Protein Alignment Gat and slc6a19b

DIOPT Version :9

• Sequence 1: NP_651930.2
• Gene: Gat / 43805
• FlyBaseID: FBgn0039915
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_956030.1
• Gene: slc6a19b / 326030
• ZFINID: ZDB-GENE-030131-4755
• Length: 651
• Species: Danio rerio
• Alignment Length: 667
• Identity: 214/667 - (32%)
• Similarity: 326/667 - (48%)
• Gaps: 130/667 - (19%)

  Fly    50 VKIEQLPDRGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFILPYIITLFLAGIPMFFM 114
            :::|:..||..|.:|..::|:.||..:||||||||||||..:|||||::|::|.|...|||:..:
Zfish    25 LEVEEAGDRPKWDNKAQYMLTCVGFCVGLGNVWRFPYLCQSHGGGAFMIPFLILLVFEGIPLLHL 89

  Fly   115 ELALGQMLTIGGLGVFK-IAPIFKGIGYAAAVMSCWMNVYYIVILAWAVFYFFMSMRADVPWRTC 178
            |.|:||.|..|.:||:: |.|...|:|.|:..:|..:::||..|:||.::|||.|.:..:||..|
Zfish    90 EFAIGQRLRKGSVGVWRTINPYMLGVGIASMCVSFLVSLYYNTIIAWVMWYFFNSFQDPLPWSQC 154

  Fly   179 NNWWNTVNCVSQYERKNLHCWDKIINGTTQKVCSVSALNITSLELTDPVKEFWERRALQISHGIE 243
            ....|....:.:                    |..|:          ||..||.|..|..|..|:
Zfish   155 PINENRTGPIPE--------------------CGKSS----------PVDYFWYRETLNTSAAID 189

  Fly   244 EIGNIRWELAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFPYVLLTILLVRGITLPGALEGIKF 308
            :.|.::..:...|:..|.:.|.|..:|::.|||.||.|:..||::|||.|:||:||.|:::||||
Zfish   190 DTGGLQVWMVLCLISAWAVLYVCCIRGIETTGKAVYVTSTLPYLVLTIFLIRGLTLKGSVDGIKF 254

  Fly   309 YIIPNFSKLTNSEVWIDAVTQIFFSYGLGLGTLVALGSYNKFTNNVYKDALIVCTVNSSTSMFAG 373
            ...|:.::|.|...|:||..|:|:|:.|..|.|::..|||...||..:||:|:..:|:.||::|.
Zfish   255 LFTPDINELANPSTWLDAGAQVFYSFSLAFGGLISFSSYNSVHNNCEQDAVIISVINAFTSIYAA 319

  Fly   374 FVIFSVIGFMAHEQ------------------------QRPVADVAAS----------------- 397
            .||:|:|||.|.|:                        |....||..|
Zfish   320 TVIYSIIGFRATERFDDCMNGNILTLLNTFDLPEGFINQSNYQDVFQSLNSTSPDIISSLSLKTC 384

  Fly   398 -----------GPGLAFLVYPSAVLQLPGSPMWSCLFFFMLLLIGLDSQFCTMEGFITAIID--- 448
                       |.||||:|:..|:.::|.||:||.|||.||..:||.|.|..:||.:..:.|
Zfish   385 DLNNFLSEGVEGTGLAFIVFTEAITKMPLSPLWSVLFFIMLFCLGLSSMFGNIEGVLVPLQDLGV 449

  Fly   449 ---EWPQLLRKRKEIFIAIVCALSYLVGLTCITQGGMYIFQILDSYAVSGFCLLWLIFFECVSIS 510
               .||      |||...:.|.:..||||..:...|.|...:.||:|.| ..||.:.|.|.:.:.
Zfish   450 FPKSWP------KEIISGVTCLVCCLVGLIFVQGSGNYWLALFDSFAGS-IPLLIIAFSEMIGVV 507

  Fly   511 WCYGVDRFYDGIKDMIGYYPTVWWKFCWCVTTPAICLGVFFFNIVQWTPVKYLDYS--------- 566
            :.||:|||.:.:..|||:.|.::|:..|...:|.|.|.:|.| ....|..|.:.||
Zfish   508 YVYGIDRFNEDLIFMIGHKPNIFWQATWRFISPLIMLAIFVF-YFSTTVTKEIFYSAWDPESENF 571

  Fly   567 -------YPWWAHAFGWFTALSSMLYIP-LYMF-----WLWKRTPGELSEKIRALVRI------- 611
                   ||.|.:...:..|....|.:| ..:|     :..|:.|   |..|:.|..:
Zfish   572 PTLEKKPYPTWIYVIIFLLAGVPSLAVPGTAVFRAIRDYCCKKHP---SASIQQLDSVSYKVQMH 633

  Fly   612 DEDV-TRLREKMLREAY 627
            ||:| |:..||..::.|
Zfish   634 DEEVKTQKTEKFDQKLY 650

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	205/633 (32%)
slc6a19b	NP_956030.1	SLC6sbd_B0AT1	33..613	CDD:212085	200/617 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810