Protein Alignment myo and Gdf11

DIOPT Version :9

• Sequence 1: NP_726604.1
• Gene: myo / 43811
• FlyBaseID: FBgn0026199
• Length: 598
• Species: Drosophila melanogaster
• Sequence 2: NP_034402.1
• Gene: Gdf11 / 14561
• MGIID: 1338027
• Length: 405
• Species: Mus musculus
• Alignment Length: 439
• Identity: 113/439 - (25%)
• Similarity: 184/439 - (41%)
• Gaps: 139/439 - (31%)

  Fly   196 RQLREKAKVDSIESIKMHILMRLNLKKLPNITK-------PISVP-QNIIDNFYRDYNASSKTTV 252
            |:||       :||||..||.:|.||:.|||::       |.:.| |.|:|
Mouse    70 RELR-------LESIKSQILSKLRLKEAPNISREVVKQLLPKAPPLQQILD-------------- 113

  Fly   253 WNRMESIDESHLSINDTYGDHIM-TDFFDESSSSQMQGDDANTVNEFLIDLNKNQAKKSDIPINT 316
                         ::|..||.:. .||.:|        |:.:...|.:|.:    |:::|..:.|
Mouse   114 -------------LHDFQGDALQPEDFLEE--------DEYHATTETVISM----AQETDPAVQT 153

  Fly   317 NDEEYESILSHISSIYIFPEEIQPHVRHNRKVDVFRFQIDSSYSDLSYATLHLYLRGWDWISAHQ 381
            :.                    .|...|      |.|.....::.:..|.|.:|||     ...:
Mouse   154 DG--------------------SPLCCH------FHFSPKVMFTKVLKAQLWVYLR-----PVPR 187

  Fly   382 PG--LLEEIKKQP-------------RKDIVVTIHRAIRVANTTSFNPKVKMFEFRHSIPSGLGQ 431
            |.  .|:.::.:|             |:.|.:   |::::                 .:.|..|.
Mouse   188 PATVYLQILRLKPLTGEGTAGGGGGGRRHIRI---RSLKI-----------------ELHSRSGH 232

  Fly   432 WVAVDLKSLL--------GNLGSNMTQEILIKGAETWMKSLVVTTDNTSKNPLTVHIEIG-SQKK 487
            |.::|.|.:|        .|.|      |.|...:.....|.||:.......|...:|:. .:..
Mouse   233 WQSIDFKQVLHSWFRQPQSNWG------IEINAFDPSGTDLAVTSLGPGAEGLHPFMELRVLENT 291

  Fly   488 HRRKRSVYMDCTENDHDMRCCRYPLKVNFTSFGWHFVVAPTSFDAYFCSGDCKVGYLEQYPHTHL 552
            .|.:|::.:||.|:..:.|||||||.|:|.:|||.:::||..:.|.:|||.|:..::::||||||
Mouse   292 KRSRRNLGLDCDEHSSESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGQCEYMFMQKYPHTHL 356

  Fly   553 AALTT---SATPCCSPTKMSSLSLLYFDDNHNLVLSVIPNMSVEGCSCS 598
            .....   ||.|||:|||||.:::|||:|...::...||.|.|:.|.||
Mouse   357 VQQANPRGSAGPCCTPTKMSPINMLYFNDKQQIIYGKIPGMVVDRCGCS 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
myo	NP_726604.1	TGF_beta	506..597	CDD:278448	44/93 (47%)
Gdf11	NP_034402.1	TGFb_propeptide	59..283	CDD:279078	61/315 (19%)
		TGFB	311..405	CDD:214556	43/93 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	113	1.000	Domainoid score	I6128
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	159	1.000	Inparanoid score	I4237
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001977
OrthoInspector	1	1.000	-	-		otm43550
orthoMCL	1	0.900	-	-		OOG6_105895
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2472
SonicParanoid	1	1.000	-	-		X1292
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.890