Protein Alignment Gat and snf-2

DIOPT Version :9

• Sequence 1: NP_651930.2
• Gene: Gat / 43805
• FlyBaseID: FBgn0039915
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_492396.2
• Gene: snf-2 / 172701
• WormBaseID: WBGene00004901
• Length: 746
• Species: Caenorhabditis elegans
• Alignment Length: 584
• Identity: 175/584 - (29%)
• Similarity: 296/584 - (50%)
• Gaps: 59/584 - (10%)

  Fly    50 VKIEQLPDRGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFILPYIITLFLAGIPMFFM 114
            :::|. .||.::.. ::.:||.:|.||||||:||||.:.|:|||.:|::.|||..|:..:|...|
 Worm   102 IQVEN-TDRQAFRG-IESLLSSLGQAIGLGNIWRFPTVAYQNGGTSFLIVYIICAFVFAVPAIHM 164

  Fly   115 ELALGQMLTIGGLGVF-KIAPIFKGIGYAAAVMSCWMNVYYIVILAWAVFY----FFMSMRADVP 174
            |.||||........|| :|.|..:|:|:...::...:.|||:::::|.|.|    |:::...
 Worm   165 EFALGQYAAKSPPAVFRRIMPALEGVGWMTCIVGAVIGVYYMILISWIVLYIINIFYVNNMG--- 226

  Fly   175 WRTCNNWWNTVNCV--SQYERKNLHCWDKI-------INGTTQKVCSVSALNI----------TS 220
              .|:|.||..||.  |:..|.|...:..:       :|.|...:.|..:..|          |:
 Worm   227 --RCDNPWNQNNCYDGSEQSRCNKGLYSNMTANASSFLNTTMAPLMSSGSKRILYINGKCQDATN 289

  Fly   221 LELTDPVKEFWERRALQISHGIEEIGNIRWELAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFP 285
            :.:....::|:.:..::.|.|..:..:|...:.|.:.|.|::....:.:|:|..||:.|.|.:.|
 Worm   290 MSVEVGTEQFFSKSVIRPSAGFTDFNSINLPILGAVALCWVIAAVVLIRGMKAIGKLSYVTVILP 354

  Fly   286 YVLLTILLVRGITLPGALEGIKFYII--PNFSKLTNSEVWIDAVTQIFFSYGLGLGTLVALGSYN 348
            |.::..||:.|::||||.:|: :::.  .:|:.|...|.|..|:.||.||..:|.|.|:.:.|||
 Worm   355 YFIIVSLLICGVSLPGAKDGL-YHLFGQTDFNYLYKRETWTAALQQICFSLSIGQGGLMNIASYN 418

  Fly   349 KFTNNVYKDALIVCTVNSSTSMFAGFVIFSVIGFMAHEQQRPVADVAA------SGPGLAFLVYP 407
            |.|.|.|:|..|:..:::..|:..|..:||.:||:|:|:.....|:.|      .|..|||:||.
 Worm   419 KKTYNWYRDVYIIVFLDTLMSILGGITVFSTLGFLAYERGINSTDIDAFNHIVKEGHALAFIVYT 483

  Fly   408 SAVLQLPGSPMWSCLFFFMLLLIGLDSQFCTMEGFITAIIDEWPQLLRKRKEIFIAIVCALSYLV 472
            .|:.::|...:|..|||.||.|:|:.::...:|...:.:.|.: :.||:|:.:.:..|.|:.:|:
 Worm   484 EAIAEMPVPYLWYALFFIMLFLLGISTEVVIVEIVCSCLADRF-RYLRERRWLTVLSVSAVFFLL 547

  Fly   473 GLTCITQGGMYIFQILDSYAVSGFCLLWLIFFECVSISWCYGVDRFYDGIKDMIGYYPTVW---- 533
            ||...|..|.|.|.:.|.|: :|....:.....|:::.||||.:.|.:.|..|.| .|..|
 Worm   548 GLVMTTDAGFYWFDMFDEYS-TGISATFGTAIMCMTVFWCYGTNHFREDIAVMWG-EPESWLATC 610

  Fly   534 -------WKFCWCVTTPAICLGVFFFNIVQWT---PVKYLDYSYPWWAHAFGWFTALSSMLYIP 587
                   |...|...|| :| .:....:..|.   |.|.....||....|.|||.|:...|.||
 Worm   611 LGPAAYFWTLIWKFVTP-VC-SLLMMGLWIWEKKYPHKGDGKIYPPVFDALGWFIAVVPFLVIP 672

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	173/576 (30%)
snf-2	NP_492396.2	SLC6sbd	113..638	CDD:271359	159/536 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820