Protein Alignment Ekar and GLR2.3

DIOPT Version :10

• Sequence 1: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_001325281.1
• Gene: GLR2.3 / 817007
• AraportID: AT2G24710
• Length: 919
• Species: Arabidopsis thaliana
• Alignment Length: 852
• Identity: 195/852 - (22%)
• Similarity: 332/852 - (38%)
• Gaps: 221/852 - (25%)

  Fly    83 LIRVGVQAVFSPTDSVLATHINSICDALDIPNIGRSAHDFSINVYPSKQLVN-YAFNDVIQ-YLN 145
            ||.:| |....|..|..||  :.|..:|..|...|:.::.|..|.|.|.::. :.:.:|:. |::
plant   135 LIEIG-QKSRVPIVSYSAT--SPILTSLRSPYFLRATYEDSFQVQPIKAIIKLFGWREVVPVYID 196

  Fly   146 WTRFGILHEKENGII-NLHQLSRSFHGEVHMRQVSRDSYVSALNEFKGKEIHNIIIDTNSNGISI 209
            .| ||      .||: .|....:..:..:..|.|                   |.|:...:.||:
plant   197 NT-FG------EGIMPRLTDALQDINVRIPYRSV-------------------IAINATDHEISV 235

  Fly   210 -LLK--NILQQQMNEYKYHYLFTSFDLETYDLEDFKYNFVNITSFRLVD-------TADVGVKQI 264
             |||  |:..:....:.|:.|.:.|.::..:|...:..:|.|.:..::|       ||...::.:
plant   236 ELLKMMNMPTRVFLVHMYYDLASRFFIKAKELGLMEPGYVWILTNGVIDDLSLINETAVEAMEGV 300

  Fly   265 LKDIGLYSHHIFKKPYLNLHIKKSTILE---SEPALMFDSVYVFAIGLQTLEQSHSLTLLNISCE 326
            |.              :..:|.||..||   |....:|..|.:...||...:   :.|.|.::.|
plant   301 LG--------------IKTYIPKSPDLEKFRSRWRSLFPRVELSVYGLWAYD---ATTALAVAIE 348

  Fly   327 EENSWDG------------------GLS-----LINYLNAVEWKGLTGPIQF------------- 355
            |..:.:.                  |||     |:..|..|:::||.|..:|
plant   349 EAGTNNMTFSKVVDTGRNVSELEALGLSQFGPKLLQTLLTVQFRGLAGEFRFFRGQLQPSVFEIV 413

  Fly   356 -------------KDGQRVQFKLD--------LIKLKQH--SIVKVGE-------W---TPHGHL 387
                         |:|..:..|||        |...|.|  .||..||       |   |....|
plant   414 NIINTGEKSIGFWKEGNGLVKKLDQQASSISALSTWKDHLKHIVWPGEADSVPKGWQIPTKGKKL 478

  Fly   388 NITEPSM--FFDAGSMNVTLVVITILETPYVMMHYGKNFTGNERFYGFCVDILETISREVGFDYI 450
            .|..|..  :.|         ::.:...|         .|.:....|||:|..|.:.||:.:|..
plant   479 RIGVPKRTGYTD---------LVKVTRDP---------ITNSTVVTGFCIDFFEAVIRELPYDVS 525

  Fly   451 LDLVPDRKYGAKDPETGEWNGMVAQLMKYKADLAVGSMTITYARESVIDFTKPFMNLGISILFKV 515
            .:.:|..|...|  ..|.:|.:|.|:...:.|..||..||...|.|.:|||.||:..|:.::  |
plant   526 YEFIPFEKPDGK--TAGNYNDLVYQVYLGRYDAVVGDTTILVNRSSYVDFTFPFIKSGVGLI--V 586

  Fly   516 PTSEPTR--LFSFMNPLAIEIWIYVLIAYFLVSLCIYIVG-KLSPIEWKCINACDLENISIGNQF 577
            ..::|.:  ...||.||:.::|:...|::|||...::::. |.:|            :.|...:|
plant   587 EMTDPVKRDYILFMKPLSWKLWLTSFISFFLVGCTVWVLEYKRNP------------DFSGPPRF 639

  Fly   578 SLTDSFWFTIGTFMQQSPDIYPR----AMSTRIISSTWGFFSLIIVASYTANLAAFLTTERMINP 638
            ..:...||...|.:     ..||    :...|.:...|.|..|::..||||:||:.||::: :||
plant   640 QASTICWFAFSTMV-----FAPRERVFSFWARALVIAWYFLVLVLTQSYTASLASLLTSQK-LNP 698

  Fly   639 IENAEDLASQTEISYGTLDSGSTMTFFRDSVIETYKKIWRSMDNKKPSAFT-------TTYEDGI 696
                 .:.|.:.:    |:.|.|:.:.|.|.|         :...|...|.       .|.|:..
plant   699 -----TITSMSSL----LEKGETVGYQRTSFI---------LGKLKERGFPQSSLVPFDTAEECD 745

  Fly   697 KRVNQG------NYAFLMESTMLDYIVQRDCN-LTQIGGLLDTKGYGIATPKGSPWRDKISLAIL 754
            :.:::|      :.||| |...|...:.:.|| ...:....:..|:|...|.|||....:|.|||
plant   746 ELLSKGPKKGGVSGAFL-EIPYLRLFLGQFCNTYKMVEEPFNVDGFGFVFPIGSPLVADVSRAIL 809

  Fly   755 ELQERGDIQMLYDKWWKNTDETC----TRKNTSKQSKANSLGLESIGGVFVVLIAGIIVAAVVAF 815
            ::.|......|...|:|..:::|    |..:.:....:..|.::|    |:.|..|:::..|:|.
plant   810 KVAESPKAMELERAWFKKKEQSCPDPITNPDPNPSFTSRQLDIDS----FLFLFVGVLLVCVMAL 870

  Fly   816 FEFWYNF 822
            ..|.|.|
plant   871 GNFTYCF 877

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..390	CDD:380605	83/391 (21%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	96/389 (25%)
		Lig_chan	532..806	CDD:459656	67/296 (23%)
GLR2.3	NP_001325281.1	PBP1_GABAb_receptor_plant	69..436	CDD:380645	70/346 (20%)
		GluR_Plant	476..825	CDD:270404	99/407 (24%)
		Lig_chan	604..865	CDD:459656	68/301 (23%)