Protein Alignment Gat and slc6a15

DIOPT Version :9

• Sequence 1: NP_651930.2
• Gene: Gat / 43805
• FlyBaseID: FBgn0039915
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_001232001.1
• Gene: slc6a15 / 565315
• ZFINID: ZDB-GENE-050420-93
• Length: 741
• Species: Danio rerio
• Alignment Length: 681
• Identity: 215/681 - (31%)
• Similarity: 336/681 - (49%)
• Gaps: 132/681 - (19%)

  Fly    19 ESIE--MSKELGHTTSLQSSSPTTTDT-SNKQQLV-------KIEQLPDRGSWSSKMDFILSVVG 73
            ||::  :|.|.....|.:.||....|. .|||:.|       :.|:..:|.:|.||:.:||:.||
Zfish    19 ESVKDLLSNEDSCDDSFKKSSLMVGDVPQNKQKDVEEGSEEEEEEEEEERPAWGSKLQYILAQVG 83

  Fly    74 LAIGLGNVWRFPYLCYKNGGGAFILPYIITLFLAGIPMFFMELALGQMLTIGGLGVFK-IAPIFK 137
            .::||||||||||||.||||||:::||:|.|.|.|||:||:|||:||.:..|.:||:. |:|...
Zfish    84 FSVGLGNVWRFPYLCQKNGGGAYLVPYLILLLLIGIPLFFLELAVGQRIRRGSIGVWNYISPHLG 148

  Fly   138 GIGYAAAVMSCWMNVYYIVILAWAVFYFFMSMRADVPWRTCNNWWNTVNCVSQYERKNLHCWDKI 202
            |||:|:.::..::.:||.||:.|::|||..|.:..:||..|....|..|...:.|
Zfish   149 GIGFASCLVCFFVALYYNVIIGWSLFYFSQSFQQPLPWHECPLVKNKTNTYIEPE---------- 203

  Fly   203 INGTTQKVCSVSALNITSLELTDPVKEFWERRALQISHGIEEIGNIRWELAGTLLLVWILCYFCI 267
                    |          |.:.....:|.|.||.||..|.|.|.:.|.:...||..|.:....:
Zfish   204 --------C----------EKSSATTYYWYRVALDISDSISEGGGLNWRMTLCLLAAWTMVCLAM 250

  Fly   268 WKGVKWTGKVVYFTALFPYVLLTILLVRGITLPGALEGIKFYIIPNFSKLTNSEVWIDAVTQIFF 332
            .||::.:|||:||::|||||:|...|.|...|.|:::||.....|....:...:||.:|.||:||
Zfish   251 IKGIQSSGKVMYFSSLFPYVVLICFLARAFLLKGSVDGIIHMFTPKLEIMLEPKVWREAATQVFF 315

  Fly   333 SYGLGLGTLVALGSYNKFTNNVYKDALIVCTVNSSTSMFAGFVIFSVIGFMAH------------ 385
            :.|||.|.::|..||||..||.:.||::|..:|..||:.|..|:|:|:||.|:
Zfish   316 ALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATLVVFAVLGFKANIMNAKCVEMNTK 380

  Fly   386 --------------------------EQQRPVADV-------------------------AASGP 399
                                      |..:.:.::                         |..|.
Zfish   381 KIIGFLGKEINPGLIPHHINFSQVSPEDYQQMTNIIQGVMENDYPRLGLDNCDIKEELNKAVQGT 445

  Fly   400 GLAFLVYPSAVLQLPGSPMWSCLFFFMLLLIGLDSQFCTMEGFITAIIDEWPQLLRKRKEIFIAI 464
            ||||:.:..|:...|.||.||.:||.||:.:||.|.|.|::|.:|.|:|.:    :.|||.....
Zfish   446 GLAFIAFTEAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIQGILTPIVDTF----KVRKEYLTVG 506

  Fly   465 VCALSYLVGLTCITQGGMYIFQILDSYAVSGFCLLWLIFFECVSISWCYGVDRFYDGIKDMIGYY 529
            .|.|::.:|||.:.:.|.|...:.|.|:.: ..||.::..|.::::|.||.|:|::.:|||:|:.
Zfish   507 CCVLAFFIGLTFVQRSGNYFVAMFDDYSAT-LPLLIVVLLENIAVAWVYGTDKFFEDLKDMLGFT 570

  Fly   530 PTVWWKFCWCVTTPAICLGVFFFNIVQ----------WTP--VKYLDYSYPWWAHAFGWFTALSS 582
            |..::.:.|...||.:.||:...:::|          |..  .|....|||.|..|......:::
Zfish   571 PYRYYYYMWKFVTPVLLLGLLAASVIQLGLAPPSYSAWNQQLAKEQSLSYPPWGLAVCISLVVTA 635

  Fly   583 MLYIPLYMFWLWKRTPGELSEKIRALVRIDE 613
            :|.:|:...             :|.|..|||
Zfish   636 ILPVPVVFI-------------LRCLNIIDE 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	199/628 (32%)
slc6a15	NP_001232001.1	SLC5-6-like_sbd	68..646	CDD:294310	197/623 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010