Protein Alignment Ekar and GLR2

DIOPT Version :9

• Sequence 1: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_001318239.1
• Gene: GLR2 / 816231
• AraportID: AT2G17260
• Length: 925
• Species: Arabidopsis thaliana
• Alignment Length: 937
• Identity: 210/937 - (22%)
• Similarity: 382/937 - (40%)
• Gaps: 183/937 - (19%)

  Fly     1 MLIASGFLLFQFLSYGLGVPPLVRIGAIFSNQPGMY--NSELAFRYAIHRLNMDKSLLPETTVDY 63
            :::..|.||.:..|...  ||::::||||.... ||  .:.:||:.|...:|.|.|.|..:.:..
plant    14 IVLGGGLLLSEGASSSR--PPVIKVGAIFGLNT-MYGETANIAFKAAEEDVNSDPSFLGGSKLRI 75

  Fly    64 YVEYVNRFDSFETVQKVCKLIRVGVQAVFSPTDSVLATHINSICDALDIPNIGRSAHD------- 121
            .:....| ..|.::....:.:...|.|:..|..|::|..::.:.:.|.:|.:..:|.|
plant    76 LMNDAKR-SGFLSIMGALQFMETDVVAIIGPQTSIMAHVLSHLANELTVPMLSFTALDPTLSPLQ 139

  Fly   122 --FSINVYPSKQLVNYAFNDVIQYLNWTRFGILHEKE----NGIINLHQLSRSFHGEVHMRQV-- 178
              |.:...||...:..|..::|.|..|:....|:..:    ||:..|.........::..:.|
plant   140 FPFFVQTAPSDLFLMRAIAEMITYYGWSDVVALYNDDDNSRNGVTALGDELEERRCKISYKAVLP 204

  Fly   179 ------SRDSYVSALNEFKGKEIHNIIIDTNSNGISILLKNILQQQMNEYKYHYLFTSFDLETYD 237
                  |....:..|.:.:|.|...|:::|..|...::.|...:..|.|..|.::.|::.....|
plant   205 LDVVITSPVEIIEELIKIRGMESRVIVVNTFPNTGKMIFKEAERLGMMEKGYVWIATTWLSSVLD 269

  Fly   238 LE---DFKYNFVN-ITSFRLVDTADVGVKQIL-----------KDIGLYSHHIFKKPYLNLHIKK 287
            ..   |.|  .|| :.:.|| .|.|...|:..           |.|||..:.::
plant   270 SNLPLDTK--LVNGVLTLRL-HTPDSRKKRDFAARWKNKLSNNKTIGLNVYGLY----------- 320

  Fly   288 STILESEPALMFDSVYVFAIGLQT-LEQSHSLTLLN-----------ISCEEENSWDGGLSLINY 340
                      .:|:|::.|..::| ||...:|:..|           ::....:.:|.|..|::|
plant   321 ----------AYDTVWIIARAVKTLLEAGGNLSFSNDAKLGSLKGEALNLSALSRFDQGSQLLDY 375

  Fly   341 LNAVEWKGLTGPIQF-KDGQRVQFKLDLIKLKQHSIVKVGEWTPHGHLNITEPSMFF----DAGS 400
            :...:..|||||:|| .|...:|...|:|.|....:.::|.|:.:..|:|..|..|:    :..|
plant   376 IVHTKMSGLTGPVQFHPDRSMLQPSYDIINLVDDRVHQIGYWSNYSGLSIVPPESFYSKPPNRSS 440

  Fly   401 MNVTLVVIT------ILETPYVMMHYG-------------KNFT-----GNERFYGFCVDILET- 440
            .|..|..:|      :....::..:.|             |:|.     .:.:..|:|:|:.|.
plant   441 SNQHLNSVTWPGGTSVTPRGWIFRNNGRRLRIGVPDRASFKDFVSRVNGSSNKVQGYCIDVFEAA 505

  Fly   441 ---ISREVGFDYIL--DLVPDRKYGAKDPETGEWNGMVAQLMKYKADLAVGSMTITYARESVIDF 500
               :|..|..::|.  |       |..:|...|....|...:.:  |..||.:.|...|..::||
plant   506 VKLLSYPVPHEFIFFGD-------GLTNPNYNELVNKVTTGVDF--DAVVGDIAIVTKRTRIVDF 561

  Fly   501 TKPFMNLGISILFKVPTSEPTRL----FSFMNPLAIEIWIYVLIAYFLVSLCIYIVGKLSPIEWK 561
            |:|::..|:.::..|     |||    ::|:.|..:.:|......:.:|...|:|
plant   562 TQPYIESGLVVVAPV-----TRLNENPWAFLRPFTLPMWAVTASFFVIVGAAIWI---------- 611

  Fly   562 CINACDLENISIGNQF------SLTDSFWFTIGTFMQQSPDIYPRAMST--RIISSTWGFFSLII 618
                  ||: .|.::|      .:....|||..|......:   ..:||  |::...|.|..|||
plant   612 ------LEH-RINDEFRGPPRRQIITILWFTFSTMFFSHRE---TTVSTLGRMVLLIWLFVVLII 666

  Fly   619 VASYTANLAAFLTTERMINPIENAEDLASQTEISYGTLDSGSTMTFFRDSVIETYKKIWRSMDNK 683
            .:||||:|.:.||.:::.:||:..:.|.|.|          ..:.|...|..|.|.....::.:.
plant   667 TSSYTASLTSILTVQQLNSPIKGVDTLISST----------GRIGFQVGSFAENYMTDELNIASS 721

  Fly   684 K--PSAFTTTYEDGIKRVNQGNYAFLM-ESTMLDYIVQRDCNLTQIGGLLDTKGYGIATPKGSPW 745
            :  |.|....|.:.::   .|..|.:: |...:|..:...|.....|......|:|.|.|:.||.
plant   722 RLVPLASPEEYANALQ---NGTVAAIVDERPYIDLFLSDYCKFAIRGQEFTRCGWGFAFPRDSPL 783

  Fly   746 RDKISLAILELQERGDIQMLYDKWWKNTDETCTRKNTSKQSKANSLGLESIGGVFVVLIAGIIVA 810
            ...:|.|||.|.|.|::|.::|:|...::  |:..:.|:...:..|.:.|..|:|:|:....:||
plant   784 AVDMSTAILGLSETGELQKIHDRWLSKSN--CSSPHGSQSGDSEQLNVHSFWGMFLVVGIACLVA 846

  Fly   811 AVVAFFEFWYNFRYN------YEATPS 831
            ..:.||:...:|..:      .||.||
plant   847 LFIHFFKIIRDFCKDTPEVVVEEAIPS 873

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..388	CDD:107377	88/414 (21%)
		ANF_receptor	39..371	CDD:279440	79/380 (21%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	95/413 (23%)
		Lig_chan	533..807	CDD:278489	68/284 (24%)
GLR2	NP_001318239.1	PBP1_GABAb_receptor	35..424	CDD:107361	88/414 (21%)
		GluR_Plant	468..808	CDD:270404	90/386 (23%)
		Lig_chan	594..843	CDD:306551	68/283 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	82	0.746	Domainoid score	I2907
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	164	1.000	Inparanoid score	I1601
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	1	1.000	-	-		mtm1027
orthoMCL	1	0.900	-	-		OOG6_100167
Panther	1	1.100	-	-	O	PTHR18966
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.860