Protein Alignment Slip1 and Pdzrn4

DIOPT Version :10

• Sequence 1: NP_651933.1
• Gene: Slip1 / 43809
• FlyBaseID: FBgn0024728
• Length: 767
• Species: Drosophila melanogaster
• Sequence 2: NP_001101577.2
• Gene: Pdzrn4 / 315250
• RGDID: 1308860
• Length: 775
• Species: Rattus norvegicus
• Alignment Length: 820
• Identity: 198/820 - (24%)
• Similarity: 328/820 - (40%)
• Gaps: 207/820 - (25%)

  Fly    10 YVVLKINGYDISHLSRYEAVQKFLQSKETLVVEIRRQKHNALDLELKHGSNAKISKVDNPGELSV 74
            |.|.::||.|:|..:..|||:.|..:||.:||::.|:                 :.:..|.
  Rat    19 YEVSQVNGKDLSKATHEEAVEAFRTAKEPIVVQVLRR-----------------TPLSRPP---- 62

  Fly    75 LTDKSAEGTITAASASQQINCPSSTSLKEIETKTPVVLTLRARSHEDRLGSLQAASKETQTQSVV 139
             ...:.|..:..||....|......:|.::...||.|.........|...||....:.
  Rat    63 -YGMAPEVQLMNASTQTDITFEHIMALAKLRPLTPPVPDTCPFLLSDSCHSLHPMERA------- 119

  Fly   140 GTDVLKDNDLVNTITDNFIEHEHHLFEQCLEPEIDIEEVTLVKGVEQSSSNQIGLIVTSSGIQQS 204
               ..:|::.|:::..:....|          :.:.|||.|.:   .||..::||.|.      .
  Rat   120 ---FYEDHEYVSSLPADADRAE----------DFEYEEVELCR---VSSQEKLGLTVC------Y 162

  Fly   205 STDTNKGDILGNVLEHSEDVFISGVQPESIAYRDGRLRQGDQILRINGLDVKNQEELETQIARSS 269
            .||.          |....:::|.|.|.|||.:|||:|:||:||:|||.|::|:||....::...
  Rat   163 RTDD----------EEDTGIYVSEVDPNSIAAKDGRIREGDRILQINGEDIQNREEAVALLSSDE 217

  Fly   270 TS-VTLLVSRILYPEDDDDEDIHFEYANTFLPDDYTNVVDKLDKVLLTHVKSLEELSNKSAMQSD 333
            .. :.||::|   |:...||.        :|.|:....:::|:.      :.|||..|:.|..:.
  Rat   218 CKRIVLLIAR---PDLQLDEG--------WLEDERNEFLEELNS------EMLEEERNEGAQCTA 265

  Fly   334 ECYHIPEK------------NSSDSNVKISSLAK--------------NIIEQSTKSCSKIKLRP 372
            .....|:|            :||::..|.|.:.:              |::|:           |
  Rat   266 NELQQPKKQEEEEGTTDTATSSSNNQEKDSGVGRTDESLRNDESSEQENVVEE-----------P 319

  Fly   373 NANLDYKKKFNLPLSQEEV-HLQYEYDESEHIYETIPEDSESEPVYCSPYQ-------RSNDKTS 429
            ::.. .|.|..|..||:.: .::.:.::|....|.:..|..|....|..:|       |::....
  Rat   320 HSTA-LKSKRELGQSQDTLGSIELQCNQSCAGGECLDSDCASNQEVCEGFQQLLELKIRNHGDYD 383

  Fly   430 IGCSSPIASRPAESLERTMQQQTQRVAQWLGLKPQYQKTRQTLVGRPPPLKLVQQPTCSRVFTLR 494
            :..||       .:||....:|.       |::.:.:...:.|  |...|:........|:..:.
  Rat   384 LYYSS-------STLECNQGEQD-------GVEHELKLLNEEL--RNIELECQNIMQAHRLQKVT 432

  Fly   495 STLTNTSASSSSGVAYSSYG-----QNNVVTGNAAAPGEEVDNSSSAYNTGDSNNSASPHQNTTN 554
            ....:..|....|  :.:|.     |...:......|.:...:|||||||.:|
  Rat   433 DQYGDIWALHDGG--FRNYNTSLDMQRGKLDDIIEHPEKSDKDSSSAYNTAES------------ 483

  Fly   555 PDEAIATGRKLDSTVIDSPNDHLDATGVSTMLLLPFGKSGRIGLCSSNLPTAYVSERY--TNVGS 617
                   .|....||..||:..|     ..|:.|...|:.|..:.:...|:...:..|  |.|.:
  Rat   484 -------CRSTPLTVDRSPDSSL-----PRMINLTNKKNLRSMMTAHQSPSRPSTREYTATKVKT 536

  Fly   618 ENE---IHPLKSDIEILRVKPTDDSYSHCPQFNAPNLSSYHFVSSQEVANRCHISTSLQKNATLL 679
            .:|   :..|:..:|..::...:.:.|.    :.|.||.|| .||...||....:...|....|:
  Rat   537 THEGCSVESLEKSLENSQLLDQEHTVSE----HTPYLSPYH-SSSYRYANIPAHARHYQSYMQLI 596

  Fly   680 NGESA--------------EEIP------MVWKVKRRPDGTRYIVKRPVRNR--PQVALR-KNMR 721
            ..:||              :|.|      |.||||.|.||||||.|||||:|  .:.||: |..|
  Rat   597 QQKSAVEYAQSQLSLVSMCKESPRGSEPKMEWKVKIRSDGTRYITKRPVRDRLLKERALKIKEER 661

  Fly   722 YNEVTTTEDDTISEVKIGRYWTKEERKRHIERAREKRHHQ 761
            ..  .||:|||:||:|:||||:|||||:|:.||:|:|..:
  Rat   662 SG--MTTDDDTMSEMKMGRYWSKEERKQHLVRAKEQRRRR 699

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Slip1	NP_651933.1	PDZ_canonical	<11..45	CDD:483948	13/33 (39%)
		PDZ_canonical	173..279	CDD:483948	35/106 (33%)
Pdzrn4	NP_001101577.2	PDZ_canonical	<23..54	CDD:483948	12/30 (40%)
		PDZ2-PDZRN4-like	140..228	CDD:467200	36/109 (33%)