Protein Alignment Ekar and grin3ba

DIOPT Version :9

• Sequence 1: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: XP_021323058.1
• Gene: grin3ba / 566411
• ZFINID: ZDB-GENE-070912-354
• Length: 1118
• Species: Danio rerio
• Alignment Length: 666
• Identity: 166/666 - (24%)
• Similarity: 277/666 - (41%)
• Gaps: 140/666 - (21%)

  Fly   268 IGLYSH-HIFKKPYLNLHIK-----------KSTILESEPALMFDSVYVFAIGLQTLEQSHSLTL 320
            :||.:: .:.:|| ||.:|:           .:|::..:.||:.:.|..|     .....|.|.
Zfish   299 LGLMAYGEVNRKP-LNFYIRDTLQLIGRAVYAATMVRPDLALIQNMVNCF-----DKPNKHELP- 356

  Fly   321 LNISCEEENSWDGGLSLINYLNAVEWKGLTGPIQFK-------DGQRVQ-FKLDLIKLKQHSIVK 377
                       ..|..|..:|:...:.|||||::.:       ..||.. :.|....|.|.|.|.
Zfish   357 -----------SSGQYLARFLSNTSFTGLTGPVRVERSFSRVLTSQRFHIWSLQRDPLGQPSWVT 410

  Fly   378 VGEWTPHGHLNITEPSMF-------------------FDAG--SMNVTLVVITILETPYVMM--- 418
            |..| ..|.|.:.|..::                   :.||  .....|.|:|::|.|:|..
Zfish   411 VASW-QSGRLELEEQGLWPGVTQHQREDGPGIRLGGRWQAGLPVAGSRLRVVTLVEHPFVFTREV 474

  Fly   419 -HYGKNFTG--------------NERF-------------------YGFCVDILETISREVGFDY 449
             ..|:...|              |:.|                   ||:|:|:||.::.::.|::
Zfish   475 DEEGQCPAGQLCLDPQTNNSEVLNQLFRELEQTNSSSLPTDMRKCCYGYCIDLLEKLAEDMHFEF 539

  Fly   450 ILDLVPDRKYGAKDPETGEWNGMVAQLMKYKADLAVGSMTITYARESVIDFTKPFMNLGISILFK 514
            .|.:|.|.||||.  :.|.|:|:|..|:...||:||.|.:|..||..|||||.||.:..:.||.:
Zfish   540 DLYIVGDGKYGAW--KGGRWSGLVGDLLSGVADMAVTSFSINSARSRVIDFTSPFFSTSLGILVR 602

  Fly   515 -VPTSEPTRLFSFMNPLAIEIWIYVLIAYFLVSLCIYIVGKLSPIEWKCINACDLENISIGNQFS 578
             ..|:.|  :.:||.||...:|:.:.:|..:.:|.|.:....||..........:...|..:..:
Zfish   603 SKDTAAP--IGAFMWPLHWSMWVGIFVALHITALFITLYEWNSPFGMTPHGRNRIRVFSYSSALN 665

  Fly   579 LTDSFWF--TIGTFMQQSPDIYPRAMSTRIISSTWGFFSLIIVASYTANLAAFLTTERMINPIEN 641
            |..:..|  |:.:..       |:..:.|.:.:.|..|.|::::||||||||.:..|:....:..
Zfish   666 LCYAILFGRTVASKT-------PKCWTGRFLMNLWAIFCLLVLSSYTANLAAVMVGEKTFEEVSG 723

  Fly   642 AEDLA---SQTEISYGTLDSGSTMTFFRDSVIETYKKIWRSMDNKKPSAFTTTYEDGIKRVNQGN 703
            ..|:.   ......:||:...|...:.:.|..|.::.:.|.   .||     |..||:..:....
Zfish   724 IHDVKLHHPSLGFRFGTVRESSAEDYVKKSFPEMHEYMRRF---NKP-----TTPDGVSTLKTDP 780

  Fly   704 ---YAFLMESTMLDY--IVQRDCNLTQIGGLLDTKGYGIATPKGSPWRDKISLAILELQERGDIQ 763
               .||:|:..:|||  .:..||.|..:|.....:||||..|:.||....:|..:...:..|.:.
Zfish   781 PQLDAFIMDKALLDYEVSIDADCKLLTVGKPFAIEGYGIGLPQNSPLTRNVSEYVSRYKSDGYMD 845

  Fly   764 MLYDKWWKNTDETCTRKNTSKQSKANSLGLESIGGVFVVLIAGIIVAAVV-----AFFEF----- 818
            ||:|||:|..  .| .|.....::...:|::...|:||:|..|:..|.:.     |||.|
Zfish   846 MLHDKWYKVV--PC-GKRVFAVTETLQMGIQHFSGLFVLLCVGVAGALLTLLGEHAFFRFILPHL 907

  Fly   819 WYNFRYNYEATPSQSV 834
            .:..|:.|....||.:
Zfish   908 RHQQRFKYWLHTSQKI 923

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..388	CDD:107377	32/139 (23%)
		ANF_receptor	39..371	CDD:279440	25/122 (20%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	112/416 (27%)
		Lig_chan	533..807	CDD:278489	68/283 (24%)
grin3ba	XP_021323058.1	Periplasmic_Binding_Protein_Type_1	26..428	CDD:324556	34/147 (23%)
		PBP2_iGluR_NMDA_Nr3	457..852	CDD:270438	111/413 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170591828
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740