Protein Alignment Gat and slc6a15

DIOPT Version :9

• Sequence 1: NP_651930.2
• Gene: Gat / 43805
• FlyBaseID: FBgn0039915
• Length: 636
• Species: Drosophila melanogaster
• Sequence 2: XP_002931668.1
• Gene: slc6a15 / 100380162
• XenbaseID: XB-GENE-975885
• Length: 730
• Species: Xenopus tropicalis
• Alignment Length: 701
• Identity: 222/701 - (31%)
• Similarity: 350/701 - (49%)
• Gaps: 129/701 - (18%)

  Fly    19 ESIE--MSKELGHTTSLQSSSPTTTDTSNKQQLVKIEQLPD----RGSWSSKMDFILSVVGLAIG 77
            ||::  :|.|.....|.:.|....:|..:|.:  .||:..|    |.:|:||:.:||:.||.::|
 Frog    18 ESVKDLLSNEDSGDESFKKSELVVSDDVDKDR--DIEEGSDIDDERPAWNSKLQYILAQVGFSVG 80

  Fly    78 LGNVWRFPYLCYKNGGGAFILPYIITLFLAGIPMFFMELALGQMLTIGGLGVFK-IAPIFKGIGY 141
            |||||||||||.||||||:::||:|.|.|.|||:||:||::||.:..|.:||:. |:|...|||:
 Frog    81 LGNVWRFPYLCQKNGGGAYLVPYLILLLLIGIPVFFLELSVGQRIRRGSIGVWNYISPKMGGIGF 145

  Fly   142 AAAVMSCWMNVYYIVILAWAVFYFFMSMRADVPWRTCNNWWNTVNCVSQYERKNLHCWDKIINGT 206
            |:.::..::.:||.||:.|::|||..|.:..:||..|....|..|...:.|
 Frog   146 ASCIVCLFVALYYNVIIGWSLFYFSQSFQHPLPWDQCPLVKNASNTFVEPE-------------- 196

  Fly   207 TQKVCSVSALNITSLELTDPVKEFWERRALQISHGIEEIGNIRWELAGTLLLVWILCYFCIWKGV 271
                |          |.:.....:|.|.||.||:.|.|.|.:.|::...||..|||....:.||:
 Frog   197 ----C----------EKSSATTYYWYREALNISNSITEGGGLNWKMTLCLLAAWILVCLAMIKGI 247

  Fly   272 KWTGKVVYFTALFPYVLLTILLVRGITLPGALEGIKFYIIPNFSKLTNSEVWIDAVTQIFFSYGL 336
            :.:|||:||::|||||:||..|||.:.|.|:::||:....|....:...:||.:|.||:||:.||
 Frog   248 QSSGKVMYFSSLFPYVVLTCFLVRALLLNGSVDGIRHMFTPKLEIMLEPKVWREAATQVFFALGL 312

  Fly   337 GLGTLVALGSYNKFTNNVYKDALIVCTVNSSTSMFAGFVIFSVIGFMA----------------- 384
            |.|.::|..||||..||.:.||::|..:|..||:.|..|:|:|:||.|
 Frog   313 GFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATLVVFAVLGFKANIMNENCISKNTVKIVK 377

  Fly   385 -------------HE----------------------------------QQRPVADVAASGPGLA 402
                         |.                                  |.....:.:..|.|||
 Frog   378 YLEAGNLSWSNVPHHVNFSSMSAQDYNLVYYIFQKIKEEEFDSLGLDSCQIEDELNKSVQGTGLA 442

  Fly   403 FLVYPSAVLQLPGSPMWSCLFFFMLLLIGLDSQFCTMEGFITAIIDEWPQLLRKRKEIFIAIVCA 467
            |:.:..|:...|.||.||.:||.||:.:||.|.|.|:||.||.|:|.:    :.|||......|.
 Frog   443 FIAFTEAMTHFPASPFWSVMFFLMLVNLGLGSMFGTIEGIITPIVDTF----KVRKEPLTVGCCL 503

  Fly   468 LSYLVGLTCITQGGMYIFQILDSYAVSGFCLLWLIFFECVSISWCYGVDRFYDGIKDMIGYYPTV 532
            |::.:||..:.:.|.|...:.|.|:.: ..||.::..|.|:|:|.||:|:|.|.:|||:|:.|..
 Frog   504 LAFCIGLLFVQRSGNYFVTMFDDYSAT-LPLLIVVILENVAIAWVYGIDKFMDDLKDMLGFTPYK 567

  Fly   533 WWKFCWCVTTPAICLGVFFFNIVQ--WTPVKYLDY----------SYPWWAHAFGWFTALSSMLY 585
            ::.:.|...:|.:...:...:|||  ::|..|..:          |||.|..|......:.::|.
 Frog   568 YYYYMWKYISPVLLTILLMASIVQMGFSPPGYYAWIAEKASEERISYPPWGLAVCISLIVFALLP 632

  Fly   586 IPLYMFW----LWKRTPGELS-------EKIRALVRIDEDVTRLREKMLRE 625
            :|:....    |...:.|.|:       :.|:....:::|.:.:.||:..|
 Frog   633 VPVVFIVRTCNLIDDSTGSLASVSYKRGKMIKETSNLEDDASLIHEKIQSE 683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gat	NP_651930.2	SLC6sbd-TauT-like	58..611	CDD:271387	207/640 (32%)
slc6a15	XP_002931668.1	SLC5-6-like_sbd	61..640	CDD:382020	203/611 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920