Protein Alignment Ekar and grin2da

DIOPT Version :10

• Sequence 1: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: XP_073787594.1
• Gene: grin2da / 449864
• ZFINID: ZDB-GENE-041008-124
• Length: 1918
• Species: Danio rerio
• Alignment Length: 502
• Identity: 138/502 - (27%)
• Similarity: 247/502 - (49%)
• Gaps: 89/502 - (17%)

  Fly   377 KVGEWTPHGHLNITEP-----SMFFDAGSMNVTLVVITILETPYVMMHYGKNFTG---------- 426
            :|| |..:|.|.:..|     ..|......:..|.|:|:.|.|:|::......||
Zfish   423 EVG-WWENGVLRLRYPPWSRYGPFLKPLDDSQHLRVVTLEERPFVIVEPADPGTGSCIRDSVPCR 486

  Fly   427 ---NER--------------FYGFCVDILETISREVGFDYILDLVPDRKYGAKDPETGEWNGMVA 474
               |.|              ..|||:|:|:.:::.|||.|.|.||.:.::| |:.: |:|||||.
Zfish   487 LPLNNRSSMVVEGIQSMKHCCKGFCIDVLKRLAKIVGFTYDLYLVTNGRHG-KNID-GQWNGMVG 549

  Fly   475 QLMKYKADLAVGSMTITYARESVIDFTKPFMNLGISILFKVP--TSEPTRLFSFMNPLAIEIWIY 537
            :::..:||:|:||:||...|..|::|:.||:..|||::....  |..|:   :|:.|.:..:|:.
Zfish   550 EVVSKRADMAIGSLTINEERSEVVEFSVPFVETGISVMVSRSNGTVSPS---AFLEPYSPAVWVM 611

  Fly   538 VLI-AYFLVSLCIYIVGKLSPIEWKCINACDLENISI-------GNQFSLTDSFWFTIG-TFMQQ 593
            :.: ...:|::.::|....||:.:         |.|:       |::|::..|.|.... .|...
Zfish   612 MFVMCLSVVAVTVFIFEFFSPVGY---------NRSLQSGKTAGGSKFTIGKSIWLLWALVFNNS 667

  Fly   594 SPDIYPRAMSTRIISSTWGFFSLIIVASYTANLAAFLTTERMINPIENAEDLASQ--TE----IS 652
            .|...||..:::|:...|.||::|.:||||||||||:..|..|:.:....|...|  ||    :.
Zfish   668 VPVENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEEYIDTVSGLSDKKFQHPTEQYPPLR 732

  Fly   653 YGTLDSGSTMTFFRDSVIETYKKIWRSM--DNKKPSAFTTTYEDGIKRVNQGNY-AFLMESTMLD 714
            :||:.:|||    .:::...|..:.:.|  :|::      ..||.|:.:..|.. ||:.::.:|:
Zfish   733 FGTVPNGST----EENIRSNYPNMHQYMVRNNQR------GVEDAIENLKTGKLDAFIYDAAVLN 787

  Fly   715 YIVQRD--CNLTQIGG--LLDTKGYGIATPKGSPWRDKISLAILELQERGDIQMLYDKWWKNTDE 775
            |:.::|  |.:..||.  :..|.|||:|..|.|.|:..:.||:|:|....:|.||...|...
Zfish   788 YMARKDEGCKVMTIGSGKVFATTGYGVALHKNSRWKRPLDLALLQLVGDDEIDMLERLWLSG--- 849

  Fly   776 TCTRKNTSKQSKANSLGLESIGGVFVVLIAGIIVAAVVAFFE---FW 819
            .|  .|...:..::.|.::::.|||.:|:..:.::.:|..:|   :|
Zfish   850 IC--HNDKIEVMSSKLDIDNMAGVFYMLLVAMGLSLLVFAWEHLVYW 894

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..390	CDD:380605	5/12 (42%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	121/419 (29%)
		Lig_chan	532..806	CDD:459656	79/295 (27%)
grin2da	XP_073787594.1	None