Protein Alignment Ekar and ATGLR1.2

DIOPT Version :9

• Sequence 1: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_199651.1
• Gene: ATGLR1.2 / 834895
• AraportID: AT5G48400
• Length: 867
• Species: Arabidopsis thaliana
• Alignment Length: 870
• Identity: 164/870 - (18%)
• Similarity: 308/870 - (35%)
• Gaps: 214/870 - (24%)

  Fly    87 GVQAVFSPTDSVLATHINSICDALDIPNIGRSAH--------DFSINVYPSKQLVNYAFNDVIQY 143
            ||||:...         ||:.:|..:..:|..|.        ..|:::.....|:....|...:.
plant   104 GVQAIIGG---------NSLLEAKLLAELGEKARVPVISLNSPMSLSLSKYTHLIQATHNSASEV 159

  Fly   144 LNWTRF--G--------ILHEKENGIINLHQLSRSFH-GEVHMRQ-------VSRDSYVSALNEF 190
            ...|.|  |        :|.:.::...::|.:...|| ..||::.       .|.||.:..|.|.
plant   160 KGITAFLHGFDWNSVALVLEDHDDWRESMHFMVDHFHENNVHVQSKVAFSVTSSEDSLMDRLREL 224

  Fly   191 KGKEIHNIIIDTNSNGISILLKNILQQQ----------MNEYKYHYLFTSFDLETYDLEDFKYNF 245
            |         |..:....:.|..::..:          |.| .:.::.||     ..:..|...|
plant   225 K---------DLGTTVFVVHLSEVIATRLFPCAEKLGMMGE-GFAWILTS-----RSMSSFHDQF 274

  Fly   246 VNITSFRLVDTADVGVKQILKDIGLYSHHIFKKPYLNLHIKKSTILESEPA-------LMFDSVY 303
            ::    .|...|..||      :|..|:....|...|..::....|..|..       |....|:
plant   275 ID----DLTKEAMEGV------VGFKSYIPMSKELHNFTLRWRKTLPVEEVTGSEITRLSISGVW 329

  Fly   304 VFAIGLQTLEQSHSLTLLNISCEEENSWDGGLSLINYLNAVEWKGLTGPIQFKDGQRVQFKLDLI 368
            ...:.......:....:..::.          :|:..:....:|||:|..|..|.:.:..|.:::
plant   330 AHDVAWSLASAAEVTRMPTVTS----------TLLEAIKESRFKGLSGNFQLDDMKLLSDKFEIV 384

  Fly   369 KLKQHSIVKVGEWTPHG------HLNITEPSM-----------------FFDAGSMNVTLVVITI 410
            .:......:||.|..:|      .|:.|..::                 ..::|...:.::|.:.
plant   385 NMIGSGERRVGFWNSNGSFSNRRQLSSTHDNLETIIWPGGSAQSPKGRSLRESGRKKLRVLVTSS 449

  Fly   411 LETPYVMMHYGKNFTGNERFY-GFCVDILETISREVGFDYILDLVPDRKYGAKDPETGEW-NGMV 473
            ...|.:|.......|...... |||:::.:  :....|:|.::.:             .| ||..
plant   450 NRFPRLMKVETDPITHEITIVEGFCIEVFQ--ASIAPFNYEVEYI-------------RWLNGTN 499

  Fly   474 AQLMKY-------KADLAVGSMTITYARESVIDFTKPFMNLGISILFKVPTSEPTRLFSFMNPLA 531
            ...:.|       |.|.|||.:|||..|...:|||.|:..:|:.|:    .::...::.|..||.
plant   500 YTKLAYALHSQKDKYDAAVGDITITSDRSMYVDFTLPYTEMGLGIV----AAKERSMWVFFQPLT 560

  Fly   532 IEIWIYVLIAYFLVSLCIYIVGKLSPIEWKCINACDLENISIGNQFSLTDSFWFTIGTFMQQSPD 596
            ..:||.....:.|..:.::::.:....|::.         |...|..:.  .||...|.:....:
plant   561 PNLWITSAAFFVLTGIIVWLIERAENKEFQG---------SWPQQIGVV--IWFGFSTLVYAHRE 614

  Fly   597 IYPRAMSTRIISSTWGFFSLIIVASYTANLAAFLTTERM-INPIENAEDLASQTEISYGTLDSGS 660
            .....:| |.:.:.|.|..||:|.||||.|.:.:|.::: .|..|:.....|.:.|:...| :.|
plant   615 KLQHNLS-RFVVTVWVFAVLILVTSYTATLTSMMTVQQIRFNANEDYVGHLSGSLIANAAL-TNS 677

  Fly   661 TMTFFRDSVIETYKKIWRSMDNKKPSAFTT--TYEDGIKRVNQGNYAFLMESTMLDYIVQRDCNL 723
            ::...|...:.|.:...:::.||..|...:  .|...:...|.|:  |||..|.
plant   678 SLRAMRLLGLNTSEDYAQALMNKSVSYIVSELPYLKILLGENPGH--FLMVKTQ----------- 729

  Fly   724 TQIGGLLDTKGYGIATPKGSPWRDKISLAILELQERGDIQMLYDKWWK-----NTDETCTRKNTS 783
                  ..|.|:|....|||.....:|..|.:|:....:..:..:|:.     .||:|
plant   730 ------STTNGFGFMFQKGSELAPNVSREIAKLRTSERLNEMERRWFDKQLPYTTDDT------- 781

  Fly   784 KQSKANSLGLESIGGVFVVLIAGIIVAAVVAFF------EFW---------------YNFRYNYE 827
                :|.:.|....|:|  :|.|:..|..:|..      |.|               .:||..:.
plant   782 ----SNPITLYRFRGLF--MITGVSFAFALAVLLILWLRERWEILVNSVNIYFSQRLRHFRILFT 840

  Fly   828 AT--PSQSVVNNKYNQDGILESERN 850
            .|  ||...::|...::.:..::||
plant   841 RTIHPSPLGLDNPIGENAVQMAQRN 865

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..388	CDD:107377	59/349 (17%)
		ANF_receptor	39..371	CDD:279440	55/326 (17%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	81/380 (21%)
		Lig_chan	533..807	CDD:278489	58/281 (21%)
ATGLR1.2	NP_199651.1	PBP1_GABAb_receptor	41..407	CDD:107361	59/346 (17%)
		ANF_receptor	55..387	CDD:279440	55/326 (17%)
		GluR_Plant	440..770	CDD:270404	80/380 (21%)
		Lig_chan	563..801	CDD:278489	59/282 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	82	0.746	Domainoid score	I2907
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	1	1.000	-	-		mtm1027
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.910