Protein Alignment Gat and SerT

DIOPT Version :9

• Sequence 1: NP_651930.2
• Gene: Gat / 43805
• FlyBaseID: FBgn0039915
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_001369117.1
• Gene: SerT / 37895
• FlyBaseID: FBgn0010414
• Length: 768
• Species: Drosophila melanogaster
• Alignment Length: 593
• Identity: 249/593 - (41%)
• Similarity: 368/593 - (62%)
• Gaps: 47/593 - (7%)

  Fly     4 NSASDGDGGGDVCKHESIEMSKELGHTTSLQSSSPTTTDTSNKQQLVKIEQLP-DRGSWSSKMDF 67
            ::..|||                  |||..:.:.|.....:|.::::.:.... .|.:|..|.:|
  Fly    37 SNEDDGD------------------HTTPAKVTDPLAPKLANNERILVVSVTERTRETWGQKAEF 83

  Fly    68 ILSVVGLAIGLGNVWRFPYLCYKNGGGAFILPYIITLFLAGIPMFFMELALGQMLTIGGLGVFK- 131
            :|:|:|.|:.|||||||||:||:||||||::||.:.|...|:|:|:|||||||....|.|.::|
  Fly    84 LLAVIGFAVDLGNVWRFPYICYQNGGGAFLVPYCLFLIFGGLPLFYMELALGQFHRCGCLSIWKR 148

  Fly   132 IAPIFKGIGYAAAVMSCWMNVYYIVILAWAVFYFFMSMRADVPWRTCNNWWNTVNCVSQYERKNL 196
            |.|..||:|||..::..:|.:||..|:.|||:|.|.|..:.:||.:|:|.|||.||:
  Fly   149 ICPALKGVGYAICLIDIYMGMYYNTIIGWAVYYLFASFTSKLPWTSCDNPWNTENCM-------- 205

  Fly   197 HCWDKIINGTTQKVCSVSALNITSLELTDPVKEFWERRALQI--SHGIEEIGNIRWELAGTLLLV 259
                           .|::.|.|.| .|.|.|||:||:.|:.  .:|::.:|.::..||..:..|
  Fly   206 ---------------QVTSENFTEL-ATSPAKEFFERKVLESYKGNGLDFMGPVKPTLALCVFGV 254

  Fly   260 WILCYFCIWKGVKWTGKVVYFTALFPYVLLTILLVRGITLPGALEGIKFYIIPNFSKLTNSEVWI 324
            ::|.||.:||||:..||||:.|||.|||:|.||||||::||||.||||:|:.|.:.||.||:|||
  Fly   255 FVLVYFSLWKGVRSAGKVVWVTALAPYVVLIILLVRGVSLPGADEGIKYYLTPEWHKLKNSKVWI 319

  Fly   325 DAVTQIFFSYGLGLGTLVALGSYNKFTNNVYKDALIVCTVNSSTSMFAGFVIFSVIGFMAHEQQR 389
            ||.:|||||.|.|.|||:||.|||||.||.|:||||..::|..||..||||||||:|:||:.|:.
  Fly   320 DAASQIFFSLGPGFGTLLALSSYNKFNNNCYRDALITSSINCLTSFLAGFVIFSVLGYMAYVQKT 384

  Fly   390 PVADVAASGPGLAFLVYPSAVLQLPGSPMWSCLFFFMLLLIGLDSQFCTMEGFITAIIDEWPQLL 454
            .:..|...||||.|:|||.|:..:.||..||.:||.||:.:||||.|..:|..|||:.||:|:::
  Fly   385 SIDKVGLEGPGLVFIVYPEAIATMSGSVFWSIIFFLMLITLGLDSTFGGLEAMITALCDEYPRVI 449

  Fly   455 RKRKEIFIAIVCALSYLVGLTCITQGGMYIFQILDSYAVSGFCLLWLIFFECVSISWCYGVDRFY 519
            .:|:|:|:.::.|..:|..|..:|.||:.:...|:.|. .|..:|:::|.|...:.|.||||||.
  Fly   450 GRRRELFVLLLLAFIFLCALPTMTYGGVVLVNFLNVYG-PGLAILFVVFVEAAGVFWFYGVDRFS 513

  Fly   520 DGIKDMIGYYPTVWWKFCWCVTTPAICLGVFFFNIVQWTPVKYLDYSYPWWAHAFGWFTALSSML 584
            ..::.|:|..|.::|:.||...:|...|.:|.|:|:.:..:...:|.||.|::..||....||:|
  Fly   514 SDVEQMLGSKPGLFWRICWTYISPVFLLTIFIFSIMGYKEMLGEEYYYPDWSYQVGWAVTCSSVL 578

  Fly   585 YIPLYMFW 592
            .||:|:.:
  Fly   579 CIPMYIIY 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	241/538 (45%)
SerT	NP_001369117.1	SLC6sbd_SERT-like	74..607	CDD:271388	241/538 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440715
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850