Protein Alignment Slip1 and pdzrn4

DIOPT Version :10

• Sequence 1: NP_651933.1
• Gene: Slip1 / 43809
• FlyBaseID: FBgn0024728
• Length: 767
• Species: Drosophila melanogaster
• Sequence 2: NP_001076392.1
• Gene: pdzrn4 / 798289
• ZFINID: ZDB-GENE-041210-237
• Length: 788
• Species: Danio rerio
• Alignment Length: 878
• Identity: 202/878 - (23%)
• Similarity: 342/878 - (38%)
• Gaps: 297/878 - (33%)

  Fly    10 YVVLKINGYDIS---HLSRYEAVQKFLQSKETLVVEIRRQKHNALDLELKHGSNAKISKVDNPGE 71
            |.:.::||.:.|   |....||::     ||.:||::.|:..:::...|:     ::..||
Zfish    19 YEIAQVNGREFSKSGHDGTVEALR-----KEPIVVQVLRRGPSSVTQSLQ-----EVCVVD---- 69

  Fly    72 LSVLTDKSAEGTITAASASQQINCPSSTSLKEIETKTPVVLTLRARSHEDRLGSLQAASKETQTQ 136
            :...||.:.|..:..|...     ||:..:.:|   .|.:|:       |...|:|.
Zfish    70 VCTQTDITFEHIMALAKMR-----PSTPPVPDI---CPFLLS-------DSCHSIQT-------- 111

  Fly   137 SVVGTDVLKDNDLVNTITDNFIEHEHHLFEQCLE------------PEIDIEEVTLVKGVEQSSS 189
                                 :|||:.   .|.|            .|.:.|||.|.:   .:|.
Zfish   112 ---------------------MEHEYF---DCPEYVASTQADVDRAVEFECEEVELCR---MNSQ 149

  Fly   190 NQIGLIVTSSGIQQSSTDTNKGDILGNVLEHSEDVFISGVQPESIAYRDGRLRQGDQILRINGLD 254
            .::||.:.      ..||.          |....:|:..|:..|||.||||:|:||:||:|||.|
Zfish   150 EKLGLTLC------YRTDD----------EEDTAIFVGQVELNSIAARDGRIREGDRILQINGRD 198

  Fly   255 VKNQEELETQIA-RSSTSVTLLVSRILYPEDDDDEDIHFEYANTFLPDDYTNVVDKLDKVLLTHV 318
            |:|:||....:: .:|.|:.|||:|   ||...|        ..:|.:|:.:.:::|      .:
Zfish   199 VQNREEAVALLSNENSRSIVLLVTR---PEGQMD--------GNWLDEDHHDFLEEL------KM 246

  Fly   319 KSLEELSNKSAMQSDECYHIPEKNSSDSNVKISSLAKNIIEQ-STKSCSKIKLRPNANLDYKKKF 382
            :.|||...:..:|:..|..:..: ..|::...::.:.:|:|: |...||..:...:..|.|
Zfish   247 EILEEQKKEGILQTAGCMKLSTR-QEDASTDTATCSSSILEKDSGMKCSFEESSEHEFLSY---- 306

  Fly   383 NLPLSQEEVHLQYEYDESEHIYETIPEDSESEP-----------VYCSPYQRSNDKTSIGCSSPI 436
              |.:|::  |:..::.|.|:   :|.|:..|.           |.|..:|
Zfish   307 --PRTQKQ--LRDRWEASSHL---VPMDTMQEKKGQDNRLSENGVECDHFQ-------------- 350

  Fly   437 ASRPAESLERTMQQQTQRVAQWLGLKPQYQKTRQTLVGRPPPLKLVQQPTCSRVFTLRSTL-TNT 500
                                |.|.||.|.:...:                |..|:...||: .:.
Zfish   351 --------------------QLLELKCQIRNGGE----------------CGLVYRRSSTIECSL 379

  Fly   501 SASSSSGVAYSSY---------------------------------GQNNVVTGNAAAPGEEVD- 531
            :....||||...:                                 .:|.:..|..|...|..:
Zfish   380 TEQGGSGVARELHMLNEELRSIELECQSIMQAHQLRRSKHDSPRMDKENRLRRGKLADINEHPER 444

  Fly   532 ---------NSSSAYNTGDSNNSASPHQNTTNPDEA------IATGRKLDSTVIDSPNDHLDATG 581
                     :|||||||.:|:.| :|.....:||.:      :...|.|.|  :.||..
Zfish   445 LQSEKLRDKDSSSAYNTAESSRS-TPLGTEGSPDHSLQRRIHLTNQRNLRS--MQSPYS------ 500

  Fly   582 VSTMLLLPFGKS---GRIGLCSSNLPTAYV----------SERYTNVGSENEIHPLKSDIEILRV 633
             |.:|.||...|   .|....:|:.|....          |:.:::...::..:|.:||..:
Zfish   501 -SPILSLPSQSSSTCSRAHTYTSSTPPLQTPITSPGSQGPSQAFSSSLEQSPSNPSESDPAL--- 561

  Fly   634 KPTDDSYSHCP------------QFNAP---------NLSSYHFVSSQEVANRCHISTSLQKNAT 677
             |.||  ..|.            |:::|         ..|:.|:.|..::..: |.|:||:.:.:
Zfish   562 -PADD--ERCEKERNRNRLAAARQYHSPYHTSTTTTQPPSTRHYQSYLQLLQQ-HSSSSLEYSQS 622

  Fly   678 LLNGESAEEIP-------MVWKVKRRPDGTRYIVKRPVRNR--PQVALRKNMRYNEVTTTEDDTI 733
            .|:..|....|       :.||||.|.|||||:.:||.|:|  .:.|||.....:...||:||.:
Zfish   623 QLSLLSLRGRPGPSQAGRLEWKVKVRADGTRYVARRPARDRILRERALRIREERSGGMTTDDDAV 687

  Fly   734 SEVKIGRYWTKEERKRHIERAREKRHHQTQQQQ 766
            ||:|:||||:|||||:.:.||||:|..:...|:
Zfish   688 SELKMGRYWSKEERKQQLARAREQRRRREFMQK 720

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slip1	NP_651933.1	PDZ_canonical	<11..45	CDD:483948	10/36 (28%)
		PDZ_canonical	173..279	CDD:483948	37/106 (35%)
pdzrn4	NP_001076392.1	PDZ_canonical	<21..52	CDD:483948	10/35 (29%)
		PDZ2-PDZRN4-like	136..224	CDD:467200	38/109 (35%)