Protein Alignment Gat and Slc6a13

DIOPT Version :10

• Sequence 1: NP_651930.2
• Gene: Gat / 43805
• FlyBaseID: FBgn0039915
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_006237280.2
• Gene: Slc6a13 / 171163
• RGDID: 620788
• Length: 608
• Species: Rattus norvegicus
• Alignment Length: 594
• Identity: 309/594 - (52%)
• Similarity: 420/594 - (70%)
• Gaps: 34/594 - (5%)

  Fly    37 SPTTTDTSNKQQLVKIEQLPDRGS-----WSSKMDFILSVVGLAIGLGNVWRFPYLCYKNGGGAF 96
            |.||::...|.....:|::.:.|:     |::||:|:|||.|..|||||||||||||||||||||
  Rat     6 SGTTSNGETKPVCPVMEKVEEDGTLEREQWTNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAF 70

  Fly    97 ILPYIITLFLAGIPMFFMELALGQMLTIGGLGVF-KIAPIFK------GIGYAAAVMSCWMNVYY 154
            .:||:|.||..|||:||:|.||||....||:..: ||.|||:      |||||:.::...:||||
  Rat    71 FIPYLIFLFTCGIPVFFLETALGQYTNQGGITAWRKICPIFEASVPSPGIGYASQMIVSLLNVYY 135

  Fly   155 IVILAWAVFYFFMSMRADVPWRTCNNWWNTVNCVSQYERKNLHCWDKIINGTTQKVCSVSALNIT 219
            ||:||||:||.|.|...|:||.:|::.|||.||| ::::.|                  ::||:|
  Rat   136 IVVLAWALFYLFSSFTTDLPWGSCSHEWNTENCV-EFQKTN------------------NSLNVT 181

  Fly   220 SLELTDPVKEFWERRALQISHGIEEIGNIRWELAGTLLLVWILCYFCIWKGVKWTGKVVYFTALF 284
            |...|.||.||||||.|:||.||:.:|::||||...|||.||:||||||||||.|||||||||.|
  Rat   182 SENATSPVIEFWERRVLKISDGIQHLGSLRWELVLCLLLAWIICYFCIWKGVKSTGKVVYFTATF 246

  Fly   285 PYVLLTILLVRGITLPGALEGIKFYIIPNFSKLTNSEVWIDAVTQIFFSYGLGLGTLVALGSYNK 349
            ||::|.:||:||:|||||.:||:||:.||.::|.:.:||:||.||||||:.:.||.|.|||||||
  Rat   247 PYLMLVVLLIRGVTLPGAAQGIQFYLYPNITRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNK 311

  Fly   350 FTNNVYKDALIVCTVNSSTSMFAGFVIFSVIGFMAHEQQRPVADVAASGPGLAFLVYPSAVLQLP 414
            :.||.|:|.:.:|.:|||||..|||.|||::|||:.||..|:::||.|||||||:.||.||:.||
  Rat   312 YHNNCYRDCVALCILNSSTSFVAGFAIFSILGFMSQEQGVPISEVAESGPGLAFIAYPRAVVMLP 376

  Fly   415 GSPMWSCLFFFMLLLIGLDSQFCTMEGFITAIIDEWPQLLRK--RKEIFIAIVCALSYLVGLTCI 477
            .||:|:|.||||::|:||||||..:|..:||::|.:|::.||  |:||.|.||..:|:.:||..:
  Rat   377 FSPLWACCFFFMVVLLGLDSQFVCVESLVTALVDMYPRVFRKKNRREILILIVSVVSFFIGLIML 441

  Fly   478 TQGGMYIFQILDSYAVSGFCLLWLIFFECVSISWCYGVDRFYDGIKDMIGYYPTVWWKFCWCVTT 542
            |:||||:||:.|.||.||.|||::..||.:.::|.||..||||.|:|||||.|....|:||...|
  Rat   442 TEGGMYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGASRFYDNIEDMIGYKPWPLIKYCWLFFT 506

  Fly   543 PAICLGVFFFNIVQWTPVKY-LDYSYPWWAHAFGWFTALSSMLYIPLYMFWLWKRTPGELSEKIR 606
            ||:||..|.|:::::||:.| ..|:||||..|.||..|||||:.||.:..:..:...|.|.|::|
  Rat   507 PAVCLATFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALSSMVCIPAWSIYKLRTLKGPLRERLR 571

  Fly   607 ALVRIDEDV 615
            .||...||:
  Rat   572 QLVCPAEDL 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	302/567 (53%)
Slc6a13	XP_006237280.2	SLC5-6-like_sbd	32..581	CDD:444915	303/568 (53%)