Protein Alignment CG11360 and Mex3d

DIOPT Version :10

• Sequence 1: NP_651934.2
• Gene: CG11360 / 43810
• FlyBaseID: FBgn0039920
• Length: 628
• Species: Drosophila melanogaster
• Sequence 2: XP_006513682.1
• Gene: Mex3d / 237400
• MGIID: 2681847
• Length: 732
• Species: Mus musculus
• Alignment Length: 644
• Identity: 234/644 - (36%)
• Similarity: 301/644 - (46%)
• Gaps: 148/644 - (22%)

  Fly    30 MSEQSKVNESTLPLSDDPRTLQLALELSLVGFNDNQNCYAQPAQPLPMPLSARSDFEIGTINSTL 94
            |:..|.|....|||.|                        ....|.|.|....:.|        .
Mouse   174 MAVASSVAPGGLPLLD------------------------PDVSPRPSPPDVFASF--------A 206

  Fly    95 PIPSA--PNCLLLPNAGAVSSEDRSKKSQNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYI 157
            |.|:|  |:.||......:.|.   |||.||||||||||||||||||||||||||||||||||||
Mouse   207 PHPAALGPSTLLAEQLNVIGSR---KKSVNMTECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYI 268

  Fly   158 KTPVRGEEPVFVVTGRKEDVNKAKREILSAADHFSLIRASRKPVSDSQNNGMVGSTTSSGGGAVP 222
            |||||||||||:||||||||..|||||||||:|||||||:|     |:..|:.|:|
Mouse   269 KTPVRGEEPVFIVTGRKEDVEMAKREILSAAEHFSLIRATR-----SKAGGLSGAT--------- 319

  Fly   223 RMSGPPCMPGQVTIQVRVPYRVVGLVVGPKGATIKHIQQETQTYIVTPSREKEPIFEVTGLPDNV 287
              .|||.:|||.|||||||||||||||||||||||.|||.|.||||||.|:|||:|.|||:|:||
Mouse   320 --PGPPNLPGQTTIQVRVPYRVVGLVVGPKGATIKRIQQRTHTYIVTPGRDKEPVFAVTGMPENV 382

  Fly   288 DTARKQIEAHIALRTGSGSGSGDAITMQSSDSVDTKEY----ASL-----------PSLTQILND 337
            |.||::|||||.||||:.:.||......::.:....:.    |||           |:.|..|..
Mouse   383 DRAREEIEAHITLRTGAFTDSGPDSDFHANGTDVCLDLLGAAASLWAKAPHPGRRPPAATGGLRG 447

  Fly   338 DLNSEILSSIYKNSVPSTQEYANNSMKTVVNVSNSVKLVQGHHTG------------------NC 384
            |      :::...|.|......:.....:.:.|.|.......:.|                  :|
Mouse   448 D------NALGAASTPEPFYVGSRGGPPLPDPSPSSPYGGSGNGGFTFGGDGPSAPTGTATPEDC 506

  Fly   385 FQKSEFAEMEMTANITAADILDKRLPGNEVSVPLAKANVANIVFRTTSSKTLSFCPPTSTSASFH 449
            ....:|..:::|...||.           :..|..:|         ......|.||..:.:.:
Mouse   507 DFGFDFLALDLTVPATAT-----------IWAPFERA---------APLPAFSGCPAVNGAPA-- 549

  Fly   450 SNCNANILTRSCSSASSTTSTKSTNNSANTP-PEILNIWKSISDSIDVDEGIGDSPSIWNQPANI 513
               ..|..||..|...:.|:.:   :|...| |..|::...::.. .|.:.:|..|  |..|.:.
Mouse   550 ---QPNTGTRRSSGGGAATTPR---HSPTLPEPGGLSLELPLARR-SVPDPVGAVP--WRPPQSA 605

  Fly   514 IPTAHCSPTISISPT-----------DSLLGMGEHSANQQNLNHAKEPIMPNLPQKIKGIQVQSN 567
            :|....|.|.|.:|:           |::...|.|..:....|.:.....|..|.....
Mouse   606 LPPFSGSTTFSTTPSLPSTTLASSTLDTVPSEGNHKPSTTAANSSASTAAPGPPSAALA------ 664

  Fly   568 ADNFLTHRECFVCNENTVTTALVPCGHNMFCMECANHICLSMDAVCPVCNSIVYHAMRI 626
                   |||.||:|.....||||||||:|||:||..||...:..||.|.:....|:|:
Mouse   665 -------RECVVCSEGEAMAALVPCGHNLFCMDCAVRICGKSEPECPACRTPATQAIRV 716

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11360	NP_651934.2	KH-I_MEX3_rpt1	123..195	CDD:411851	67/71 (94%)
		KH-I_MEX3_rpt2	231..302	CDD:411852	56/70 (80%)
		PEX10	<515..621	CDD:227861	35/116 (30%)
		RING-HC_MEX3	575..627	CDD:438181	26/52 (50%)
Mex3d	XP_006513682.1	PHA03247	<27..215	CDD:223021	14/72 (19%)
		KH-I_MEX3_rpt1	234..306	CDD:411851	67/71 (94%)
		KH-I_MEX3_rpt2	326..397	CDD:411852	56/70 (80%)
		RING-HC_MEX3	665..716	CDD:438181	25/50 (50%)