Protein Alignment Gat and Slc6a17

DIOPT Version :9

• Sequence 1: NP_651930.2
• Gene: Gat / 43805
• FlyBaseID: FBgn0039915
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_001028251.1
• Gene: Slc6a17 / 613226
• RGDID: 1587185
• Length: 727
• Species: Rattus norvegicus
• Alignment Length: 674
• Identity: 219/674 - (32%)
• Similarity: 328/674 - (48%)
• Gaps: 126/674 - (18%)

  Fly    34 QSSSPTTTDTSNKQQLVKIE-QLPDRGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFI 97
            ||......:|..||::.:.| ...||.:|:||:.:||:.:|.::||||:|||||||.||||||::
  Rat    35 QSVLNVAGETGGKQKVAEEELDAEDRPAWNSKLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYL 99

  Fly    98 LPYIITLFLAGIPMFFMELALGQMLTIGGLGVFK-IAPIFKGIGYAAAVMSCWMNVYYIVILAWA 161
            :||::.|.:.|||:||:|||:||.:..|.:||:. :.|...|||:::.::..::.:||.||:.|:
  Rat   100 VPYLVLLIIIGIPLFFLELAVGQRIRRGSIGVWHYVCPRLGGIGFSSCIVCLFVGLYYNVIIGWS 164

  Fly   162 VFYFFMSMRADVPWRTCNNWWNTVNCVSQYERKNLHCWDKIINGTTQKV---CSVSALNITSLEL 223
            |||||.|.:..:||..|                     ..|.|||...|   |          |.
  Rat   165 VFYFFKSFQYPLPWSEC---------------------PVIRNGTVAVVEPEC----------EK 198

  Fly   224 TDPVKEFWERRALQISHGIEEIGNIRWELAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFPYVL 288
            :.....||.|.||.||:.|.|.|.:.|::...||:.|.:....:.||::.:|||:||::|||||:
  Rat   199 SSATTYFWYREALDISNSISESGGLNWKMTVCLLVAWSIVGMAVVKGIQSSGKVMYFSSLFPYVV 263

  Fly   289 LTILLVRGITLPGALEGIKFYIIPNFSKLTNSEVWIDAVTQIFFSYGLGLGTLVALGSYNKFTNN 353
            |...||||:.|.||::||.....|...|:.:.:||.:|.||:||:.|||.|.::|..||||..||
  Rat   264 LACFLVRGLLLRGAVDGILHMFTPKLDKMLDPQVWREAATQVFFALGLGFGGVIAFSSYNKQDNN 328

  Fly   354 VYKDALIVCTVNSSTSMFAGFVIFSVIGFMAH--------------------------------- 385
            .:.||.:|..:|..||:.|..|:|:|:||.|:
  Rat   329 CHFDAALVSFINFFTSVLATLVVFAVLGFKANIMNEKCVVENAEKILGYLNSNVLSRDLIPPHVN 393

  Fly   386 --------------------EQQ-----------RPVADVAASGPGLAFLVYPSAVLQLPGSPMW 419
                                |:|           ....|.:..|.||||:.:..|:...|.||.|
  Rat   394 FSHLTTKDYSEMYNVIMTVKEKQFSALGLDPCLLEDELDKSVQGTGLAFIAFTEAMTHFPASPFW 458

  Fly   420 SCLFFFMLLLIGLDSQFCTMEGFITAIIDEWPQLLRKRKEIFIAIVCALSYLVGLTCITQGGMYI 484
            |.:||.||:.:||.|...||.|..|.|||.:    :..||:|....|..::.|||..:.:.|.|.
  Rat   459 SVMFFLMLINLGLGSMIGTMAGITTPIIDTF----KVPKEMFTVGCCVFAFFVGLLFVQRSGNYF 519

  Fly   485 FQILDSYAVSGFCLLWLIFFECVSISWCYGVDRFYDGIKDMIGYYP----TVWWKF----CWCVT 541
            ..:.|.|:.: ..|..::..|.::::|.||..:|...:.:|:|:.|    ...|||    |..|.
  Rat   520 VTMFDDYSAT-LPLTVIVILENIAVAWIYGTKKFMQELTEMLGFRPYRFYFYMWKFVSPLCMAVL 583

  Fly   542 TPA--ICLGVFFFNIVQW----TPVKYLDYSYPWWAHAFGWFTALSSMLYIP----LYMFWLWKR 596
            |.|  |.|||.......|    ...:||  .:|.||.|........:.|.||    |..|.|...
  Rat   584 TTASIIQLGVSPPGYSAWIKEEAAERYL--YFPNWAMALLITLIAVATLPIPVVFILRHFHLLSD 646

  Fly   597 TPGELSEKIRALVRIDEDVTRLRE 620
            ....||...:. .|:.:|::.|.|
  Rat   647 GSNTLSVSYKK-GRMMKDISNLEE 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	208/638 (33%)
Slc6a17	NP_001028251.1	SLC6sbd_NTT4	60..648	CDD:271403	206/625 (33%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	680..727

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820