DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gat and CG1698

DIOPT Version :9

Sequence 1:	NP_651930.2	Gene:	Gat / 43805	FlyBaseID:	FBgn0039915	Length:	636	Species:	Drosophila melanogaster
Sequence 2:	NP_001260835.1	Gene:	CG1698 / 36006	FlyBaseID:	FBgn0033443	Length:	654	Species:	Drosophila melanogaster

Alignment Length:	559	Identity:	199/559 - (35%)
Similarity:	308/559 - (55%)	Gaps:	48/559 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 RGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFILPYIITLFLAGIPMFFMELALGQML 122
            |.||::.::|::|.:.|::|||||||||:...:||||||::||:|.|.|.|.|::::|:.|||..
  Fly    74 RDSWNNDIEFLMSCIALSVGLGNVWRFPFTALENGGGAFVIPYLIVLILVGKPVYYLEMLLGQFS 138

  Fly   123 TIGGLGVFKIAPIFKGIGYAAAVMSCWMNVYYIVILAWAVFYFFMSMRADVPWRTCNNWWNTVNC 187
            :.|.:.|:..:||.:||||...:.:..:..||..::|..:.||..|....:||..|...|.|
  Fly   139 SRGSVKVYDFSPIMRGIGYGQVLATGIVTTYYATLMALTLRYFVDSFYPTLPWSYCREEWGT--- 200

  Fly   188 VSQYERKNLHCWDKIINGTTQKVCSVSALNITSLELTDPVKEFW-----ERRALQISHGIEEIGN 247
                     .|.|    ...|:....::|..:.:..|.  .||:     .|....|..|   ||.
  Fly   201 ---------ECLD----SGPQEASRATSLAGSGVRTTS--AEFYFTNIILREKASIDDG---IGY 247

  Fly   248 IRWELAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFPYVLLTILLVRGITLPGALEGIKFYIIP 312
            ..|.||..|.:.||:....::||||.:||..||.||||||::.:||||.:|||||.:|:.:::.|
  Fly   248 PSWSLALALAVAWIVIAGIMFKGVKSSGKASYFLALFPYVVMLVLLVRALTLPGAFDGVLYFLRP 312

  Fly   313 NFSKLTNSEVWIDAVTQIFFSYGLGLGTLVALGSYNKFTNNVYKDALIVCTVNSSTSMFAGFVIF 377
            .:.||...:||..||||:|||..:..|.::...|||:|.:|:|:||.||.|:::.||:.:|.:||
  Fly   313 QWHKLLEPQVWYAAVTQVFFSLAICFGNIIMYASYNRFGHNIYRDANIVTTLDTFTSLLSGVIIF 377

  Fly   378 SVIGFMAHEQQ-RPVADVAASGPGLAFLVYPSAVLQLPGSP-MWSCLFFFMLLLIGLDSQFCTME 440
            .::|.:|:|.. ..:|.|...||||||:.||.|:.:....| ::|.|||.||.::|:.|......
  Fly   378 GILGNLAYENNTTDIASVVNGGPGLAFISYPDAIAKFKWLPQLFSVLFFLMLFVLGIGSNVGMAS 442

  Fly   441 GFITAIIDEWPQLLRKRKEIFIAIVCALSYLVGLTCITQGGMYIFQILDSYAVSGFCLLWLIFFE 505
            ...|.|.|::..|......:.||||   .|.:||..||.||.::..::|.:.|: |..|.|..||
  Fly   443 CMSTVIKDQFGHLKNWTVVVGIAIV---GYFLGLLYITPGGQFLLNLVDYFGVT-FVALVLAIFE 503

  Fly   506 CVSISWCYGVDRFYDGIKDMIGYYPTVWWKFCWCVTTPAICLGVFFFNIVQWTPVKYLDYSYPWW 570
            .|:|:|.|||.|....::.|||...:::::.||.|.||.:.|.:..:.:|.:.|:||.||:|...
  Fly   504 LVTIAWIYGVKRLCRDVEFMIGIKTSLYYRICWAVVTPLLMLTILIYTLVLYEPLKYKDYTYQSG 568

  Fly   571 AHAFGWFTALSSMLYIPLYMFW-------------LWKR 596
            .:.|||   ..|...:...:||             ||.|
  Fly   569 VYVFGW---CLSAFGVGQVLFWAIPAVRKQPSHLGLWAR 604

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	199/559 (36%)
CG1698	NP_001260835.1	SLC6sbd	75..552	CDD:271359	182/501 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440711
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850