DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ekar and T25E4.2

DIOPT Version :9

Sequence 1:	NP_001036250.1	Gene:	Ekar / 43806	FlyBaseID:	FBgn0039916	Length:	899	Species:	Drosophila melanogaster
Sequence 2:	NP_001364710.1	Gene:	T25E4.2 / 188897	WormBaseID:	WBGene00020804	Length:	455	Species:	Caenorhabditis elegans

Alignment Length:	236	Identity:	57/236 - (24%)
Similarity:	84/236 - (35%)	Gaps:	59/236 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   443 REVGFDYILDLVPDRKY--GAKDPETG---EWNGMVAQLMKY---------------------KA 481
            |.||:...:..|....|  ....|:.|   |:..|..|||..                     .|
Worm     9 RAVGYQTDVPYVSLSNYCWSFNCPKPGAEVEFLNMTFQLMNSTATIVQIDADIEQSIDMVSNGSA 73

  Fly   482 DLAVGSMTITYARESVIDFTKP--FMNLGISILFKVP----TSEPTRLFSFMNPLAIEIWIYVLI 540
            |:.:.|...|..|...:|||.|  |:..|. ::.::|    .....|||.: :.|||.| .:.||
Worm    74 DITLVSARQTLDRMKKVDFTTPIGFVYYGY-LVREIPELAVADYIMRLFDY-DTLAILI-SFGLI 135

  Fly   541 AYFLVSLCIYIVG--KLSPIEWKCINACDLENISIGNQFSLTDSFWFTIGTFMQQSPDIYPRAMS 603
            ...|:.|..:|.|  ..|.::|..| :|.          .:...|.|.|     .||      :.
Worm   136 IGALLYLYTWIFGLRVRSLLDWMFI-SCS----------GIIHQFMFRI-----SSP------IC 178

  Fly   604 TRIISSTWGFFSLIIVASYTANLAAFLTTERMINPIENAED 644
            ..::...|....|:|:..|.|.|.:||........|.|..|
Worm   179 ALVLIGFWLLCCLVIITYYEAKLKSFLLLSHHRGTIFNTLD 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..388	CDD:107377
		ANF_receptor	39..371	CDD:279440
		PBP2_iGluR_Kainate	402..771	CDD:270432	57/236 (24%)
		Lig_chan	533..807	CDD:278489	27/114 (24%)
T25E4.2	NP_001364710.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1052
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900