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Protein Alignment Ekar and Gria2

DIOPT Version :9

Sequence 1:	NP_001036250.1	Gene:	Ekar / 43806	FlyBaseID:	FBgn0039916	Length:	899	Species:	Drosophila melanogaster
Sequence 2:	NP_001077280.1	Gene:	Gria2 / 29627	RGDID:	61862	Length:	883	Species:	Rattus norvegicus

Alignment Length:	876	Identity:	304/876 - (34%)
Similarity:	480/876 - (54%)	Gaps:	78/876 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 VRIGAIFSNQPGMYNSELAFRYAIHRLNMDKSLLPETTVDYYVEYVNRFDSFETVQKVCKLIRVG 87
            ::||.:|   |...:.|    |:..|:.|.:....|..:..:::.:...:||......|.....|
  Rat    27 IQIGGLF---PRGADQE----YSAFRVGMVQFSTSEFRLTPHIDNLEVANSFAVTNAFCSQFSRG 84

  Fly    88 VQAVFSPTDSVLATHINSICDALDIPNIGRS-----AHDFSINVYPSKQLVNYAFNDVIQYLNWT 147
            |.|:|...|......|.|.|..|.:..|..|     .|.|.|.:.|.   :..|...:|:|..|.
  Rat    85 VYAIFGFYDKKSVNTITSFCGTLHVSFITPSFPTDGTHPFVIQMRPD---LKGALLSLIEYYQWD 146

  Fly   148 RFGILHEKENGIINLHQLSRSFHGE------VHMRQVSRD----SYVSALNEFKGKEIHNIIIDT 202
            :|..|::.:.|:..|..:..|...:      :::..::.|    :|.|...:.:.|:...:|:|.
  Rat   147 KFAYLYDSDRGLSTLQAVLDSAAEKKWQVTAINVGNINNDKKDETYRSLFQDLELKKERRVILDC 211

  Fly   203 NSNGISILLKNILQQQMNEYKYHYLFTSFDLETYDLEDFKYNFVNITSFRLVDTADVGVKQILKD 267
            ..:.::.::..::....:...|||:..:......||...::...|::.|::||..|..|.:.::.
  Rat   212 ERDKVNDIVDQVITIGKHVKGYHYIIANLGFTDGDLLKIQFGGANVSGFQIVDYDDSLVSKFIER 276

  Fly   268 IGLYSHHIFKKPYLNLHIKKSTILESEPALMFDSVYVFAIGLQTLEQSHSLTLLNIS-------C 325
            ...    :.:|.|...|   :..::...||.:|:|.|.....:.|.:..    :.||       |
  Rat   277 WST----LEEKEYPGAH---TATIKYTSALTYDAVQVMTEAFRNLRKQR----IEISRRGNAGDC 330

  Fly   326 EEENS--WDGGLSLINYLNAVEWKGLTGPIQF-KDGQRVQFKLDLIKLKQHSIVKVGEWTPHGHL 387
            ....:  |..|:.:...|..|:.:||:|.|:| ::|:|:.:.:::::||.:...|:|.|:....:
  Rat   331 LANPAVPWGQGVEIERALKQVQVEGLSGNIKFDQNGKRINYTINIMELKTNGPRKIGYWSEVDKM 395

  Fly   388 --NITE-PSMFFDAGSMNVTLVVITILETPYVMMHYGKN---FTGNERFYGFCVDILETISREVG 446
              .:|| ||....:|..|.|:||.||||:|||||.  ||   ..||||:.|:|||:...|::..|
  Rat   396 VVTLTELPSGNDTSGLENKTVVVTTILESPYVMMK--KNHEMLEGNERYEGYCVDLAAEIAKHCG 458

  Fly   447 FDYILDLVPDRKYGAKDPETGEWNGMVAQLMKYKADLAVGSMTITYARESVIDFTKPFMNLGISI 511
            |.|.|.:|.|.||||:|.:|..|||||.:|:..|||:|:..:|||..||.||||:||||:|||||
  Rat   459 FKYKLTIVGDGKYGARDADTKIWNGMVGELVYGKADIAIAPLTITLVREEVIDFSKPFMSLGISI 523

  Fly   512 LFKVPTSEPTRLFSFMNPLAIEIWIYVLIAYFLVSLCIYIVGKLSPIEW---KCINACDLENISI 573
            :.|.|......:|||::|||.|||:.::.||..||:.:::|.:.||.||   :..:..:.::...
  Rat   524 MIKKPQKSKPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHTEEFEDGRETQSSES 588

  Fly   574 GNQFSLTDSFWFTIGTFMQQSPDIYPRAMSTRIISSTWGFFSLIIVASYTANLAAFLTTERMINP 638
            .|:|.:.:|.||::|.||:|..||.||::|.||:...|.||:|||::|||||||||||.|||::|
  Rat   589 TNEFGIFNSLWFSLGAFMRQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSP 653

  Fly   639 IENAEDLASQTEISYGTLDSGSTMTFFRDSVIETYKKIWRSMDNKKPSAFTTTYEDGIKRV--NQ 701
            ||:||||:.||||:|||||||||..|||.|.|..:.|:|..|.:.:||.|..|..:|:.||  ::
  Rat   654 IESAEDLSKQTEIAYGTLDSGSTKEFFRRSKIAVFDKMWTYMRSAEPSVFVRTTAEGVARVRKSK 718

  Fly   702 GNYAFLMESTMLDYIVQR-DCNLTQIGGLLDTKGYGIATPKGSPWRDKISLAILELQERGDIQML 765
            |.||:|:||||.:||.|| .|:..::||.||:|||||||||||...:.::||:|:|.|:|.:..|
  Rat   719 GKYAYLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGIATPKGSSLGNAVNLAVLKLNEQGLLDKL 783

  Fly   766 YDKWWKNTDETCTRKNTSKQSKANSLGLESIGGVFVVLIAGIIVAAVVAFFEFWYNFR------- 823
            .:|||.:..| |.......:.|.::|.|.::.|||.:|:.|:.:|.:||..||.|..|
  Rat   784 KNKWWYDKGE-CGSGGGDSKEKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMK 847

  Fly   824 -----YNYEATPSQSVVN-----NKYNQDGI 844
                 .|...:.||:..|     ..||..||
  Rat   848 VAKNPQNINPSSSQNSQNFATYKEGYNVYGI 878

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.