Protein Alignment Ekar and GLR3.4

DIOPT Version :10

• Sequence 1: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_172012.2
• Gene: GLR3.4 / 839268
• AraportID: AT1G05200
• Length: 959
• Species: Arabidopsis thaliana
• Alignment Length: 950
• Identity: 209/950 - (22%)
• Similarity: 376/950 - (39%)
• Gaps: 213/950 - (22%)

  Fly    20 PPLVRIGAIFSNQPGMYNSEL------AFRYAIHRLNMDKSLLPETTVDYYVEYVNRFDSFETVQ 78
            |..|.:||:|:     |:|.:      |.:.|:..:|.|:|:|....::...:..| ...|....
plant    58 PSSVNVGALFT-----YDSFIGRAAKPAVKAAMDDVNADQSVLKGIKLNIIFQDSN-CSGFIGTM 116

  Fly    79 KVCKLIRVGVQAVFSPTDSVLATHINSICDALDIPNIGRSAHD---------FSINVYPSKQLVN 134
            ...:|:...|.|...|..|.:|..|:.:.:.|.:|.:...|.|         :.:....:.....
plant   117 GALQLMENKVVAAIGPQSSGIAHMISYVANELHVPLLSFGATDPTLSSLQFPYFLRTTQNDYFQM 181

  Fly   135 YAFNDVIQYLNWTR-FGILHEKE---NGIINLHQLSRSFHGEVHMRQVSRDSYVSALNE-FKGKE 194
            :|..|.:.|..|.: ..|..:.|   |||        |..|:|..::.||.||.:|:.. .....
plant   182 HAIADFLSYSGWRQVIAIFVDDECGRNGI--------SVLGDVLAKKRSRISYKAAITPGADSSS 238

  Fly   195 IHNIIIDTN-------------SNGISIL-LKNILQQQMNEYKY---HYLFTSFD-LETYDLEDF 241
            |.::::..|             .:|:::. :...|....:.|.:   .:|.|:.| :|..|
plant   239 IRDLLVSVNLMESRVFVVHVNPDSGLNVFSVAKSLGMMASGYVWIATDWLPTAMDSMEHVD---- 299

  Fly   242 KYNFVNITSFRLVDTADVGVKQILKDIGLYSHHIF----KKPYLN--LHIKKSTILESEPALMFD 300
                        .||.|     :|:.:..:.|:..    |:.::.  .:::.:....|.....:|
plant   300 ------------SDTMD-----LLQGVVAFRHYTIESSVKRQFMARWKNLRPNDGFNSYAMYAYD 347

  Fly   301 SVYVFAIGLQT-LEQSHSLTLLN-----------ISCEEENSWDGGLSLINYLNAVEWKGLTGPI 353
            ||::.|..|.. ..:::::|..|           |.....:.::.|...:..:..:...|:||||
plant   348 SVWLVARALDVFFRENNNITFSNDPNLHKTNGSTIQLSALSVFNEGEKFMKIILGMNHTGVTGPI 412

  Fly   354 QF-KDGQRVQFKLDLIKLKQHSIVKVGEWTPHGHLNITEPSMFF----DAGSMNVTLVVI----T 409
            || .|..||....:::.|:..:...||.|:.|..|::..|...:    :..:.|..|..|    .
plant   413 QFDSDRNRVNPAYEVLNLEGTAPRTVGYWSNHSGLSVVHPETLYSRPPNTSTANQRLKGIIYPGE 477

  Fly   410 ILETP--YVMMHYGK-------------NFTGNER----FYGFCVDILETISREVGFDYILDLVP 455
            :.:.|  :|..:.||             ::...::    ..|:|:|:         |:..::|:|
plant   478 VTKPPRGWVFPNNGKPLRIGVPNRVSYTDYVSKDKNPPGVRGYCIDV---------FEAAIELLP 533

  Fly   456 ---DRKY-----GAKDPETGEWNGMVAQLMKYKADLAVGSMTITYARESVIDFTKPFMNLGISIL 512
               .|.|     |.::|   .::.:|.:::....|:|||.:||...|...:|||:||:..|:.::
plant   534 YPVPRTYILYGDGKRNP---SYDNLVNEVVADNFDVAVGDITIVTNRTRYVDFTQPFIESGLVVV 595

  Fly   513 --FKVPTSEPTRLFSFMNPLAIEIWIYVLIAYFLVSLCIYIVGKLSPIEWKCINACDLENISIGN 575
              .|...|.|   :||:.|..||:|......:..|...::|                ||: ....
plant   596 APVKEAKSSP---WSFLKPFTIEMWAVTGGFFLFVGAMVWI----------------LEH-RFNQ 640

  Fly   576 QF------SLTDSFWFTIGTFMQQSPDIYPRAMSTRIISSTWGFFSLIIVASYTANLAAFLTTER 634
            :|      .|...|||:..|......:....::. |.:...|.|..|||.:||||:|.:.||..:
plant   641 EFRGPPRRQLITIFWFSFSTMFFSHRENTVSSLG-RFVLIIWLFVVLIINSSYTASLTSILTIRQ 704

  Fly   635 MINPIENAEDLASQTEISYGTLDSGSTMTFFRDSVIETYKKIWRSMDNKKPSAFT-----TTYED 694
            :.:.||..:.|.:..| ..|..|.    ||.|:.:|...        |..||...     ..|..
plant   705 LTSRIEGIDSLVTSNE-PIGVQDG----TFARNYLINEL--------NILPSRIVPLKDEEQYLS 756

  Fly   695 GIKR-VNQGNYAFLMESTMLDYI----VQRDCNLTQIGGLLDTKGYGIATPKGSPWRDKISLAIL 754
            .::| .|.|..|.:::.  |.||    ...:|....:|......|:|.|..:.||....:|.|||
plant   757 ALQRGPNAGGVAAIVDE--LPYIEVLLTNSNCKFRTVGQEFTRTGWGFAFQRDSPLAVDMSTAIL 819

  Fly   755 ELQERGDIQMLYDKWWKNTDETCTRKNTSKQSKANSLGLESIGGVFVVLIAGIIVAAVVAFFEFW 819
            :|.|.|:::.::.||.....|...:.:.|:.|:   |.|:|..|:|  ||.||.....:..| ||
plant   820 QLSEEGELEKIHRKWLNYKHECSMQISNSEDSQ---LSLKSFWGLF--LICGITCFMALTVF-FW 878

  Fly   820 YNFRYNYEATPSQSVVNNKYNQDGILESER--NYTPPDRS 857
            ..| :.|:....:|.           :.||  ..:.|.||
plant   879 RVF-WQYQRLLPESA-----------DEERAGEVSEPSRS 906

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..390	CDD:380605	83/422 (20%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	100/417 (24%)
		Lig_chan	532..806	CDD:459656	73/289 (25%)
GLR3.4	NP_172012.2	PBP1_GABAb_receptor_plant	62..450	CDD:380645	83/422 (20%)
		Lig_chan-Glu_bd	507..591	CDD:463166	23/95 (24%)
		Lig_chan	613..867	CDD:459656	73/291 (25%)