Protein Alignment Gat and Ntl

DIOPT Version :10

• Sequence 1: NP_651930.2
• Gene: Gat / 43805
• FlyBaseID: FBgn0039915
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_609135.1
• Gene: Ntl / 34046
• FlyBaseID: FBgn0267326
• Length: 590
• Species: Drosophila melanogaster
• Alignment Length: 603
• Identity: 230/603 - (38%)
• Similarity: 364/603 - (60%)
• Gaps: 34/603 - (5%)

  Fly    33 LQSSSPTTTDTSNKQQLVKIEQLPDRGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFI 97
            :.::.|.||:.:.|.:  :||:..:||.|.||.:||||::|.|||:|||||||||||::||.||:
  Fly     1 MANNQPPTTNATRKDK--RIERDENRGQWKSKSEFILSLLGYAIGIGNVWRFPYLCYRSGGAAFL 63

  Fly    98 LPYIITLFLAGIPMFFMELALGQMLTIGGLGVFKIAPIFKGIGYAAAVMSCWMNVYYIVILAWAV 162
            :||::.:.|||||:|:||:.:||..:.|..|:|::.|:.||.|.|..|::.:...||.||:::.:
  Fly    64 IPYLLMVILAGIPLFYMEILIGQFSSTGCTGMFRMTPLLKGTGIAQVVVNAYCVCYYSVIISYPI 128

  Fly   163 FYFFMSMRADVPWRTCNNWWNTVNCV--SQYERKNLHCWDKIINGTTQKVCSVSALNITSLELTD 225
            ...|......|||..|:|.|||.:||  |...::|           :..|...||
  Fly   129 RMIFYCFFKKVPWEDCSNSWNTDDCVTASDMGKQN-----------SSDVFKTSA---------- 172

  Fly   226 PVKEFWERRALQISHGIEEIGNIRWELAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFPYVLLT 290
              .||:....|:||..|.::|.:.||....|::.||:.|||:.:|:|..|||||||..|||:||.
  Fly   173 --DEFFHLEVLRISTDISDLGGMVWEQLTALIITWIIIYFCLMRGIKSVGKVVYFTVPFPYLLLF 235

  Fly   291 ILLVRGITLPGALEGIKFYIIPNFSKLTNSEVWIDAVTQIFFSYGLGLGTLVALGSYNKFTNNVY 355
            |||:||.|||||.:|||||:.|.:.:|.:.:||.||..|:||..|.|.|.:|.:.|::.|.||..
  Fly   236 ILLIRGATLPGAWKGIKFYLYPEWHRLLDLKVWADAAVQMFFGIGPGWGGIVNMASFSSFRNNAK 300

  Fly   356 KDALIVCTVNSSTSMFAGFVIFSVIGFMAHEQQRPVADVAASGPGLAFLVYPSAVLQLPGSPMWS 420
            .|::::.::|..||:.||||:|||:||::.:...||..||..|.||||:.||.|:..||...:|:
  Fly   301 CDSVLIVSINVFTSLLAGFVVFSVLGFLSEKSGIPVESVATGGAGLAFVTYPEAIALLPVPQLWA 365

  Fly   421 CLFFFMLLLIGLDSQFCTMEGFITAIIDEWPQLLRKRKEIFIAIVCALSYLVGLTCI--TQGGMY 483
            .:|||||.|:|:||.|..:|..:::|:||| ..:|..|.....|.|.:  .:||:.|  |.|||:
  Fly   366 LMFFFMLFLLGIDSVFVQLEAIMSSILDEW-YWVRSHKCKLTLISCLI--FLGLSSIMCTNGGMF 427

  Fly   484 IFQILDSYAVSGFCLLWLIFFECVSISWCYGVDRFYDGIKDMIGYYPTVWWKFCWCVTTPAICLG 548
            |.|:.|.|: |...::.:...|.:.::|.||:..|...::.|:|..||::|:..|.|.||.|.:.
  Fly   428 ILQLFDWYS-SAIAVIVICLVEIIMVAWIYGIKNFMLDVEFMLGKRPTLYWRIVWQVVTPVIIIF 491

  Fly   549 VFFFNIVQWTPVKYLDYSYPWWAHAFGWFTALSSMLYIPLYMFWLWKRTPGELSEKIRALVR-ID 612
            :...:||....:.|.:..||.||...||.:..:|:::||||:|::..|....|.:.::..:: :|
  Fly   492 ILITSIVFIRTITYNNIPYPQWAIIIGWASCFTSVMWIPLYIFYIMIRKRATLCDSLKKRLKPLD 556

  Fly   613 EDVTRLREKMLREAYAKE 630
            ......:::...||:.::
  Fly   557 WTPADPQDRAEYEAFRRQ 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	221/557 (40%)
Ntl	NP_609135.1	SLC5-6-like_sbd	24..554	CDD:444915	221/556 (40%)