Protein Alignment Ekar and grid1

DIOPT Version :9

• Sequence 1: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: NP_001096470.1
• Gene: grid1 / 100125089
• XenbaseID: XB-GENE-990290
• Length: 1009
• Species: Xenopus tropicalis
• Alignment Length: 905
• Identity: 241/905 - (26%)
• Similarity: 437/905 - (48%)
• Gaps: 111/905 - (12%)

  Fly     9 LFQFLSYGLGVPPLVRIGAIFSNQPGMYNSELAFRYAIHRLNMDKSLLPETTVDYYVEYVNRFDS 73
            :||.||  :....::.|||||  :......:..|:.|:..|:::..:|....:.|.::::...:.
 Frog    12 IFQCLS--VRADSIIHIGAIF--EENAVKDDEVFQLAVSDLSLNDDILQSEKITYSIKFIEANNP 72

  Fly    74 FETVQKVCKLIRVGVQAVFSPTDSVLATHINSICDALDIPNI---------GRSAHDFSINVYPS 129
            |:.||:.|.|:..|:.|:.:.|....|..:.|:.||:.||:|         .|:...|:    ||
 Frog    73 FQAVQEACDLMTQGILALVTSTGCASANALQSLTDAMHIPHIFVQRNSGGSPRTVCQFN----PS 133

  Fly   130 KQLVNYA--------FNDV----IQYLNWTRFGILHEKENGIINLH----QLSRSFHGEVHMRQV 178
            .:...|.        .|||    :..|.|.:|.:.::.:..|..|.    |.|| ...:|.:::|
 Frog   134 PEGEEYTLAARPPVRLNDVMLKLVTELRWQKFIVFYDSDYDIRGLQGFLDQASR-LGLDVSLQKV 197

  Fly   179 SRD---SYVSALNEFKGKEIH-------NIIIDTNSNGISILLKNILQQQMNEYKYHYLFTSFDL 233
            .|:   .:.:.....|.:|::       ..|:..:..|....:...::..:.....|:::.:.::
 Frog   198 DRNISRVFATLFTSMKTEELNRYRDTLRRAILLLSPRGAQSFISEAVETNLASKDSHWVYVNEEI 262

  Fly   234 ETYDLEDFKYNFV-NITSFRLVDTADVGVKQILKDIGL----YSHHIFKKP------YLNLHIKK 287
            ...::.:..::.: .||..|.:..:       |||..:    .:|.|...|      ||.:
 Frog   263 NDAEIVELVHSALGRITVIRQIFPS-------LKDNNIRCVRNNHRIASLPCDPQEGYLQM---- 316

  Fly   288 STILESEPALMFDSVYVFAIGL-QTLEQS--HSLTLLNISCEEENSWDGGLSLINYLNAVEWKGL 349
               |:.....::|||.:.|... :.||..  ||:..||...:....|:||.|:::.:......||
 Frog   317 ---LQVSNLYLYDSVLMLANAFHRKLEDRKWHSMASLNCMRKSTKPWNGGRSMLDTIKKGRITGL 378

  Fly   350 TGPIQFKD---GQRVQFKL---DLIKLKQHSIVKVGEWTPHGHLNITEPSMFFDAGSMNVTLVVI 408
            ||.::||:   ...|||::   ...:.....:.::..|......|.:......:.....:||.|:
 Frog   379 TGIMEFKEAGANPHVQFEILGTSYSETFGKDVRRLATWDSMKGFNGSLQEKPLNNDLQGLTLKVV 443

  Fly   409 TILETPYVMMHYGKNFTGN-ERFYGFCVDILETISREVGFDYILDLVPDRKYGAKDPETGEWNGM 472
            |:||.|:||:  .:|..|. :|:.||.::||:.:|..:||.|.:...||.||| .....|.||||
 Frog   444 TVLEEPFVMV--AENILGQPKRYKGFSIEILDELSNRLGFKYEIYQAPDGKYG-HQLSNGSWNGM 505

  Fly   473 VAQLMKYKADLAVGSMTITYARESVIDFTKPFMNLGISILFKVPTSEPTRLFSFMNPLAIEIWIY 537
            :.:|:..:||:|:.::|||..||:|:||||.:::..:.||.|.| .|...:||...|....:|..
 Frog   506 IGELINKRADIAISAITITPERENVVDFTKRYLDYSVGILIKKP-EERINIFSLFAPFDFAVWAC 569

  Fly   538 VLIAYFLVSLCIYIVGKLSPIEWKCINACDLENISIGNQFSLTDSFWFTIGTFMQQSPDIYPRAM 602
            :.....:|.:.|:::.::     :.:.|.:....|.....:|..:.|...|.|:||..:....::
 Frog   570 IAAVIPVVGVLIFVLNRI-----QAVRAQNSSQTSQSTSSTLHSAIWIVYGAFVQQGGESAANSV 629

  Fly   603 STRIISSTWGFFSLIIVASYTANLAAFLTTERMINPIENAEDLASQTEISYGTLDSGSTMTFFR- 666
            :.||:..:|..|:||:.:|||||||||||..||.|||...:|||.|.::.|||:...|...:|:
 Frog   630 AMRIVMGSWWLFTLIVCSSYTANLAAFLTVSRMDNPIRTFQDLAKQVDLPYGTVKDSSVYEYFKS 694

  Fly   667 ---DSVIE--TYKKIWRSM-DNKKPSAFTTTYEDGIKRVNQGNYAFLMESTMLDY--IVQRDCNL 723
               :::::  |:.::||:: .|.......::..:||::..:||||||.:.|:::|  :...:|::
 Frog   695 KGTNTLVQDRTFAELWRTIGKNNGSDNCVSSPSEGIRKAKRGNYAFLWDVTVVEYAALTDDECSV 759

  Fly   724 TQIGGLLDTKGYGIATPKGSPWRDKISLAILELQERGDIQMLYDKWWKNTDETCTRKNTSKQSKA 788
            ...|..:.:||||||...|||:||..|..|||.|:.|.:.:|.:|||..|.......:.:.|:..
 Frog   760 AVTGNTISSKGYGIALQHGSPYRDIFSQRILEFQDSGRLDVLKEKWWPRTGRCDLNSHNNAQNDG 824

  Fly   789 NSLGLESIGGVFVVLIAGIIVAAVVAFFEFWYNFRYNYEATPSQSVVNNKYNQDGILESE 848
            .:|.|.|..|||.:|..|:::|.:||..|.|:|              :|:..||...|.:
 Frog   825 KALKLHSFAGVFCILAIGLLLACLVAALELWWN--------------SNRCRQDSPKEDK 870

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..388	CDD:107377	85/418 (20%)
		ANF_receptor	39..371	CDD:279440	79/386 (20%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	130/378 (34%)
		Lig_chan	533..807	CDD:278489	88/282 (31%)
grid1	NP_001096470.1	PBP1_iGluR_delta_1	25..424	CDD:107387	85/419 (20%)
		ANF_receptor	39..400	CDD:279440	79/379 (21%)
		PBP2_iGluR_delta_1	437..807	CDD:270448	130/378 (34%)
		Lig_chan	565..842	CDD:278489	88/281 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18966
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.100