Protein Alignment myo and mstn.1

DIOPT Version :9

• Sequence 1: NP_726604.1
• Gene: myo / 43811
• FlyBaseID: FBgn0026199
• Length: 598
• Species: Drosophila melanogaster
• Sequence 2: XP_002931568.1
• Gene: mstn.1 / 100496408
• XenbaseID: XB-GENE-483324
• Length: 369
• Species: Xenopus tropicalis
• Alignment Length: 420
• Identity: 110/420 - (26%)
• Similarity: 186/420 - (44%)
• Gaps: 112/420 - (26%)

  Fly   199 REKAKVDSIESIKMHILMRLNLKKLPNITK-------PISVP-QNIIDNFYRDYNASSKTTVWNR 255
            |:.:|...:|:||:.||.:|.|::.|||:|       |.:.| :.:||    .|:..|
 Frog    42 RQNSKSSRLEAIKLQILSKLRLEQAPNISKDAIKYLLPKAPPLEELID----QYDLQS------- 95

  Fly   256 MESIDESHLSINDTYGDHIMTDFFDESSSSQMQGDDANTVNEFLIDLNKNQAKKSDIPINTNDEE 320
                                    |:||...::.||.:...|.:|.:    ..:||   :|.:::
 Frog    96 ------------------------DDSSEGSLEEDDYHATTETIITM----PTESD---STGEKQ 129

  Fly   321 YESILSHISSIYIFPEEIQPHVRHNRKVDVFRFQIDSSYSDLSYATLHLYLRGWDWISAHQPGLL 385
                                      |...|:|.....|:.::.|.|.:||:
 Frog   130 --------------------------KCCYFKFSSVVQYNKIAKAQLWIYLK------------- 155

  Fly   386 EEIKKQPRKDIVVTIHRAIRVANTTSFNPKVKMFEFRHSIPSGLGQWVAVDLKSLLGN------- 443
               ..|.|..:.|...|..:..|..:.:..::..:.  .:..|.|.|.::|:|:.|.|
 Frog   156 ---PVQKRTTVFVQTFRLPKSLNDGARSTGIRTLKL--EMGPGSGTWKSLDVKTALQNWLKQPAS 215

  Fly   444 -LGSNMTQEILIKGAETWMKSLVVTTDNTSKNPLTVHIEIGSQKKHRRKRSVY-MDCTENDHDMR 506
             ||      |.||..:...:.|.:....::::.|...||:......:|.|..: :||.|:..:.|
 Frog   216 TLG------IEIKACDENGRDLPIAFRGSNEDGLNPFIEVKVMDTPKRSRRDFGLDCDEHSTESR 274

  Fly   507 CCRYPLKVNFTSFGWHFVVAPTSFDAYFCSGDCKVGYLEQYPHTHLAALTT---SATPCCSPTKM 568
            ||||||.|:|.:|||.:::||..:.|.:|||:|.:.:|::||||||.....   ||.|||:||||
 Frog   275 CCRYPLTVDFEAFGWDWIIAPKRYKANYCSGECGIVFLQKYPHTHLVQQANPRGSAGPCCTPTKM 339

  Fly   569 SSLSLLYFDDNHNLVLSVIPNMSVEGCSCS 598
            |.:::|||::|..::...||.|.|:.|.||
 Frog   340 SPINMLYFNENEQIIYGKIPAMVVDRCGCS 369

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
myo	NP_726604.1	TGF_beta	506..597	CDD:278448	45/93 (48%)
mstn.1	XP_002931568.1	TGFb_propeptide	36..236	CDD:366248	55/285 (19%)
		TGF_beta_GDF8	262..369	CDD:381658	48/106 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	114	1.000	Domainoid score	I5995
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H3850
Inparanoid	1	1.050	163	1.000	Inparanoid score	I4091
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001977
OrthoInspector	1	1.000	-	-		otm48710
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2472
SonicParanoid	1	1.000	-	-		X1292
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.990