|UniProtKB:P07200	75..271		45/291 (15%)
		Bowtie tail. /evidence=ECO:0000250|UniProtKB:P01137	226..252		4/28 (14%)
		Cell attachment site. /evidence=ECO:0000255	244..246		0/1 (0%)
		TGF_beta_TGFB1	292..390	CDD:381654	27/98 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010