DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gat and CG8850

DIOPT Version :9

Sequence 1:	NP_651930.2	Gene:	Gat / 43805	FlyBaseID:	FBgn0039915	Length:	636	Species:	Drosophila melanogaster
Sequence 2:	NP_725122.2	Gene:	CG8850 / 36331	FlyBaseID:	FBgn0033708	Length:	629	Species:	Drosophila melanogaster

Alignment Length:	577	Identity:	185/577 - (32%)
Similarity:	301/577 - (52%)	Gaps:	37/577 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 SKELGHTTSLQSSSPTTTDTSNKQQLVKIEQLPD----RGSWSSKMDFILSVVGLAIGLGNVWRF 84
            |:| ||..|....|........::..:..|...:    |..||..::|:.|.:.|::||||||||
  Fly    20 SRE-GHPGSNDGISTVIYSAEGEELTINCEAESESSGQRDQWSRGVEFLFSCIALSVGLGNVWRF 83

  Fly    85 PYLCYKNGGGAFILPYIITLFLAGIPMFFMELALGQMLTIGGLGVFKIAPIFKGIGYAAAVMSCW 149
            |::..:||||||::||:|.|.|.|.|::::|:.:||..:.|.:..|.:|||.:||.|.....:..
  Fly    84 PFIALENGGGAFLIPYVIVLLLIGRPVYYLEVIIGQFSSRGCIRAFDMAPIMRGIAYGQVYSTAL 148

  Fly   150 MNVYYIVILAWAVFYFFMSMRADVPWRTCNNWWNTVNCVSQYERKNLHCWDKIINGTTQKVCSVS 214
            ...||..|:|..:.|...|....:||..|...|.. :||:              .|.|....|..
  Fly   149 ATTYYACIMALTIRYLVASFSEVLPWTYCLVEWGK-SCVA--------------TGATAANDSSI 198

  Fly   215 ALNITSLELTDPVKEFWERRALQISHGIEE--IGNIRWELAGTLLLVWILCYFCIWKGVKWTGKV 277
            ...::|.||      |:.:..|:....:::  :|...|:|...||..|::....:.||::.:||.
  Fly   199 VQGVSSAEL------FFTQTVLREPESLDDNGLGTPSWDLVLCLLATWVIIGTILSKGIRSSGKA 257

  Fly   278 VYFTALFPYVLLTILLVRGITLPGALEGIKFYIIPNFSKLTNSEVWIDAVTQIFFSYGLGLGTLV 342
            .||.||||||::.:||:|.:|||||.:||.:::.|.:|:|.|..||..|:||:|||..:..||||
  Fly   258 SYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLKPQWSQLLNPHVWYAAITQMFFSLAICFGTLV 322

  Fly   343 ALGSYNKFTNNVYKDALIVCTVNSSTSMFAGFVIFSVIGFMAHE-QQRPVADVAASGPGLAFLVY 406
            ...|:|.|..||:||.:|:.|::|.||:.||.:||.::|.:|.| ..:.::.|...|.||||:.|
  Fly   323 MYASFNDFNKNVHKDVIIITTIDSLTSILAGCIIFGILGNLAFETNTKDISQVVKGGAGLAFISY 387

  Fly   407 PSAVLQLPGSP-MWSCLFFFMLLLIGLDSQFCTMEGFITAIIDEWPQLLRKRKEIFIAIVCALSY 470
            |.|:.:....| :::.|||||||::|:.|........:..:.|.:..|......:..:|:   .:
  Fly   388 PEAIAKFKYLPQLFAVLFFFMLLVLGIGSNIGMASAVVNVVKDRFTHLPHWLLAVSASII---GF 449

  Fly   471 LVGLTCITQGGMYIFQILDSYAVSGFCLLWLIFFECVSISWCYGVDRFYDGIKDMIGYYPTVWWK 535
            |.||..:|.||.::..::|.|..: |..|.|...|.:::.|.|||.|....|:.|:....:.:|:
  Fly   450 LCGLVYMTPGGQFVLNLVDFYGCT-FIALVLAIAELLAVGWIYGVKRICSDIEFMLNVKTSFYWR 513

  Fly   536 FCWCVTTPAICLGVFFFNIVQWTPVKYLDYSYPWWAHAFGWFTALSSMLYIPLYMFW 592
            .||.:..|.:...|..:.:..:.|:.|....||...:..||......:|.:|   ||
  Fly   514 ICWAIVAPGLMFLVLVYMLFSYEPLTYRGVQYPPVYYMAGWIIWGLGVLQLP---FW 567

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	178/539 (33%)
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	167/498 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440713
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850