Protein Alignment Gat and Slc6a21

DIOPT Version :9

• Sequence 1: NP_651930.2
• Gene: Gat / 43805
• FlyBaseID: FBgn0039915
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_006541333.1
• Gene: Slc6a21 / 76713
• MGIID: 1923963
• Length: 749
• Species: Mus musculus
• Alignment Length: 700
• Identity: 178/700 - (25%)
• Similarity: 306/700 - (43%)
• Gaps: 128/700 - (18%)

  Fly    29 HTTSLQSSSPTTTDTSNKQQLVKIEQLPDRGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNGG 93
            ||.|.:|.:||:.....:.:.|::.::|:... :.|.:.||.:|..:||||:.|||||||::|||
Mouse    20 HTASKKSDNPTSVSRGFRTREVRVTKIPNHFQ-AKKTENILILVAFSIGLGSTWRFPYLCHQNGG 83

  Fly    94 GAFILPYIITLFLAGIPMFFMELALGQMLTIGGLGVFK-IAPIFKGIGYAAAVMSCWMNVYY-IV 156
            |:|:|.|.|.|.|.|||:.:||:.:||.|.:..:..:| :.|...|:|| :.:::|.:.|.| ..
Mouse    84 GSFLLMYFILLLLLGIPLMYMEMVIGQWLRMDNIQAWKYLVPWLSGVGY-SNILACVLVVLYNSA 147

  Fly   157 ILAWAVFYFFMSMRADVPWRTCNNWWNTVNCVSQYERKNLHCWDKIINGTTQKVCSVSALNITSL 221
            :::|::||...|....:||:.|....|.                .::.|.|   |..|
Mouse   148 LVSWSLFYLGQSFDYPLPWQNCPLVENL----------------SMVAGNT---CLWS------- 186

  Fly   222 ELTDPVKEFWERRALQISHGIEE-IGNIRWELAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFP 285
               :|.:.||....||.|:.:|| |..:...:...|...||..|..:...:|.:..::.|:.||.
Mouse   187 ---EPHQYFWYHTLLQASNQMEEGIEVLVLNVTLCLFATWIFLYVTMVTRIKISVLMMIFSILFS 248

  Fly   286 YVLLTILLVRGITLPGALEGIKFYIIP-NFSKLTNSEVWIDAVTQIFFSYGLGLGTLVALGSYNK 349
            .|||....:|.:.|.|::....:.::. ..|.|::.:.|..|...:.:|.|||:||::...:|..
Mouse   249 NVLLLCFFIRTLFLNGSVRASLWRLVTIELSILSSLDAWRQAGGHVLYSLGLGMGTIITFSTYQP 313

  Fly   350 FTNNVYKDALIVCTVNSSTSMFAGFVIFSVIGF-------------------------------- 382
            ...|..|.|..|..||.:||:.:.||||.|:||
Mouse   314 RGENYIKWASFVAMVNLATSLLSSFVIFLVMGFWTTTSGTMCIKRSVSNLINLIANGVLPKAAWP 378

  Fly   383 ---MAHE----------------------QQRPVA-----DVAASGPGLAFLVYPSAVLQLPGSP 417
               :.|:                      |..|.:     :....||||:::.:..|:...|||.
Mouse   379 PGDIIHKPPLEYLAWINQLPNNLKSQVIHQTLPCSILIQKEKIMEGPGLSYVAFSQAISLFPGSS 443

  Fly   418 MWSCLFFFMLLLIGLDSQFCTMEGFITAIIDEWPQLLRKRKEIFIAIVCALSYLVGLTCITQGGM 482
            .|:.:||..|.::||.:....:||.:.. :.:......|...:...:||...:|..|...::.|.
Mouse   444 FWAIIFFMSLAIMGLGTMLTLLEGIVLP-LQKSISTFAKHPNLVQVLVCLGGFLGSLVFSSRPGS 507

  Fly   483 YIFQILDSYAVSGFCLLWLIFFECVSISWCYGVDRFYDGIKDMIGYYPTVW--WKFCWC-VTTPA 544
            |:..:.|...|. ..|:.::..:.:|::|.||:.||...:...:|  ..||  :.|.|. ||.|.
Mouse   508 YVVFLFDDLLVP-MVLIIIVVIQNLSLAWLYGIKRFRAEVFGQLG--SLVWSPFTFLWSYVTLPT 569

  Fly   545 --ICLGVFFFNI--------VQWTPVKYLDYSYPWWAHAFGWFTALSSMLYIPLYMF----WLWK 595
              :.|.::|.|:        |.|......:...|:.....||.|.||.:..:|:.::    |.:.
Mouse   570 LLVLLTIYFLNLYYSGSPYYVSWNDSMSHEVKQPYKKIPLGWVTFLSVLALLPILVYPLQHWWYL 634

  Fly   596 RTPG--ELSEK---IRALVRIDEDVTR-----LREKMLREAYAKEIEFNS 635
            ..|.  |..||   .:..|.:...||:     :|:..||.....:..|.|
Mouse   635 DDPNICETLEKPLSSKKTVTVPNRVTQWPVHPMRKLTLRNQEKSKALFQS 684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	163/640 (25%)
Slc6a21	XP_006541333.1	SLC5-6-like_sbd	48..622	CDD:382020	156/608 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920