Protein Alignment Gat and Slc6a5

DIOPT Version :10

• Sequence 1: NP_651930.2
• Gene: Gat / 43805
• FlyBaseID: FBgn0039915
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_063131123.1
• Gene: Slc6a5 / 171148
• RGDID: 621824
• Length: 812
• Species: Rattus norvegicus
• Alignment Length: 594
• Identity: 267/594 - (44%)
• Similarity: 377/594 - (63%)
• Gaps: 24/594 - (4%)

  Fly    28 GHTTSLQSSSPTTTDTSNKQQLVKIEQLPDRGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNG 92
            |..:.|..|..|||...::|.    ::...||:||||:|||||:||.|:|||||||||||.::||
  Rat   180 GIASVLPGSVATTTIPEDEQG----DENKARGNWSSKLDFILSMVGYAVGLGNVWRFPYLAFQNG 240

  Fly    93 GGAFILPYIITLFLAGIPMFFMELALGQMLTIGGLGVFKIAPIFKGIGYAAAVMSCWMNVYYIVI 157
            ||||::||::.|.|||:|:||:|::|||..:.|.:.|:|..|..:|.|.|..::|..:.:||.||
  Rat   241 GGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLIISVLIAIYYNVI 305

  Fly   158 LAWAVFYFFMSMRADVPWRTCNNWWNTVNCVSQYERKNLHCWDKIINGTTQKV-------CSVSA 215
            :.:.:||.|.|..:.:||.:|||.|||..|    :.|.....|..:.|...|:       |..:.
  Rat   306 ICYTLFYLFASFVSVLPWGSCNNPWNTPEC----KDKTKLLLDSCVIGDHPKIQIKNSTFCMTAY 366

  Fly   216 LNITSLELTDPV--------KEFWERRALQISHGIEEIGNIRWELAGTLLLVWILCYFCIWKGVK 272
            .|:|.:..|...        :|:::...|:||.|||..|.|||.||..|.|.|::.|..:.||:|
  Rat   367 PNLTMVNFTSQANKTFVSGSEEYFKYFVLKISAGIEYPGEIRWPLAFCLFLAWVIVYASLAKGIK 431

  Fly   273 WTGKVVYFTALFPYVLLTILLVRGITLPGALEGIKFYIIPNFSKLTNSEVWIDAVTQIFFSYGLG 337
            .:||||||||.||||:|.|||:||:|||||..||.::|.|.:.|||::.||.||.||||||....
  Rat   432 TSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKWEKLTDATVWKDAATQIFFSLSAA 496

  Fly   338 LGTLVALGSYNKFTNNVYKDALIVCTVNSSTSMFAGFVIFSVIGFMAHEQQRPVADVAASGPGLA 402
            .|.|:.|.|||||.||.|:|.|||...||:||:||||||||||||||:|::..:.:||..|||:|
  Rat   497 WGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSVIGFMANERKVNIENVADQGPGIA 561

  Fly   403 FLVYPSAVLQLPGSPMWSCLFFFMLLLIGLDSQFCTMEGFITAIIDEWPQLLRKRKEIFIAIVCA 467
            |:|||.|:.:||.||.|:.:||.|||.:|||:.|.|:|..:|:|.||:|:.||..|.:|....|.
  Rat   562 FVVYPEALTRLPLSPFWAIIFFLMLLTLGLDTMFATIETIVTSISDEFPKYLRTHKPVFTLGCCI 626

  Fly   468 LSYLVGLTCITQGGMYIFQILDSYAVSGFCLLWLIFFECVSISWCYGVDRFYDGIKDMIGYYPTV 532
            ..:::|...|||||:|:||::|:||.| :.|:.:..||.|.||:.||:.||.:.|:.|||:.|.:
  Rat   627 CFFIMGFPMITQGGIYMFQLVDTYAAS-YALVIIAIFELVGISYVYGLQRFCEDIEMMIGFQPNI 690

  Fly   533 WWKFCWCVTTPAICLGVFFFNIVQWTPVKYLDYSYPWWAHAFGWFTALSSMLYIPLYMFWLWKRT 597
            :||.||...||.|...:..|:..||.|:.|..|.||.|:...||.....|:::||:.........
  Rat   691 FWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMVLGWLMLACSVIWIPIMFVIKMYLA 755

  Fly   598 PGELSEKIR 606
            ||...|:::
  Rat   756 PGRFIERLK 764

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	260/564 (46%)
Slc6a5	XP_063131123.1	None