Protein Alignment Gat and Slc6a20b

DIOPT Version :10

• Sequence 1: NP_651930.2
• Gene: Gat / 43805
• FlyBaseID: FBgn0039915
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_035861.2
• Gene: Slc6a20b / 22599
• MGIID: 1336891
• Length: 635
• Species: Mus musculus
• Alignment Length: 619
• Identity: 201/619 - (32%)
• Similarity: 302/619 - (48%)
• Gaps: 104/619 - (16%)

  Fly    38 PTTTDTSNKQQLVKIEQLPDRGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFILPYII 102
            |.:|:.::...:.|:     |..|.:.:.|:|..:..|:||||||||||||...|||:|::||||
Mouse    33 PRSTECAHPGVVEKV-----RPKWDNPLQFLLVCISYAVGLGNVWRFPYLCQMYGGGSFLVPYII 92

  Fly   103 TLFLAGIPMFFMELALGQMLTIGGLGVFK-IAPIFKGIGYAAAVMSCWMNVYYIVILAWAVFYFF 166
            .|.:.|:|:.::|||:||.:..|.:|.:: |:|...|:|.|:.|:|...:||:.||..||::|.|
Mouse    93 MLIVEGMPLLYLELAVGQRMRQGSIGAWRTISPYLSGVGIASLVVSFLASVYFNVINTWALWYLF 157

  Fly   167 MSMRADVPWRTCNNWWNTVNCVSQYERKNLHCWDKIINGTTQKVCSVSALNITSLELTDPVKEFW 231
            .|.:..:||..|     .:|  |.:...:..|                       |.....:.||
Mouse   158 HSFQDPLPWSVC-----PLN--SNHTGYDEEC-----------------------EKASSTQYFW 192

  Fly   232 ERRALQISHGIEEIGNIRWELAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFPYVLLTILLVRG 296
            .|:.|.||..|:|.|.::||.|..|.|.|::.|.||.:|.:.||||||||...||.:|.|.||||
Mouse   193 YRKTLNISPSIQENGGVQWEPALCLTLAWLMVYLCILRGTESTGKVVYFTTSLPYFVLIIYLVRG 257

  Fly   297 ITLPGALEGIKFYIIPNFSKLTNSEVWIDAVTQIFFSYGLGLGTLVALGSYNKFTNNVYKDALIV 361
            :||.||..|:.:...|...:|.|.:.||:|.||||||.|||.|.|:|..|||:.:|:..|.||||
Mouse   258 LTLHGATNGLAYMFTPKIEQLANPKAWINAATQIFFSLGLGCGGLIAFASYNEPSNDCQKHALIV 322

  Fly   362 CTVNSSTSMFAGFVIFSVIGFMA-------------------------------HEQQRPVA--- 392
            ..:||:|::|:..|.||:.||.|                               .|.:..:|
Mouse   323 SVINSTTAIFSSIVTFSIYGFKATFNYENCLNKVILLLTNSFDLEDGFLTVSNLEEVKNYLASTY 387

  Fly   393 --------------------DVAASGPGLAFLVYPSAVLQLPGSPMWSCLFFFMLLLIGLDSQFC 437
                                |.|..|.||||:||..|:..:..|.:||.|:|||||.:|:.|...
Mouse   388 PNKYSEVFPHIRNCSLESELDTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLTLGMGSMVG 452

  Fly   438 TMEGFITAIIDEWPQLLRKRKEIFIAIVCALSYLVGLTCITQGGMYIFQILDSYAVSGFCLLWLI 502
            |....:|.:.|.........||....:||.|:..:|:....:.|.|.|.:.:.|..: ..||.::
Mouse   453 TGTAILTPLTDSKIISSYLPKEAISGLVCLLNCAIGMVFTMEAGNYWFDLFNDYTAT-LSLLLIV 516

  Fly   503 FFECVSISWCYGVDRFYDGIKDMIGYYPTVWWKFCWCVTTPAICLGVFFFNIVQWTPVKYLDY-- 565
            ..|.:::.:.||:.||...::.|.|...:.:||..|...:|.:.:|:|.|.:..:.....|.|
Mouse   517 LVETIAVCYVYGLKRFESDLRAMTGRTLSWYWKVMWAFVSPLLIVGLFIFYLSDYILTGTLQYQA 581

  Fly   566 -----------SYPWWAHAFGWFTALSSMLYIPL 588
                       .||.:|.|.......||.:.|||
Mouse   582 WDATQGHVVTKDYPTYALAVIGLLVASSTMCIPL 615

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	198/599 (33%)
Slc6a20b	NP_035861.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..38		2/4 (50%)
		SLC5-6-like_sbd	45..620	CDD:444915	199/607 (33%)