DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gat and si:ch211-132b12.6

DIOPT Version :9

Sequence 1:	NP_651930.2	Gene:	Gat / 43805	FlyBaseID:	FBgn0039915	Length:	636	Species:	Drosophila melanogaster
Sequence 2:	NP_001038523.1	Gene:	si:ch211-132b12.6 / 564583	ZFINID:	ZDB-GENE-050420-179	Length:	577	Species:	Danio rerio

Alignment Length:	552	Identity:	258/552 - (46%)
Similarity:	372/552 - (67%)	Gaps:	25/552 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 EQLPDRGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFILPYIITLFLAGIPMFFMELA 117
            |::.:||.|..|.:|:|:|.|..:|||||||||||||:||||.|::||::.:...|:|:|.:|.|
Zfish     6 EEIEERGFWGKKAEFLLAVAGNVVGLGNVWRFPYLCYRNGGGVFLIPYLVFVVTCGLPLFLLETA 70

  Fly   118 LGQMLTIGGLGVF-KIAPIFKGIGYAAAVMSCWMNVYYIVILAWAVFYFFMSMRADVPWRTCNNW 181
            :||....||:..: ::.|:.:|:|||..:...:..:||.:|||||:||...|..:.:||.:|||.
Zfish    71 MGQFTHEGGITCWHRLCPLAQGVGYAGQLTVLYSCMYYTIILAWALFYLVSSFSSQLPWVSCNNI 135

  Fly   182 WNTVNCVSQYERKNLHCWDKIINGTTQKVCSVSALNITSLELTDPVKEFWERRALQISHGIEEIG 246
            |||.|||      ||...:...|.||       ..|.||     ...||||||.|.:|.|||:||
Zfish   136 WNTDNCV------NLAAGNLTFNRTT-------LANSTS-----AATEFWERRVLSLSGGIEDIG 182

  Fly   247 NIRWELAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFPYVLLTILLVRGITLPGALEGIKFYII 311
            .|.||:...|:.:||:||||||||||.|||||||||.||||:|.:||:||:||||||:|:.||:.
Zfish   183 KINWEILLCLIAMWIICYFCIWKGVKSTGKVVYFTATFPYVMLLVLLIRGLTLPGALQGVVFYLY 247

  Fly   312 PNFSKLTNSEVWIDAVTQIFFSYGLGLGTLVALGSYNKFTNNVYKDALIVCTVNSSTSMFAGFVI 376
            |..::|.:.:||::|.||:||||.:..|.|::|||||:::||.|:|:..:|.:||.||..|||.:
Zfish   248 PEPARLADPQVWMEAGTQVFFSYSVCSGILISLGSYNQYSNNCYRDSFWLCLLNSGTSFVAGFAV 312

  Fly   377 FSVIGFMAHEQQRPVADVAASGPGLAFLVYPSAVLQLPGSPMWSCLFFFMLLLIGLDSQFCTMEG 441
            |||:|||||.|..||.:||.|||||||:.||.|:..:|...:|:..||.|::|:||||||..:|.
Zfish   313 FSVLGFMAHVQGVPVEEVAESGPGLAFIAYPQAMAMMPFPQLWAVCFFIMIILLGLDSQFVGIEC 377

  Fly   442 FITAIIDEWPQLLRK--RKEIFIAIVCALSYLVGLTCITQGGMYIFQILDSYAVSGFCLLWLIFF 504
            .||:::|.:|::||:  |:|:|:.::|...:...|..:|:||||:||:.|:||.:|.|||:|..|
Zfish   378 VITSVMDLFPEVLRRAGRRELFVLLLCLTCFFGQLIMVTEGGMYVFQLFDNYACNGACLLFLSVF 442

  Fly   505 ECVSISWCYGVDRFYDGIKDMIGYYPTVWWKFCWCVTTPAICLGVFFFNIVQWTPVKYLD-YSYP 568
            |.::|.|.:|.::.:|.|:||....|..|:..||...||.:.|..|.:::|::||:.:.. |.||
Zfish   443 ESLAIGWLFGAEKMFDIIEDMTESRPNYWFMLCWKYLTPLVSLMSFVYSMVRYTPLTFNRWYVYP 507

  Fly   569 WWAHAFGWFTALSSMLYIP---LYMFWLWKRT 597
            .||:|.||..||||:|.:|   |...|..|.|
Zfish   508 DWAYALGWLLALSSILLVPGWALGQMWAGKGT 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	257/547 (47%)
si:ch211-132b12.6	NP_001038523.1	SLC6sbd-TauT-like	11..550	CDD:271387	257/547 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D145627at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100347
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.920