Protein Alignment Gat and Slc6a20a

DIOPT Version :10

• Sequence 1: NP_651930.2
• Gene: Gat / 43805
• FlyBaseID: FBgn0039915
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: NP_579830.2
• Gene: Slc6a20a / 113918
• RGDID: 621651
• Length: 616
• Species: Rattus norvegicus
• Alignment Length: 600
• Identity: 203/600 - (33%)
• Similarity: 295/600 - (49%)
• Gaps: 101/600 - (16%)

  Fly    58 RGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFILPYIITLFLAGIPMFFMELALGQML 122
            |..|.:.:.|:.:.:..|:||||||||||||...|||:|::||:|.|.:.|:|:.::|||:||.:
  Rat    29 RPQWGNPLQFVFACISYAVGLGNVWRFPYLCQMYGGGSFLVPYLIMLIVEGMPLLYLELAVGQRM 93

  Fly   123 TIGGLGVFK-IAPIFKGIGYAAAVMSCWMNVYYIVILAWAVFYFFMSMRADVPWRTCNNWWNTVN 186
            ..|.:|.:: |:|...|:|.|:.|:|.::::||.||.||..:|.|.|.:..:||..|     .:|
  Rat    94 RQGSIGAWRTISPYLSGVGVASVVVSFFLSMYYNVINAWGFWYLFHSFQDPLPWSVC-----PLN 153

  Fly   187 CVSQYERKNLHCWDKIINGTTQKVCSVSALNITSLELTDPVKEFWERRALQISHGIEEIGNIRWE 251
                   .|...:|:                  ..|.....:.||.|:.|.||..|:|.|.::||
  Rat   154 -------SNRTGYDE------------------ECEKASSTQYFWYRKTLNISPSIQENGGVQWE 193

  Fly   252 LAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFPYVLLTILLVRGITLPGALEGIKFYIIPNFSK 316
            .|..|.|.|::.|.||.:|.:.||||||||||.||.:|.|.||||:||.||..|:.:...|...:
  Rat   194 PALCLTLAWLMVYLCILRGTESTGKVVYFTALMPYCVLIIYLVRGLTLHGATNGLMYMFTPKMEQ 258

  Fly   317 LTNSEVWIDAVTQIFFSYGLGLGTLVALGSYNKFTNNVYKDALIVCTVNSSTSMFAGFVIFSVIG 381
            |.|.:.||:|.||||||.|||.|:|:|..|||:.:|:..|.|:||..:|||||:||..|.||:.|
  Rat   259 LANPKAWINAATQIFFSLGLGFGSLIAFASYNEPSNDCQKHAVIVSVINSSTSIFASIVTFSIYG 323

  Fly   382 FMA---------------------------HEQQRPVADVAAS---------------------- 397
            |.|                           ......|.|..||
  Rat   324 FKATFNYENCLNKVILLLTNSFDLEDGFLTASNLEEVKDYLASTYPNKYSEVFPHIRNCSLESEL 388

  Fly   398 -----GPGLAFLVYPSAVLQLPGSPMWSCLFFFMLLLIGLDSQFCTMEGFITAIIDEWPQLLRKR 457
                 |.||||:||..|:..:..|.:||.|:|||||::|:.|........:|.:.|.........
  Rat   389 NTAVQGTGLAFIVYTEAIKNMEVSQLWSVLYFFMLLMLGMGSMLGNTAAILTPLTDSKVISSYLP 453

  Fly   458 KEIFIAIVCALSYLVGLTCITQGGMYIFQILDSYAVSGFCLLWLIFFECVSISWCYGVDRFYDGI 522
            ||....:||.::..||:....:.|.|.|.|.:.||.: ..||.::..|.:::.:.||:.||...:
  Rat   454 KEAISGLVCLINCAVGMVFTMEAGNYWFDIFNDYAAT-LSLLLIVLVETIAVCYVYGLRRFESDL 517

  Fly   523 KDMIGYYPTVW-WKFCWCVTTPAICLGVFFFNIVQWTPVKYLDY-------------SYPWWAHA 573
            :.|.| .|..| ||..|...:|.:.:|:|.|.:..:.....|.|             .||..|.|
  Rat   518 RAMTG-RPLNWYWKAMWAFVSPLLIIGLFIFYLSDYILTGTLQYQAWDATQGQLVTKDYPPHALA 581

  Fly   574 FGWFTALSSMLYIPL 588
            .......||.:.|||
  Rat   582 VIGLLVASSTMCIPL 596

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	202/599 (34%)
Slc6a20a	NP_579830.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26
		SLC5-6-like_sbd	26..601	CDD:444915	202/599 (34%)