Protein Alignment Ekar and Ir8a

DIOPT Version :9

• Sequence 1: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_727328.1
• Gene: Ir8a / 31867
• FlyBaseID: FBgn0052704
• Length: 936
• Species: Drosophila melanogaster
• Alignment Length: 950
• Identity: 213/950 - (22%)
• Similarity: 388/950 - (40%)
• Gaps: 238/950 - (25%)

  Fly    61 VDYYVEYVNRFDSFET----VQKVCKLIRVGVQ---AVFSPTDSVLATHINSICDALDIPNIGRS 118
            :.:::|.|.|.: |:|    |.|....:|:.|:   ...:.|.|.....:...|:.|.  .:|.|
  Fly    22 ITFWIEPVQRAE-FDTDIAMVLKELDALRLDVKVDDTTLTLTRSEDGLDMQRFCEILS--TVGAS 83

  Fly   119 AHDFSINVYPSKQLVNYAFNDVIQYLNWTR-FGILHEKENGIINLHQLSRSF---HGEVHMRQV- 178
            |            :::      :.|.:|.. :.::.....|.:.|.::.|.|   .|: .|||.
  Fly    84 A------------VID------LTYSHWEEGYNLVRSLGIGYVRLERIMRPFLDMFGD-FMRQKR 129

  Fly   179 ----------SRDSYVSALNEFKGKEIHNIIIDTNS----------------------------- 204
                      :||:..:......|.....:|:|.:.
  Fly   130 ANNVAMVFMNARDAVEAMQQMLVGYPFRTLIMDASQTDPGQHFLERIRSLRPAPTYIALFARAAA 194

  Fly   205 -NGI--SILLKNILQQQMNEYKYHYLFTSFDLETYDLEDFKY--NFVNITSFRLVDTADVGVKQI 264
             |||  .:...::.|:.:   ::|::|    |:|.| ..|||  .....|.|.|...| :.....
  Fly   195 MNGIFEKVQKADLFQRPL---EWHFVF----LDTRD-RVFKYRRQAELCTRFTLNPRA-ICRSMP 250

  Fly   265 LKDIGLYSHHIFKKPYLNLHIKKSTILESEPALMFDSVYVFAIGLQTLEQSHSLTLLNISCEEEN 329
            :.|:...|....::..| |::.:|.|    .|......|..|| .|....:.|.:.::...|:::
  Fly   251 MPDLYCGSGFTMQRAML-LNVLRSLI----NAAQVSPGYPLAI-YQDCNATASSSEVSDPLEKDD 309

  Fly   330 SWDGGLSLINYLNAVEWK---------------------GLTGPIQFKDG---QRVQFKLDLIKL 370
                    .|:|:.|.|.                     |||..:....|   ...:.|.||
  Fly   310 --------YNWLDMVHWSNFLAYAPPLPHIQDQFQSPVPGLTFAVNISAGYYSSEHEAKTDL--- 363

  Fly   371 KQHSIVKVGEWTPHGHLNITEPSM-----FFDAGSMNVTLVVITILETPYVMMHYG-----KNFT 425
                    ..|:..|.:.:...::     ||..|:..       .:...|:....|     ::.:
  Fly   364 --------AAWSSVGEMRLLNETISPARRFFRIGTAE-------SIPWSYLRREEGTGELIRDRS 413

  Fly   426 GNERFYGFCVDILETISREVGFDYILDLVPDRKYGAKDPETGEWNGMVAQLMKYKADLAVGSMTI 490
            |...:.|:|:|.:..:|:::.|::.: :.|:..:..:..|.|||:|:|..|::.:.|.|:.::.:
  Fly   414 GLPIWEGYCIDFIIRLSQKLNFEFEI-VAPEVGHMGELNELGEWDGVVGDLVRGETDFAIAALKM 477

  Fly   491 TYARESVIDFTKPFM-NLGISILFKVPTSEPTRLFSFMNPLAIEIWIYVLIAYFLVSLCIYIVGK 554
            ...||.||||..|:. ..||||..:.|... |.||.||..|.:|:|:.::.|....::.|:.:.|
  Fly   478 YSEREEVIDFLPPYYEQTGISIAIRKPVRR-TSLFKFMTVLRLEVWLSIVAALVGTAIMIWFMDK 541

  Fly   555 LSPIEWKCIN-------ACDLENISIGNQFSLTDSFWFTIGTFMQQSPDIYPRAMSTRIISSTWG 612
            .||  :...|       ||        .:|:|.:||||.:.:|..|.....|:|:|.|::.:.:.
  Fly   542 YSP--YSSRNNRQAYPYAC--------REFTLRESFWFALTSFTPQGGGEAPKAISGRMLVAAYW 596

  Fly   613 FFSLIIVASYTANLAAFLTTERMINPIENAEDLASQTEISYGTLDSGST------MTFFRDSVIE 671
            .|.::::|::|||||||||.|||..|:::.|.||.|:.|:|..:....|      |.|..|::..
  Fly   597 LFVVLMLATFTANLAAFLTVERMQTPVQSLEQLARQSRINYTVVKDSDTHQYFVNMKFAEDTLYR 661

  Fly   672 TYK-------------KIW------------RSMDNKKPSAFTTTYEDGIKRVN---QGNYAFLM 708
            .:|             :||            .::::.:|.|   ..::|...|:   ..:|||:.
  Fly   662 MWKELALNASKDFKKFRIWDYPIKEQYGHILLAINSSQPVA---DAKEGFANVDAHENADYAFIH 723

  Fly   709 ESTMLDYIVQRDCNLTQIGGLLDTKGYGIATPKGSPWRDKISLAILELQERGDIQMLYDKWWKNT 773
            :|..:.|.:.|:||||::|.:...:.|.:|..:||...|::|.||||||:....:.|..|:|..:
  Fly   724 DSAEIKYEITRNCNLTEVGEVFAEQPYAVAVQQGSHLGDELSYAILELQKDRFFEELKAKYWNQS 788

  Fly   774 DETCTRKNTSKQSKANSLGLESIGGVFVVLIAGIIVAAVVAFFE-FWYNFRYNYEATPSQSVVNN 837
            :    ..|.........:.|||:||||:..:.|:::|.:....| .:|..:.|.........||:
  Fly   789 N----LPNCPLSEDQEGITLESLGGVFIATLFGLVLAMMTLGMEVLYYKKKQNALEITQVRPVND 849

  Fly   838 KYNQDG--------------------ILESER---NYTPP 854
            .....|                    :||:|.   ..:||
  Fly   850 SSGSGGNSSTAPPTATSTTKQAWHIPVLEAEEKPAKVSPP 889

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..388	CDD:107377	73/406 (18%)
		ANF_receptor	39..371	CDD:279440	71/389 (18%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	115/415 (28%)
		Lig_chan	533..807	CDD:278489	88/314 (28%)
Ir8a	NP_727328.1	PBP2_iGluR_putative	383..786	CDD:270435	118/424 (28%)
		Lig_chan	520..818	CDD:278489	88/314 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	82	0.746	Domainoid score	I2907
eggNOG	1	0.900	-	-		E1_KOG1052
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	1	1.000	-	-		mtm1027
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR18966
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.910