Protein Alignment Gat and slc6a16b

DIOPT Version :10

• Sequence 1: NP_651930.2
• Gene: Gat / 43805
• FlyBaseID: FBgn0039915
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_001103944.1
• Gene: slc6a16b / 567809
• ZFINID: ZDB-GENE-070424-95
• Length: 676
• Species: Danio rerio
• Alignment Length: 640
• Identity: 211/640 - (32%)
• Similarity: 320/640 - (50%)
• Gaps: 113/640 - (17%)

  Fly    58 RGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFILPYIITLFLAGIPMFFMELALGQML 122
            |..|.||:::.|:.||.::||||||||||||::||||||||.|::.:.|.|:|:||:|||.||.:
Zfish    33 RDGWDSKVEYFLAQVGFSVGLGNVWRFPYLCHQNGGGAFILLYVVLMALVGVPLFFLELAAGQSI 97

  Fly   123 TIGGLGVFK-IAPIFKGIGYAAAVMSCWMNVYYIVILAWAVFYFFMSMRADVPWRTCNNWWNTVN 186
            ..|.:||:: |:|...||||::.|:..::.:||.||:.|::||...|.:..:||..|....|
Zfish    98 RQGSIGVWRHISPKLVGIGYSSCVVCFFVALYYNVIIGWSIFYLGNSFQYPLPWEKCPTEGN--- 159

  Fly   187 CVSQYERKNLHCWDKIINGTTQKVCSVSALNITSLELTDPVKEFWERRALQISHGIEEIGNIRWE 251
                               :|.|.|:.|:          |...||.|:||.|:..|:|.|...:.
Zfish   160 -------------------STVKECAASS----------PTAYFWYRKALDITDSIDETGEFNFI 195

  Fly   252 LAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFPYVLLTILLVRGITLPGALEGIKFYIIPNFSK 316
            |.|.||..|::....::||:|.:|||:||:::||||:|...|:||:||.||.|||||...|....
Zfish   196 LTGCLLAAWVIVCLAMYKGIKSSGKVMYFSSVFPYVVLLCFLIRGVTLDGASEGIKFMFYPRLEI 260

  Fly   317 LTNSEVWIDAVTQIFFSYGLGLGTLVALGSYNKFTNNVYKDALIVCTVNSSTSMFAGFVIFSVIG 381
            ..:.:||..|.||:||:.|||.|:::|..|||...||.::||..|..||..||:.|..|:|:|:|
Zfish   261 WADVQVWRQAATQVFFALGLGFGSVIAYSSYNPRNNNCHRDAFTVSGVNFMTSVLATLVVFAVLG 325

  Fly   382 FMA--------HEQQRPVADVAASGP--------------------------------------- 399
            |.|        ....:.:..|.:|.|
Zfish   326 FRAKTIAAECVKRNLKALLKVTSSAPLPVLSINASDVESISLDEYANWYSTQGMELSISDYNITA 390

  Fly   400 --------------GLAFLVYPSAVLQLPGSPMWSCLFFFMLLLIGLDSQFCTMEGFITAIIDEW 450
                          ||||:.:..|:...||||.||.|||.|||.:||.:.|.||.|.:|.:.|.:
Zfish   391 CSLEDELRQGVEETGLAFIAFTEAMTLFPGSPFWSALFFLMLLNLGLSTMFGTMAGILTPLTDTF 455

  Fly   451 PQLLRKRKEIFIAIVCALSYLVGLTCITQGGMYIFQILDSYAVSGFCLLWLIFFECVSISWCYGV 515
             :.||..|.||....|.:.:::||....:.|.|...:.|.|:.: ..|:.::.|:.:|:||.||.
Zfish   456 -KTLRNHKLIFTICSCTVGFVIGLVFTQRCGNYFVTMFDDYSAT-LPLIIVVIFQTISVSWVYGA 518

  Fly   516 DRFYDGIKDMIGYYPTVWWKFCWCVTTPAICLGVFFFNIVQ----------WTPVKYL--DYSYP 568
            |||.:.:|.|:.....|.:|:.|....|...||:...::::          |...|..  |..||
Zfish   519 DRFLEDLKQMLNRPVPVIYKYLWKFVCPIAMLGLLGASLLKMILKRPEYSAWNREKASKEDLPYP 583

  Fly   569 WWAHAFGWFTALSSMLYIPL-YMFWL----WKRTPGELSEKIRALVRIDEDVTRL 618
            .||.|......:.:.|.:|: |:..|    ..::|.:...:.......|.|:|.|
Zfish   584 DWALAVLIILIIIASLPVPIGYIHSLLLERLGQSPADTEARYTPCATTDTDLTPL 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	207/631 (33%)
slc6a16b	NP_001103944.1	SLC6sbd-B0AT-like	33..607	CDD:271364	205/607 (34%)