Protein Alignment Gat and mod-5

DIOPT Version :9

• Sequence 1: NP_651930.2
• Gene: Gat / 43805
• FlyBaseID: FBgn0039915
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_491095.3
• Gene: mod-5 / 171879
• WormBaseID: WBGene00003387
• Length: 671
• Species: Caenorhabditis elegans
• Alignment Length: 565
• Identity: 217/565 - (38%)
• Similarity: 340/565 - (60%)
• Gaps: 46/565 - (8%)

  Fly    58 RGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFILPYIITLFLAGIPMFFMELALGQML 122
            |..|::||:|:|:|||.|:.|||:||||.:|||:|||||::||.|.|.:.|:|||:|||.|||..
 Worm   100 RDKWATKMEFLLAVVGYAVDLGNIWRFPSVCYKHGGGAFLIPYFIMLMIGGLPMFYMELVLGQFH 164

  Fly   123 TIGGLGVF-KIAPIFKGIGYAAAVMSCWMNVYYIVILAWAVFYFFMSMR----ADVPWRTCNNWW 182
            ..|.:.:: |:.|:|:||||....:..::.::|..|:|.||::..:|:.    ::|||.:|.|.|
 Worm   165 RSGCVSIWRKVCPLFRGIGYGICCICTFIAIFYNAIIAQAVYFAIVSLSKIWDSEVPWASCGNPW 229

  Fly   183 NTVNCVSQYERKNLHCWDKIINGTTQKVCSVSALNIT----SLELTDPVKEFWERRALQI--SHG 241
            ||..|...                         ||:|    ...||.|.:|::..:.|::  |.|
 Worm   230 NTPRCSDD-------------------------LNVTISRNGTPLTTPSEEYYLYKVLEVQKSTG 269

  Fly   242 IEEIGNIRWELAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFPYVLLTILLVRGITLPGALEGI 306
            .:::|.::..:|..||.|:|:.||.:|||.:.:||:|:.||..||::|:|||:||:.||||..|:
 Worm   270 FDDLGGVKTSMAVCLLAVFIMVYFALWKGPQSSGKIVWVTATAPYIILSILLIRGLLLPGAKNGL 334

  Fly   307 KFYIIPNFSKLTNSEVWIDAVTQIFFSYGLGLGTLVALGSYNKFTNNVYKDALIVCTVNSSTSMF 371
            .:|:.|:|.||.:..||..|.||||||.|.|.|.|:||.|||.|.||.|:||:....:|.:||.|
 Worm   335 YYYVTPDFEKLKDPAVWSAAATQIFFSLGPGFGVLLALSSYNDFNNNCYRDAVTTSIINCATSFF 399

  Fly   372 AGFVIFSVIGFMAHEQQRPVADVAAS-GPGLAFLVYPSAVLQLPGSPMWSCLFFFMLLLIGLDSQ 435
            :|.|:||.:|:|:....:|:.:|... ...|.|:|||.|:..:..|..||.:||.||:.:|:||.
 Worm   400 SGCVVFSTLGYMSLLTNKPINEVVGEHDASLIFIVYPQALATMDYSCFWSFIFFVMLITLGIDST 464

  Fly   436 FCTMEGFITAIIDEWPQLLRKRKEIFIAIVCALSYLVGLTCITQGGMYIFQILDSYAVSGFCLLW 500
            |..:|.|||...|| .:.|.|.::.|:.::|.:.|.:....|:.||.::...||.|.|| ..:|:
 Worm   465 FAGIEAFITGFCDE-SRFLSKNRKWFVLVICIIYYFLSFPAISYGGQFVIPFLDEYGVS-LSVLF 527

  Fly   501 LIFFECVSISWCYGVDRFYDGIKDMIGYYPTVWWKFCWCVTTPAICLGVFFFNIV---QWTPVKY 562
            ::..|.:::.|.||||:|...|:.|:|:||.::|:.||  |...:.:.|.|...|   .:.|::.
 Worm   528 IVTCEMIAVCWFYGVDQFSKDIRAMLGFYPGIYWRVCW--TCSPVFISVIFIMTVYNSSFKPIQM 590

  Fly   563 LDYSYPWWAHAFGWFTALSSMLYIPLY-MFWLWKRTPGELSEKIR 606
            ..|::|||:...|||..|.|:|.||:: :.:|...| |.|.|:.|
 Worm   591 ASYTFPWWSVILGWFLRLLSVLAIPVFAIIYLLSGT-GTLYERFR 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	217/565 (38%)
mod-5	NP_491095.3	SLC6sbd_SERT-like	100..639	CDD:271388	217/565 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820