Protein Alignment Gat and slc6a7

DIOPT Version :10

• Sequence 1: NP_651930.2
• Gene: Gat / 43805
• FlyBaseID: FBgn0039915
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_001074049.1
• Gene: slc6a7 / 562050
• ZFINID: ZDB-GENE-070112-1492
• Length: 537
• Species: Danio rerio
• Alignment Length: 519
• Identity: 202/519 - (38%)
• Similarity: 301/519 - (57%)
• Gaps: 43/519 - (8%)

  Fly   104 LFLAGIPMFFMELALGQMLTIGGLGVFKIAPIFKGIGYAAAVMSCWMNVYYIVILAWAVFYFFMS 168
            ||..|:|:|.|||:|||....|.:.|:|..|:.||||.....:|..:.:||.||:||..:|...|
Zfish     2 LFFTGMPLFLMELSLGQYGAAGPITVWKCCPLLKGIGIGMLCVSTLVCLYYNVIIAWTFYYLGSS 66

  Fly   169 MRADVPWRTCNNWWNTVNCVSQYERKNLHCWDKIINGTTQKVCSVSALNITSLELTDPVKEFWER 233
            .::.:|| :|:...|...|.::             ..:||                .|.:.||..
Zfish    67 FQSPLPW-SCDALQNIALCANK-------------TNSTQ----------------SPSEVFWNE 101

  Fly   234 RALQISH--GIEEIGNIRWELAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFPYVLLTILLVRG 296
            :.|.:.|  |:.:.|.:||.||..||..||:.:.|:.||:..:|||||.||.|||.:|.:|::||
Zfish   102 KVLGVVHSTGLSDPGPVRWPLALCLLAAWIIIFLCMLKGIHSSGKVVYLTATFPYFVLLVLIIRG 166

  Fly   297 ITLPGALEGIKFYIIPNFSKLTNSEVWIDAVTQIFFSYGLGLGTLVALGSYNKFTNNVYKDALIV 361
            .||.|:|:|:.||:.|.:.:|.:::||.||.:|||:|.|:|:|.|:::.|||||.|||.:|.:|:
Zfish   167 ATLEGSLDGVAFYLTPKWDQLADAQVWNDAASQIFYSLGIGVGGLLSMASYNKFDNNVIRDTIII 231

  Fly   362 CTVNSSTSMFAGFVIFSVIGFMAHEQQRPVADVAASGPGLAFLVYPSAVLQLPGSPMWSCLFFFM 426
            ...|.|||.||||.|||::|.||.::..||..||.|||||||:.||.|:..||||..||.|||.|
Zfish   232 TIGNCSTSFFAGFAIFSILGHMAFKKGVPVDKVADSGPGLAFVAYPEALALLPGSVFWSILFFLM 296

  Fly   427 LLLIGLDSQFCTMEGFITAIIDEWPQLLR--KRKEIFIAIVCALSYLVGLTCITQGGMYIFQILD 489
            |.::|:|:.|..|||..||::||:|||..  |.|.:|:|::|...||:||..||.||:|.|.::|
Zfish   297 LFMLGVDTLFGNMEGICTAVLDEFPQLRSNLKHKTLFLAVLCFSFYLMGLLLITDGGIYWFTLID 361

  Fly   490 SYAVSGFCLLWLIFFECVSISWCYGVDRFYDGIKDMIGYYP------TVWWKFCWCVTTPAICLG 548
            |::.| |.|:.:..|.|:.||:.|||::|...|.|||...|      .:::|.||.|.||.:...
Zfish   362 SFSTS-FGLIIITLFMCIGISFFYGVNQFCQDIVDMICRCPPWCTKMLLYFKACWVVFTPFLLTF 425

  Fly   549 VFFFNIVQW--TPVKYLDYSYPWWAHAFGWFTALSSMLYIPLYMFWLWKRTPGELSEKIRALVR 610
            :..:..::.  |.::|..|.||.|..|.|........|.|.::......:..|.|.::.:..:|
Zfish   426 ILTYIFIEMYRTSLRYGSYVYPIWGKALGVCMGALCCLQILIWAIVAISKESGTLKDRFKKSIR 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	202/519 (39%)
slc6a7	NP_001074049.1	SLC5-6-like_sbd	1..495	CDD:444915	202/519 (39%)