DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment myo and Bmp3

DIOPT Version :9

Sequence 1:	NP_726604.1	Gene:	myo / 43811	FlyBaseID:	FBgn0026199	Length:	598	Species:	Drosophila melanogaster
Sequence 2:	NP_001297606.1	Gene:	Bmp3 / 110075	MGIID:	88179	Length:	470	Species:	Mus musculus

Alignment Length:	372	Identity:	82/372 - (22%)
Similarity:	127/372 - (34%)	Gaps:	100/372 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   267 NDTYGDHIMTDFFDESSSSQMQGD--------------DANTVNEF------------LIDLNKN 305
            :|...:|::..:...|.||::|..              ..|||..|            |...|..
Mouse    53 HDKVSEHMLWLYDRYSGSSRVQATRTPGSQLPGPQPLRGGNTVRSFRAAAAGTPQTKGLHTFNLT 117

  Fly   306 QAKKSDIPINTNDEEYESILSHISSIYIFPEEIQPHV-RHNRKVDVFRFQIDSSYSD----LSYA 365
            ...||:..::.....|...|.:||.....|:....|. |.:.::|:..:.:.|:.|.    ||..
Mouse   118 SLTKSENILSATLYFYVGELVNISLSCPEPQGCSHHTQRQHIQIDLSAWILKSNQSQLLGHLSVD 182

  Fly   366 TLHLYLRGWDWISAHQPGLLEEIKKQPRKDIVVTI-HRAIRVANTTSFNPK-------------- 415
            .:..|.....|:|.....||.:.|:.....|...| .||..:.....|.|:
Mouse   183 VVRPYRDSVSWLSKDITQLLRKAKQNEEFLIGFNITSRAHELPKRMLFFPEPYILVYANDAAISE 247

  Fly   416 ----VKMFEFRHSIPSGLGQWVAVDLKSLL----------GNLGSNMTQEILIKGAE-------T 459
                |...:......:|.|..:...::..|          |.|......|  :.|||       .
Mouse   248 PESVVSSLQRHRDFTAGTGPRLDSHVREALSVERRKKRSTGILLPLQNNE--LPGAEYQYKEEGA 310

  Fly   460 W-----MKSLVVTTDNTSKNP-----------LTVHIEIGSQKKHRRKRSVYMDCTENDHDMRCC 508
            |     .|||.......|:|.           .|:..:..:.||.|||:.|        ....|.
Mouse   311 WEERKPYKSLQTQPPEKSRNKKKQRKGSHQKGQTLQFDEQTLKKARRKQWV--------EPRNCA 367

  Fly   509 RYPLKVNFTSFGW-HFVVAPTSFDAYFCSGDCKVGYLEQYPHTHLAA 554
            |..|||:|...|| .::::|.||||::|||.|      |:|...:||
Mouse   368 RRYLKVDFADIGWSEWIISPKSFDAFYCSGAC------QFPMPKVAA 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
myo	NP_726604.1	TGF_beta	506..597	CDD:278448	21/50 (42%)
Bmp3	NP_001297606.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	29..53		82/372 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	314..349		6/34 (18%)
		TGF_beta	364..>424	CDD:278448	21/51 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010