Protein Alignment Ekar and gria4

DIOPT Version :9

• Sequence 1: NP_001036250.1
• Gene: Ekar / 43806
• FlyBaseID: FBgn0039916
• Length: 899
• Species: Drosophila melanogaster
• Sequence 2: XP_031751480.1
• Gene: gria4 / 100125052
• XenbaseID: XB-GENE-5838893
• Length: 902
• Species: Xenopus tropicalis
• Alignment Length: 940
• Identity: 329/940 - (35%)
• Similarity: 495/940 - (52%)
• Gaps: 126/940 - (13%)

  Fly     1 MLIASGFLLFQFLSYGLGV---PPLVRIGAIF-SNQPGMYNSELAFRYAI--HRLNMDKS----- 54
            :|..|||       :||.:   |..|:||.:| .|....|.   |||.||  |..:.::|
 Frog     9 VLFFSGF-------WGLAMGAFPSSVQIGGLFIRNTDQEYT---AFRLAIFLHNTSPNESEALFN 63

  Fly    55 LLPETTVDYYVEYVNRFDSFETVQKVCKLIRVGVQAVFSPTDSVLATHINSICDALDI------- 112
            |:|      :|:.:...:||......|.....||.|:|...|......:.|.|.||.|
 Frog    64 LVP------HVDNIETSNSFAVTNAFCSQYSRGVFAIFGLYDKRSVHTLTSFCSALHISLITPSF 122

  Fly   113 PNIGRSAHDFSINVYPSKQLVNYAFNDVIQYLNWTRFGILHEKENGIINLHQLSRSFHGE----- 172
            |..|.|  .|.:.:.||   :..|...::.:..|..:..|::.:.|...|..:... .|:
 Frog   123 PTEGES--QFVLQLRPS---LRGALLSLLDHYGWNHYVFLYDTDRGYSILQAIMEK-AGQNGWQV 181

  Fly   173 --VHMRQVSRDSYVSALNEFKGKEIHNIIIDTNSNGISILLKNILQQQMNEYK----YHYLFTSF 231
              :.:...:..||...|.:...::.:..:||....    .|:|||:|.::..|    |||:..:.
 Frog   182 SAICVENFNDASYRRLLEDLDRRQENKFVIDCEVE----RLQNILEQIVSVGKHVKGYHYIIANL 242

  Fly   232 DLETYDLEDFKYNFVNITSFRLVDTADVGVKQILKDIGLYSHHIFKKPYLNLHIKKSTIL----- 291
            ..:...|:.|.:...|:|.|:|||                    |..|.:...:::...|
 Frog   243 GFKDISLDRFMHGGANVTGFQLVD--------------------FNTPIVTELMQRWKTLDQREY 287

  Fly   292 ---ESEP----ALMFDSVYVFAIGLQTLEQSHSLTLLNIS---------CEEENSWDGGLSLINY 340
               ||.|    ||.:|.|.|.|...:.|.:..    :::|         ......|..|:.:...
 Frog   288 PGSESPPKYTSALTYDGVLVMAEAFRILRRQK----IDLSRRGNAGDCLANPAAPWGQGIDMERT 348

  Fly   341 LNAVEWKGLTGPIQFKD-GQRVQFKLDLIKLKQHSIVKVGEWTPHGHLNIT--EPSMFFD-AGSM 401
            |..|..:||||.|||.. |:||.:.:|:::||.:.:.|:|.|.....|.:.  ||:...| :|..
 Frog   349 LKQVRIQGLTGNIQFDHYGRRVNYTMDVLELKSNGLRKIGYWNDMDKLVLLQHEPAFKNDSSGIE 413

  Fly   402 NVTLVVITILETPYVMMHYGKN---FTGNERFYGFCVDILETISREVGFDYILDLVPDRKYGAKD 463
            |.|::|.||||.||||  |.||   ..||::|.|:|||:...|::.:|..|.:.:|||.||||:|
 Frog   414 NRTVIVTTILEAPYVM--YKKNHELLEGNDKFEGYCVDLAYEIAKHIGIKYKIAIVPDGKYGARD 476

  Fly   464 PETGEWNGMVAQLMKYKADLAVGSMTITYARESVIDFTKPFMNLGISILFKVPTSEPTRLFSFMN 528
            .||..|||||.:|:..||::||..:|||..||.||||:||||:|||||:.|.|......:|||::
 Frog   477 SETKIWNGMVGELVYGKAEIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLD 541

  Fly   529 PLAIEIWIYVLIAYFLVSLCIYIVGKLSPIEWKCINACDLENISIG------NQFSLTDSFWFTI 587
            |||.|||:.::.||..||:.:::|.:.||.||   :..:.|:...|      |:|.:.:|.||::
 Frog   542 PLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEW---HTEEPEDGKEGPSDQPPNEFGIFNSLWFSL 603

  Fly   588 GTFMQQSPDIYPRAMSTRIISSTWGFFSLIIVASYTANLAAFLTTERMINPIENAEDLASQTEIS 652
            |.||||..||.||::|.||:...|.||:|||::|||||||||||.|||::|||:|||||.||||:
 Frog   604 GAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVERMVSPIESAEDLAKQTEIA 668

  Fly   653 YGTLDSGSTMTFFRDSVIETYKKIWRSMDNKKPSAFTTTYEDGIKRV--NQGNYAFLMESTMLDY 715
            |||||:|||..||:.|.|..|:|:|..|.:.:||.||.|..:|:.||  ::|.:|||:||||.:|
 Frog   669 YGTLDAGSTKEFFKRSKIAVYEKMWTYMKSAEPSVFTKTTAEGVARVRKSKGKFAFLLESTMNEY 733

  Fly   716 IVQR-DCNLTQIGGLLDTKGYGIATPKGSPWRDKISLAILELQERGDIQMLYDKWWKNTDETCTR 779
            |.|| .|:..::||.||:||||:||||.|..|:.::||:|:|.|:|.:..|.:|||.:..| |..
 Frog   734 IEQRKPCDTMKVGGNLDSKGYGVATPKHSQLRNAVNLAVLKLNEQGLLDKLKNKWWYDKGE-CGS 797

  Fly   780 KNTSKQSKANSLGLESIGGVFVVLIAGIIVAAVVAFFEFWYNFR---YNYEATPSQSVVNN-KYN 840
            .....:.|.::|.|.::.|||.:|:.|:.:|.:||..||.|..|   ...:.|.|:::.|. :.:
 Frog   798 GGGDSKDKTSALSLSNVAGVFYILVGGLGLAMLVALIEFCYKSRAEAKRMKLTFSEAIRNKARLS 862

  Fly   841 QDGILESERNYTPPDRSFWIEIAEELRYAS 870
            ..|.:........||....:.....||.:|
 Frog   863 ITGSIGENGRVLTPDCPKAVHTGTALRQSS 892

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ekar	NP_001036250.1	PBP1_iGluR_Kainate	24..388	CDD:107377	96/411 (23%)
		ANF_receptor	39..371	CDD:279440	86/378 (23%)
		PBP2_iGluR_Kainate	402..771	CDD:270432	193/380 (51%)
		Lig_chan	533..807	CDD:278489	133/282 (47%)
gria4	XP_031751480.1	PBP1_iGluR_AMPA_GluR4	28..400	CDD:380611	97/414 (23%)
		PBP2_iGluR_AMPA_GluR4	414..795	CDD:270445	195/386 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000021
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000