Protein Alignment Gat and Slc6a16

DIOPT Version :9

• Sequence 1: NP_651930.2
• Gene: Gat / 43805
• FlyBaseID: FBgn0039915
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_038949993.1
• Gene: Slc6a16 / 292902
• RGDID: 1561338
• Length: 850
• Species: Rattus norvegicus
• Alignment Length: 658
• Identity: 155/658 - (23%)
• Similarity: 276/658 - (41%)
• Gaps: 136/658 - (20%)

  Fly    32 SLQSSSPTTT----DTSNKQQL-VKIEQLPDRGS--------WSSKMDFILSVVGLAIGLGNVWR 83
            :||.:.|:||    :|:.||:. :::.:.....|        ||||.::||:::|..:....:.|
  Rat   193 ALQFNKPSTTEYSMETTPKQESPIELNKTSKENSNVFPPWLLWSSKAEYILALMGYLVMPSGLLR 257

  Fly    84 FPYLCYKNGGGAFILPYIITLFLAGIPMFFMELALGQMLTIGGLGVFK-IAPIFKGIGYAAAVMS 147
            |.......|..:|.:.|::.||..|||:.|:|:|:||......:.::| ::|.|.|:||:..::.
  Rat   258 FVTCWVHKGSWSFFIAYLLMLFGLGIPLLFLEMAVGQRAQQSSIDLWKTLSPWFGGLGYSMVMVC 322

  Fly   148 CWMNVYYIVILAWAVFYFFMSMRADVPWRTCNNWWNTVNCVSQYERKNLHCWDKIINGTTQKVCS 212
            ...|.|..|..:|.:||........|||..|....|:.:...:.|:...:.:
  Rat   323 LITNTYLNVFNSWILFYMSHIFHFVVPWDRCPLQKNSSDFDPECEQATSYTY------------- 374

  Fly   213 VSALNITSLELTDPVKEFWERRALQISHGIEEIGNIRWELAGTLLLVW-ILCYFCIWKGVKWTGK 276
                             ||.|:.|:.|..||:.|...:.||..|.|.| ::|.|.: .|:|..||
  Rat   375 -----------------FWYRQTLKASDSIEDGGQPSFNLAMFLFLAWCLICVFMV-NGIKSLGK 421

  Fly   277 VVYFTALFPYVLLTILLVRGITLPGAL-EGIKFYIIPNFSKLTNSEVWIDAVTQIFFSYGLGLGT 340
            |:......||.::...|||.:::...: .|:.:.:|...:::::..:|..|..|:.|..|||.|.
  Rat   422 VLCVLLQVPYFIIICFLVRTLSMGNGIGYGLNYLLILEVARISDLTMWCQAGIQVLFDIGLGFGP 486

  Fly   341 LVALGSYNKFTNNVYKDALIVCTVNSSTSMFAGFVIFSVIGFMA--------------------- 384
            :::|.|:....||..|||.::......|.:.......|::||.|
  Rat   487 VISLSSHMSDFNNCLKDAFLMGLFKIVTLLITTPFFLSILGFWATITTHHCCKKNTNKLLMLIAQ 551

  Fly   385 ------------------------HEQQRPVADVAAS----------------GPGLAFLVYPSA 409
                                    :....|:.....|                .|...||::...
  Rat   552 GILPPEVEPPDLNDDPISIYNSWLNSLPPPLRSAVLSMVPECNIQKQFMRIEDSPRFLFLIFTEV 616

  Fly   410 VLQLPGSPMWSCLFFFMLLLIGLDSQFCTMEGFITAIIDEWPQLLRKRKEIFIAIVCALSYLVGL 474
            :..||||..|:.|||..||.:||.:....|.|.|..:.|.:| ..|::..:....|...::|.||
  Rat   617 ISLLPGSAFWTVLFFLALLGLGLCTNLMYMLGNILTLQDTFP-FCRRQPRLLTVGVSMTTFLCGL 680

  Fly   475 TCITQGGMYIFQILDSYAVSGFCLLWLIFFECVSISWCYGVDRFYDGIKDMIG-----YYPTVWW 534
            ..|...|:|.|.:|..|.|: ..::.:|..|.::::|.||..||   :.||:.     .:|...|
  Rat   681 IFIQPSGIYYFSLLSEYWVA-VPIITIILCETLAVAWAYGAKRF---LADMMALLSRPIFPGCSW 741

  Fly   535 KFCWCVTTPAICLGVFFF---NIVQWTPVKYLDYS----------YPWWAHAFGWFTALSSMLYI 586
              .|...:|.:.||:..|   .:|| .|:.|:.:.          :|.|:...  ...||:::.:
  Rat   742 --LWRYVSPVVLLGLLLFICIYLVQ-GPLVYMAWDSSTSKEVVRYFPMWSLML--IAGLSAVVLM 801

  Fly   587 PLYMFWLW 594
            |:..::.:
  Rat   802 PIPAYFAY 809

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	147/627 (23%)
Slc6a16	XP_038949993.1	SLC6sbd_NTT5	232..802	CDD:271392	145/610 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920