Protein Alignment myo and Bmp6

DIOPT Version :10

• Sequence 1: NP_726604.1
• Gene: myo / 43811
• FlyBaseID: FBgn0026199
• Length: 598
• Species: Drosophila melanogaster
• Sequence 2: NP_031582.1
• Gene: Bmp6 / 12161
• MGIID: 88182
• Length: 510
• Species: Mus musculus
• Alignment Length: 445
• Identity: 93/445 - (20%)
• Similarity: 159/445 - (35%)
• Gaps: 142/445 - (31%)

  Fly   231 SVPQNIIDNFYRDYNASSKTTVWNRMESIDESHLSINDTYGDHIMTDFFDESSSSQMQGDDANTV 295
            |.|..::|.    |||.|..      :..|.:...:....|.|      ..:||||::.......
Mouse   129 SAPLFMLDL----YNALSND------DEEDGASEGVGQEPGSH------GGASSSQLRQPSPGAA 177

  Fly   296 NEFLIDLNKNQAKKSDI---------PINTNDE-----EYESILSHISSIYIFPEEIQPHVRHNR 346
            :    .||    :||.:         |:.:..:     :.:.::|.::.:. :.:|..||.||::
Mouse   178 H----SLN----RKSLLAPGPGGGASPLTSAQDSAFLNDADMVMSFVNLVE-YDKEFSPHQRHHK 233

  Fly   347 KVDVFRFQIDS-------------SYSDLSYATL--HLYLRGWDWISAHQPGLLEEIKKQPRKDI 396
            :   |:|.:..             .|.|....:.  ..:|     ||.:|  :|:|  .|.|...
Mouse   234 E---FKFNLSQIPEGEAVTAAEFRVYKDCVVGSFKNQTFL-----ISIYQ--VLQE--HQHRDSD 286

  Fly   397 VVTIHRAIRVANTTSFNPKVKMFEFRHSIPSGLGQWVAVDLKSLLGNLGSNMTQEILIKGAETWM 461
            :..:...:..|:...:      .||..:..|.|  ||.....    |:|..::
Mouse   287 LFLLDTRVVWASEEGW------LEFDITATSNL--WVVTPQH----NMGLQLS------------ 327

  Fly   462 KSLVVTTDNTSKNPLT------------------------VHIEIGSQKKHRRKRSVYMDCTEND 502
               |||.|....||..                        ||:........||::......|::.
Mouse   328 ---VVTRDGLHVNPRAAGLVGRDGPYDKQPFMVAFFKVSEVHVRTTRSASSRRRQQSRNRSTQSQ 389

  Fly   503 HDMR---------------CCRYPLKVNFTSFGWH-FVVAPTSFDAYFCSGDCKV---GYLEQYP 548
            ...|               |.::.|.|:|...||. :::||..:.|.:|.|:|..   .::....
Mouse   390 DVSRGSGSSDYNGSELKTACKKHELYVSFQDLGWQDWIIAPKGYAANYCDGECSFPLNAHMNATN 454

  Fly   549 H------THLAALTTSATPCCSPTKMSSLSLLYFDDNHNLVLSVIPNMSVEGCSC 597
            |      .||........|||:|||::::|:||||||.|::|....||.|..|.|
Mouse   455 HAIVQTLVHLMNPEYVPKPCCAPTKLNAISVLYFDDNSNVILKKYRNMVVRACGC 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
myo	NP_726604.1	TGF_beta_GDF8_like	506..597	CDD:381629	35/115 (30%)
Bmp6	NP_031582.1	TGFb_propeptide	58..359	CDD:459906	52/293 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	87..129		93/445 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	143..199		12/75 (16%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	370..402		4/31 (13%)
		TGF_beta_BMP6	408..510	CDD:381666	35/102 (34%)