Protein Alignment Ekar and GLR2.2

DIOPT Version :10

• Sequence 1: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_180048.1
• Gene: GLR2.2 / 817008
• AraportID: AT2G24720
• Length: 920
• Species: Arabidopsis thaliana
• Alignment Length: 841
• Identity: 179/841 - (21%)
• Similarity: 331/841 - (39%)
• Gaps: 190/841 - (22%)

  Fly    88 VQAVFSPTDSVLATHINSICDALDIPNIG-----------RSAHDFSINVYPSKQLVNYAFNDVI 141
            |:|:..|..|:.|..:..|.....:|.:.           ||.:.|......|.|:  :|...:|
plant    97 VKAILGPWTSMQAHFLIEIGQKSRVPVVSYSATSPSLTSLRSPYFFRATYEDSSQV--HAIKAII 159

  Fly   142 QYLNWTRFGILHEKENGIINLHQLSRSFHGEVHMRQVSRDSYVSALNEFKGKEIHNIIIDTNS-- 204
            :...|..          ::.:: :..:| ||..|.:::     .:|.:...:..:..:|..|:
plant   160 KLFGWRE----------VVPVY-IDNTF-GEGIMPRLT-----DSLQDINVRIPYRSVIPLNATD 207

  Fly   205 NGISILLKNILQQQMNEYKYHY---LFTSFDLETYDLEDFKYNFVNITSFRLVD----------- 255
            ..||:.|..::......:..|.   |.::..::..:|...|..:|.|.:..::|
plant   208 QDISVELLKMMNMPTRVFIVHMSSSLASTVFIKAKELGLMKPGYVWILTNGVMDGLRSINETGIE 272

  Fly   256 --TADVGVKQIL---KDIGLYSHHIFKK-PYLNLHIKKSTILESEPALMFDSVYVFAIGLQTLEQ 314
              ...:|:|..:   ||:..:.....:: |.:.|::......::..||   ::.:...|:..:..
plant   273 AMEGVLGIKTYIPKSKDLETFRSRWKRRFPQMELNVYGLWAYDATTAL---AMAIEDAGINNMTF 334

  Fly   315 SHSLTLLNISCEEENSWDG-GLS-----LINYLNAVEWKGLTGPIQFKDGQRVQFKLDLIKLKQH 373
            |:..|..|:|     ..|| |||     |:..::.|::|||.|...|..||......:::.:...
plant   335 SNVDTGKNVS-----ELDGLGLSQFGPKLLQTVSTVQFKGLAGDFHFVSGQLQPSVFEIVNMIGT 394

  Fly   374 SIVKVGEWT--------------------------------------PHG--------HLNITEP 392
            ....:|.||                                      |.|        .|.|..|
plant   395 GERSIGFWTEGNGLVKKLDQEPRSIGTLSTWPDHLKHIIWPGEAVSVPKGWEIPTNGKKLRIGVP 459

  Fly   393 SM--FFDAGSMNVTLVVITILETPYVMMHYGKNFTGNERFYGFCVDILETISREVGFDYILDLVP 455
            ..  |.|         ::.:...|         .|.:....|||:|..|.:.:.:.:|...:..|
plant   460 KRIGFTD---------LVKVTRDP---------ITNSTVVKGFCIDFFEAVIQAMPYDVSYEFFP 506

  Fly   456 DRKYGAKDPETGEWNGMVAQLMKYKADLAVGSMTITYARESVIDFTKPFMNLGISILFKVPTSEP 520
            ..|...:  ..|..|.:|.|:...:.|..||..||...|.|.:|||.|||..|:.::  ||..:.
plant   507 FEKPNGE--PAGNHNDLVHQVYLGQFDAVVGDTTILANRSSFVDFTLPFMKSGVGLI--VPLKDE 567

  Fly   521 TR--LFSFMNPLAIEIWIYVLIAYFLVSLCIYIVGKLSPIEWKCINACDLENISIGNQFSLTDSF 583
            .:  .|||:.||:||:|:..|:.:|||.:.::      .:|.: :|: |....:   .:..:..|
plant   568 VKRDKFSFLKPLSIELWLTTLVFFFLVGISVW------TLEHR-VNS-DFRGPA---NYQASTIF 621

  Fly   584 WFTIGTFMQQSPDIYPR----AMSTRIISSTWGFFSLIIVASYTANLAAFLTTERMINPIENAED 644
            ||...|.:     ..||    :...|.:..||.|..|::..||||:||:.||::: :||     .
plant   622 WFAFSTMV-----FAPRERVLSFGARSLVVTWYFVLLVLTQSYTASLASLLTSQQ-LNP-----T 675

  Fly   645 LASQTEISYGTLDSGSTMTFFRDSVIETYKKIWRSMDNKKPSA----FTTTYE--DGIKR--VNQ 701
            :.|.:.:    |..|.|:.:.|.|.|     :.:..:...|.:    |.|..|  :.:|:  .|.
plant   676 ITSMSSL----LHRGETVGYQRTSFI-----LGKLNETGFPQSSLVPFDTAEECDELLKKGPKNG 731

  Fly   702 GNYAFLMESTMLDYIVQRDCN-LTQIGGLLDTKGYGIATPKGSPWRDKISLAILELQERGDIQML 765
            |..|..:.:..:...:.:.|| ...:....:..|:|...|.|||....:|.|||::.|......|
plant   732 GVAAAFLGTPYVRLFLGQYCNTYKMVEEPFNVDGFGFVFPIGSPLVADVSRAILKVAESPKAVEL 796

  Fly   766 YDKWWKNTDETC----TRKNTSKQSKANSLGLESIGGVFVVLIAGIIVAAVVAFFEFWYNF 822
            ...|:|..:::|    |..:::....|..||:.|...:|:|    :.|..|:|..:|.:.|
plant   797 EHAWFKKKEQSCPDPVTNPDSNPTVTAIQLGVGSFWFLFLV----VFVVCVLALGKFTFCF 853

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..390	CDD:380605	65/386 (17%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	96/383 (25%)
		Lig_chan	532..806	CDD:459656	70/290 (24%)
GLR2.2	NP_180048.1	PBP1_GABAb_receptor_plant	33..412	CDD:380645	62/341 (18%)
		GluR_Plant	452..801	CDD:270404	100/401 (25%)