Protein Alignment Gat and slc6a14.2

DIOPT Version :9

• Sequence 1: NP_651930.2
• Gene: Gat / 43805
• FlyBaseID: FBgn0039915
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_002939711.4
• Gene: slc6a14.2 / 100485126
• XenbaseID: XB-GENE-855704
• Length: 642
• Species: Xenopus tropicalis
• Alignment Length: 608
• Identity: 251/608 - (41%)
• Similarity: 370/608 - (60%)
• Gaps: 71/608 - (11%)

  Fly    24 SKELGHTTSLQSSSPTTTDTSNKQQLVKIEQLPDRGSWSSKMDFILSVVGLAIGLGNVWRFPYLC 88
            ||:||  |.::|     || .||          :||:||||.:::||:||.|:|||||||||||.
 Frog    17 SKDLG--THVES-----TD-ENK----------ERGNWSSKSEYLLSMVGYAVGLGNVWRFPYLT 63

  Fly    89 YKNGGGAFILPYIITLFLAGIPMFFMELALGQMLTIGGLGVFKIAPIFKGIGYAAAVMSCWMNVY 153
            :::|||||::||.|.|.|||:|:||:|.:|||..::|.:.::|:.|||:|:|....::|..:.:|
 Frog    64 FQHGGGAFLIPYAIMLALAGLPLFFLECSLGQFSSLGPVAMWKVLPIFEGVGITMVLISTLVTIY 128

  Fly   154 YIVILAWAVFYFFMSMRADVPWRTCNNWWNTVNCVSQYERKNLHCWDKIINGTTQKVCSVS---- 214
            |.||:|::::|.|.|..:.:||..|..|                 .|:..:.|.:.:|:|:
 Frog   129 YNVIIAYSLYYLFASFTSILPWSECFEW-----------------ADEKCSKTPKGLCNVTIGEE 176

  Fly   215 ---ALNIT---------------SLELTDPVKEFWERRALQISHGIEEIGNIRWELAGTLLLVWI 261
               .:|:|               .||...|.|::|::.||:.|.|:.|.||:.|.||..|||.||
 Frog   177 DIGMVNLTWVKANNYTCIANSTLYLETELPSKQYWDKVALRRSGGLHETGNVVWYLALCLLLAWI 241

  Fly   262 LCYFCIWKGVKWTGKVVYFTALFPYVLLTILLVRGITLPGALEGIKFYI--IPNFSKLTNSEVWI 324
            :....::||:|.:||||||||:|||.:|.|||:||.||.||.:||.|||  ..:.|||:|::||.
 Frog   242 IIGAALFKGIKSSGKVVYFTAIFPYAVLLILLIRGATLEGAYDGISFYIGTQSDISKLSNADVWK 306

  Fly   325 DAVTQIFFSYGLGLGTLVALGSYNKFTNNVYKDALIVCTVNSSTSMFAGFVIFSVIGFMAHEQQR 389
            ||.||||||.....|.||||.|||||.||.|.||::||..|..||:||||.|||::|.||.:.::
 Frog   307 DAATQIFFSLSTAWGGLVALSSYNKFHNNCYADAIMVCITNCLTSVFAGFAIFSILGHMAFKAEK 371

  Fly   390 PVADVAASGPGLAFLVYPSAVLQLPGSPMWSCLFFFMLLLIGLDSQFCTMEGFITAIIDEWPQLL 454
            .|.||..||..|||:.||.|:.|||.:|:||.|||||||.:||||||.::|...|.|.|.:|:::
 Frog   372 EVKDVVDSGFALAFIAYPEALSQLPVAPLWSILFFFMLLTLGLDSQFASVETITTTIHDAYPKVM 436

  Fly   455 RKRKEIFIAIVCALSYLVGLTCITQGGMYIFQILDSYAVSGFCLLWLIFFECVSISWCYGVDRFY 519
            :|.:.|.....|.:.:|:|:.|:||.|:|...::| |..:|:.:|.....|.|.|.|.||.:||.
 Frog   437 KKMRGIITVGACIMFFLLGILCVTQSGIYWVDLID-YFCAGWGILIAAILELVGICWIYGGNRFI 500

  Fly   520 DGIKDMIG---YYPTVWWKFCWCVTTPAICLGVFFFNIVQWTPVKYLDYSYPWWAHAFGWFTALS 581
            :.|:.|||   :...:||:.||...||.:...:|.:::|.:...|:.:.:||.|..|.||...:.
 Frog   501 EDIEMMIGKKHWIFWLWWRLCWFFLTPLLLTVIFIWSLVTFDTPKHGNVAYPSWGVALGWCMIIF 565

  Fly   582 SMLYIPLYMF--------WLWKR 596
            .:::||:...        .||:|
 Frog   566 CIIWIPILAVVKIIKAKGTLWER 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	241/574 (42%)
slc6a14.2	XP_002939711.4	SLC5-6-like_sbd	33..612	CDD:382020	241/574 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920