DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gat and GlyT

DIOPT Version :9

Sequence 1:	NP_651930.2	Gene:	Gat / 43805	FlyBaseID:	FBgn0039915	Length:	636	Species:	Drosophila melanogaster
Sequence 2:	NP_611836.2	Gene:	GlyT / 37772	FlyBaseID:	FBgn0034911	Length:	1188	Species:	Drosophila melanogaster

Alignment Length:	618	Identity:	270/618 - (43%)
Similarity:	369/618 - (59%)	Gaps:	31/618 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 GDGGGDVCKHESIEMSKELGHTTSLQSSSPTTTDTSNKQQLVKIEQLPDRGSWSSKMDFILSVVG 73
            |.|||.||...:|...........|.::.|........:.        :||:|:.:.||:||::|
  Fly    16 GGGGGVVCPSTAISGCASGTALIQLDATGPGAGGAGESEH--------ERGTWTGRFDFLLSLLG 72

  Fly    74 LAIGLGNVWRFPYLCYKNGGGAFILPYIITLFLAGIPMFFMELALGQMLTIGGLGVF-KIAPIFK 137
            .::|||||||||||||.||||||::|:.|.|.:||:|:.||||:.||...:|.:.|: :..|:|:
  Fly    73 YSVGLGNVWRFPYLCYNNGGGAFLIPFTIMLVIAGLPLMFMELSFGQYAALGPVAVYRRFCPLFR 137

  Fly   138 GIGYAAAVMSCWMNVYYIVILAWAVFYFFMSMRADVPWRTCNNWWNTVNCVSQYERKNLHCWDKI 202
            |:|....::|..:.:||.:|:||.:||.|.|....:||:.|...|:|..|.| |.:.: .|  :.
  Fly   138 GLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAPVLPWQNCEPAWSTKYCFS-YAQAD-QC--EA 198

  Fly   203 INGTTQ-KVC----SVSALNITSLEL----TDPVKEFWERRALQISHGIEEIGNIRWELAGTLLL 258
            .|||.. :.|    |.:..|||:|.|    ..|.:|::....|.:|.||||.|:|:..||..|.|
  Fly   199 TNGTYYLRTCHNATSAAENNITTLALGALKRPPAEEYFNNFVLGLSKGIEETGSIKLSLAACLFL 263

  Fly   259 VWILCYFCIWKGVKWTGKVVYFTALFPYVLLTILLVRGITLPGALEGIKFYIIPNFSKLTNSEVW 323
            .|.:.:.|:.|||:.:|||||||||||||:|.||.|||:|||||..||.||:.|::.:|.|::||
  Fly   264 AWTIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFVRGVTLPGASTGILFYLTPDWKQLANAQVW 328

  Fly   324 IDAVTQIFFSYGLGLGTLVALGSYNKFTNNVYKDALIVCTVNSSTSMFAGFVIFSVIGFMAHEQQ 388
            .||..||||:.....|.|:.|.|||||:||.|||:|||...|.:||.|||.||||:|||:|||..
  Fly   329 GDAAVQIFFALSPAWGGLITLSSYNKFSNNCYKDSLIVAFCNIATSFFAGLVIFSIIGFLAHELN 393

  Fly   389 RPVADVAASGPGLAFLVYPSAVLQLPGSPMWSCLFFFMLLLIGLDSQFCTMEGFITAIIDEWPQL 453
            ..|..|...|.||||:|||..|.:||.||:|:.|||.|||.:||||||..||...|||:|.:|.
  Fly   394 VDVEKVVDQGAGLAFIVYPEVVTRLPVSPVWAVLFFVMLLTLGLDSQFALMETVTTAILDRFPN- 457

  Fly   454 LRKRKEIFIAIVCALSYLVGLTCITQGGMYIFQILDSYAVSGFCLLWLIFFECVSISWCYGVDRF 518
            ||:.|...:..|....|:.||...|..|||..|::|.|| :.:.:|.:...||:.|:|.||..||
  Fly   458 LRQYKIWVVLSVAIFGYIGGLGFTTNSGMYWLQLMDKYA-ANWSVLLIAISECILIAWIYGSQRF 521

  Fly   519 YDGIKDMIGYYPTVW---WKFCWCVTTPAICLGVFFFNIVQWTPVKYLDYSYPWWAHAFGWFTAL 580
            .:.|:.|||.....|   |...|...|||..|.:.|||.|::.|.||..|.||.||.|.||...|
  Fly   522 LNDIQGMIGKRSWFWNFFWGIMWRYITPATLLFILFFNWVEYKPAKYGHYVYPMWADAVGWIVGL 586

  Fly   581 SSMLYIPLYMFW-LWKRTPGELS--EKIRALVR 610
            ..:|.|.|..|. :| |.|..||  ::|:.|::
  Fly   587 LPVLVIFLVAFQEIW-RAPMSLSFRDRIKHLLQ 618

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	261/569 (46%)
GlyT	NP_611836.2	SNF	57..603	CDD:249680	255/552 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	1	1.000	-	-		FOG0000575
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920