Protein Alignment Gat and slc6a7

DIOPT Version :10

• Sequence 1: NP_651930.2
• Gene: Gat / 43805
• FlyBaseID: FBgn0039915
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_002940131.3
• Gene: slc6a7 / 100487063
• XenbaseID: XB-GENE-479449
• Length: 634
• Species: Xenopus tropicalis
• Alignment Length: 576
• Identity: 263/576 - (45%)
• Similarity: 362/576 - (62%)
• Gaps: 23/576 - (3%)

  Fly    37 SPTTTDTSNKQQLVKIEQLPDRGSWSSKMDFILSVVGLAIGLGNVWRFPYLCYKNGGGAFILPYI 101
            ||:..|.:.    :.||...|||:||.|:||:||.:|..:||||||||||..|.||||||::||.
 Frog    20 SPSDRDDTE----LDIEYPEDRGNWSGKLDFLLSCIGYCVGLGNVWRFPYRAYTNGGGAFLIPYF 80

  Fly   102 ITLFLAGIPMFFMELALGQMLTIGGLGVFKIAPIFKGIGYAAAVMSCWMNVYYIVILAWAVFYFF 166
            |.|.:.|||:|||||:|||..::|.|.|:||:|:|||:|....::...:.:||.:|:|:.:||.|
 Frog    81 IMLAICGIPLFFMELSLGQFSSLGPLAVWKISPLFKGVGMGMLLIVALVAIYYNMIIAYVLFYLF 145

  Fly   167 MSMRADVPWRTCNNWWNTVNCVSQYERKNLHCWDKIINGTTQKVCSVSALNITSLELTDPVKEFW 231
            .|:.:.:||..|.|||||..|:..:          :|.      .|.|||.:.......|.:|:|
 Frog   146 ASLTSSLPWEHCGNWWNTDLCLDHH----------VIR------ASNSALLVNISNTVSPSEEYW 194

  Fly   232 ERRALQI--SHGIEEIGNIRWELAGTLLLVWILCYFCIWKGVKWTGKVVYFTALFPYVLLTILLV 294
            .|..|.|  |.||.:.|.:||:|...|||.|.:.|.||.||||.:||||||||.|||::|.:||:
 Frog   195 SRYVLHIQGSSGIGDPGQLRWKLCLCLLLSWTIVYLCILKGVKSSGKVVYFTATFPYIILVMLLI 259

  Fly   295 RGITLPGALEGIKFYIIPNFSKLTNSEVWIDAVTQIFFSYGLGLGTLVALGSYNKFTNNVYKDAL 359
            ||:||.||..|||||:.|.|..|..|:|||:|..|||:|.|:|.|.|:...|||.|..|:|:|..
 Frog   260 RGVTLEGAWIGIKFYLTPQFEHLLTSKVWIEAALQIFYSLGVGFGGLLTFASYNTFHQNIYRDTF 324

  Fly   360 IVCTVNSSTSMFAGFVIFSVIGFMAHEQQRPVADVAASGPGLAFLVYPSAVLQLPGSPMWSCLFF 424
            ||...|:.||:.|||.||||:|:|:.|...||..||.:||||||:|||.|:..||.||.||.|||
 Frog   325 IVTLGNAFTSILAGFAIFSVLGYMSQELGVPVDQVAKAGPGLAFVVYPQAMTMLPLSPFWSFLFF 389

  Fly   425 FMLLLIGLDSQFCTMEGFITAIIDEWPQLLRKRKEIFIAIVCALSYLVGLTCITQGGMYIFQILD 489
            ||||.:||||||..||..:|||.||:|..||.:|.:|.||:|...:|:||...|.||||...:||
 Frog   390 FMLLTLGLDSQFAFMETIVTAITDEFPYYLRPKKAVFSAIICVALFLLGLILATDGGMYWLVLLD 454

  Fly   490 SYAVSGFCLLWLIFFECVSISWCYGVDRFYDGIKDMIGYYPTVWWKFCWCVTTPAICLGVFFFNI 554
            .|: :||.||.::...|:|:|..||:..|...|:.|:|:.|.:::|.||...:|...:.:..::|
 Frog   455 DYS-AGFGLLVIVITFCLSVSRVYGIKNFCRDIQMMLGFKPGLYFKACWIFLSPVTLMCLLAYSI 518

  Fly   555 VQWTPVKYLDYSYPWWAHAFGWFTALSSMLYIPLYMFWLWKRTPGELSEKIRALVR 610
            :::.|.:|..|.:|.|:.|.|....|.|.:.||:.|.....:..|.|.|:||...|
 Frog   519 LKYQPSQYGSYKFPLWSEALGILMGLLSCMMIPIGMLVAILKEEGSLWERIRQASR 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	257/555 (46%)
slc6a7	XP_002940131.3	SLC5-6-like_sbd	37..581	CDD:444915	257/555 (46%)