Protein Alignment Gat and slc6a4

DIOPT Version :9

• Sequence 1: NP_651930.2
• Gene: Gat / 43805
• FlyBaseID: FBgn0039915
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_017946918.1
• Gene: slc6a4 / 100493853
• XenbaseID: XB-GENE-22062972
• Length: 664
• Species: Xenopus tropicalis
• Alignment Length: 640
• Identity: 253/640 - (39%)
• Similarity: 390/640 - (60%)
• Gaps: 63/640 - (9%)

  Fly    16 CKHESIEMSKEL-------------GHTT----SLQS---------------SSPT-TTDTSNKQ 47
            || .|:.:|:||             ||.:    ::||               |:|| |...:.:.
 Frog    38 CK-PSLRLSEELNKVHPSPGERGEPGHISNKYLAVQSPEAPCNGMRNGGDEGSTPTLTVLPACRA 101

  Fly    48 QLVKIE-QLPDRGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFILPYIITLFLAGIPM 111
            ::..:: ::.:|.:||.|:||:|||:|.|:.|||||||||:||:||||||::||:|.....|||:
 Frog   102 EIQHLQTEIGERETWSKKIDFLLSVIGYAVDLGNVWRFPYVCYQNGGGAFLIPYVIMAVFGGIPL 166

  Fly   112 FFMELALGQMLTIGGLGVF-KIAPIFKGIGYAAAVMSCWMNVYYIVILAWAVFYFFMSMRADVPW 175
            |:||||:||....|.:.:: ||.|:|||||||..:::.::..||..|:|||::|...|.|:::||
 Frog   167 FYMELAMGQYHRNGCISIWRKICPLFKGIGYAICMIALYVAFYYNTIMAWALYYLIFSFRSELPW 231

  Fly   176 RTCNNWWNTVNCVSQYERKNLHCWDKIINGTTQKVCSVSALNITSLELTDPVKEFWERRALQI-- 238
            .:|.|.|||.||.:.::..::. |..         .|:|           |.:||:.|..|||
 Frog   232 TSCLNEWNTGNCTNYFQNSSVG-WSN---------SSIS-----------PAEEFYTRLVLQIHK 275

  Fly   239 SHGIEEIGNIRWELAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFPYVLLTILLVRGITLPGAL 303
            |.|:.::|.|.|:|...|||::.:.||.||||||.:||||:.||.|||::|.:||:||.|||||.
 Frog   276 SKGLHDLGGISWQLTLCLLLIFTVVYFSIWKGVKTSGKVVWVTATFPYIVLALLLIRGATLPGAW 340

  Fly   304 EGIKFYIIPNFSKLTNSEVWIDAVTQIFFSYGLGLGTLVALGSYNKFTNNVYKDALIVCTVNSST 368
            .|:.||:.|::.||..:.||:||..|||||.|.|.|.|:|..|||||.||.|:||||..|||..|
 Frog   341 RGVLFYLQPDWEKLLTTAVWVDAAAQIFFSLGPGFGVLLAFASYNKFHNNCYQDALITSTVNCMT 405

  Fly   369 SMFAGFVIFSVIGFMAHEQQRPVADVAA-SGPGLAFLVYPSAVLQLPGSPMWSCLFFFMLLLIGL 432
            |..:|.|||:|:|:||..:...|::||. :||.|.|:.|..|:..:|.|..::.:||.||:.:||
 Frog   406 SFMSGLVIFTVLGYMAEMRNLDVSEVAKDTGPSLLFITYAEAIANMPASTFFAIIFFLMLITLGL 470

  Fly   433 DSQFCTMEGFITAIIDEWPQLLRKRKEIFIAIVCALSYLVGLTCITQGGMYIFQILDSYAVSGFC 497
            ||.|..:||.|||::||:|.:..||:|:|:.::.::.:|..|:.:|.||.|:.::.:.|| :|..
 Frog   471 DSTFAGLEGVITAVLDEFPHIWGKRRELFVFLLISVCFLGALSTLTFGGAYMVKLFEEYA-TGPA 534

  Fly   498 LLWLIFFECVSISWCYGVDRFYDGIKDMIGYYPTVWWKFCWCVTTPAICLGVFFFNIVQWTPVKY 562
            :|.::|.|.:::||.||:::|...:::|:|:.|..:||.||....|...|.:....:.....::.
 Frog   535 VLTVVFLEAIAVSWFYGINQFCRDVREMLGFSPGWFWKICWVAICPLFLLFIICSFMSSPPDLRL 599

  Fly   563 LDYSYPWWAHAFGWFTALSSMLYIPLYMFWLWKRTPGELSEKIRALVRIDEDVTR 617
            .:|.||.|....|:....||.:.:|.||.:|...|||.:.|  |.|..|..:|:|
 Frog   600 FNYQYPSWTVVLGYCIGTSSFICVPAYMVYLLTSTPGSIKE--RFLKSITPEVSR 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	236/556 (42%)
slc6a4	XP_017946918.1	5HT_transport_N	48..91	CDD:367522	6/42 (14%)
		SLC5-6-like_sbd	113..649	CDD:382020	237/559 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010