Protein Alignment Gat and Slc6a14

DIOPT Version :10

• Sequence 1: NP_651930.2
• Gene: Gat / 43805
• FlyBaseID: FBgn0039915
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_038955501.1
• Gene: Slc6a14 / 298340
• RGDID: 1561810
• Length: 646
• Species: Rattus norvegicus
• Alignment Length: 621
• Identity: 257/621 - (41%)
• Similarity: 373/621 - (60%)
• Gaps: 41/621 - (6%)

  Fly    41 TDTSNKQQLVKIEQLPDRGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFILPYIITLF 105
            |.:|....:.:.::..:||:||.|.|::||:||.|:|||||||||||.|.||||||::||.|.|.
  Rat    25 TASSENFHVGENDENQERGNWSKKSDYLLSMVGYAVGLGNVWRFPYLTYTNGGGAFLIPYAIMLA 89

  Fly   106 LAGIPMFFMELALGQMLTIGGLGVFKIAPIFKGIGYAAAVMSCWMNVYYIVILAWAVFYFFMSMR 170
            |||:|:||:|.:|||..::|.:.|::|.|:|:|:|....::|.::.:||.||:|::::|.|.|.:
  Rat    90 LAGLPLFFLECSLGQFASLGPVSVWRILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYLFASFQ 154

  Fly   171 ADVPWRTCNNWWNTVNCVSQYERKNLHCWDKIINGTT----------QKVCSVSALNITSLELTD 225
            :.:||..|::.|...||..|          .|:.|..          ..:..|::.|.|.|..::
  Rat   155 SVLPWANCSSSWADDNCSRQ----------PIVTGCRVSTDTGGDMFMNISWVNSNNFTCLNGSE 209

  Fly   226 -------PVKEFWERRALQISHGIEEIGNIRWELAGTLLLVWILCYFCIWKGVKWTGKVVYFTAL 283
                   |.:::|::..|:.|.|::|.|.|.|.||..|||.||:....::||:|.:|||||||||
  Rat   210 VFRPGQLPSEQYWDKVTLRRSSGMDETGVIVWYLALCLLLAWIIVGAALFKGIKSSGKVVYFTAL 274

  Fly   284 FPYVLLTILLVRGITLPGALEGIKFYI--IPNFSKLTNSEVWIDAVTQIFFSYGLGLGTLVALGS 346
            ||||:|.|||:||.||.||.:||.:||  ..||:||..:|||.||.||||:|..:..|.||||.|
  Rat   275 FPYVVLLILLIRGATLEGASKGISYYIGAQSNFTKLREAEVWKDAATQIFYSLSVAWGGLVALSS 339

  Fly   347 YNKFTNNVYKDALIVCTVNSSTSMFAGFVIFSVIGFMAHEQQRPVADVAASGPGLAFLVYPSAVL 411
            ||||.||.|.||:|||..|..||:||||.|||::|.|||...:.|:.|..||..|||:.||.|:.
  Rat   340 YNKFNNNCYSDAIIVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGFDLAFIAYPEALA 404

  Fly   412 QLPGSPMWSCLFFFMLLLIGLDSQFCTMEGFITAIIDEWPQLLRKRKEIFIAIVCAL-SYLVGLT 475
            ||||.|.||.|||||||.:||||||.::|...|.|.|.:|:.: ||..:.|.:.|.| .:|:||.
  Rat   405 QLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKAM-KRMRVPITLGCCLILFLLGLV 468

  Fly   476 CITQGGMYIFQILDSYAVSGFCLLWLIFFECVSISWCYGVDRFYDGIKDMIG---YYPTVWWKFC 537
            |:||.|:|...::|.:. :|:.:|.....|...|.|.||.:||.:.|:.|||   :...:||:.|
  Rat   469 CVTQAGIYWVHLIDHFC-AGWGILIAAILEIAGIIWIYGGNRFIEDIEMMIGAKRWLFWLWWRAC 532

  Fly   538 WCVTTPAICLGVFFFNIVQWTPVKYLDYSYPWWAHAFGWFTALSSMLYIPLYMFWLWKRTPGELS 602
            |.|.||.:...:..:::|::....|.|..||.|..|.||...:..:::||:.......|..|.:.
  Rat   533 WFVITPILLSAILVWSLVKFHRPNYADIPYPDWGVALGWCMIIFCIIWIPIMAIIKIVRAEGNIL 597

  Fly   603 EKIRALVRIDEDVTRLREKMLREAY------AKEIE 632
            ::|....|...:.....||...|.|      |||.:
  Rat   598 QRIIKCCRPASNWGPYLEKHRGERYKDMAEPAKETD 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	247/575 (43%)
Slc6a14	XP_038955501.1	SLC6sbd_ATB0	42..645	CDD:271391	255/604 (42%)